NIAID supports research on the diagnosis, prevention, and treatment of infections caused by microbes, including those that have the potential for use as biological weapons. The research program to address biodefense includes both short- and long-term studies targeted at designing, developing, evaluating, and approving specific tools (diagnostics, therapies, and vaccines) needed to defend against possible bioterrorist-caused disease outbreaks.
NIAID research goals to diagnose, prevent, and treat tularemia include
The image, taken with a fluorescent microscope, shows mouse macrophages (red) untreated and treated with CLDC+MPF 12 hours after infection with a virulent strain of Francisella tularensis. Intracellular F. tularensis bacteria are stained green. On the left, untreated mouse macrophages fail to control replication of F. tularensis. In contrast, cells activated with the CLDC+MPF therapeutic (on the right) have nearly eliminated all of the bacteria. Credit: NIAID
Image comes from a study published online May 27, 2010, in PLoS Pathogens, Ireland et al.
Last Updated March 06, 2009