Volunteer for NIAID-funded clinical studies related to syphilis on ClinicalTrials.gov.
Syphilis is easy to cure in its early stages. Penicillin, an antibiotic, injected into the muscle, is the best treatment for syphilis. If you are allergic to penicillin, your healthcare provider may give you another antibiotic to take by mouth.
If you have neurosyphilis, you may need to get daily doses of penicillin intravenously (in the vein) and you may need to be treated in the hospital.
If you have late syphilis, damage done to your body organs cannot be reversed.
While you are being treated, you should abstain from sex until any sores are completely healed. You should also notify your sex partners so they can be tested for syphilis and treated if necessary.
For updated information on treatment for syphilis, read the Centers for Disease Control and Prevention Sexually Transmitted Diseases Treatment Guidelines.
Last Updated October 28, 2014