This study is investigating why some people who are healthy and have normal immune function become infected with cryptococcosis. Cryptococcosis is a fungal infection that typically affects people with HIV, cancer, or other conditions that weaken the body’s immune system. The infection can progress to pneumonia and meningitis, which may cause serious symptoms of lung, brain, and spinal cord disease, such as headaches, fever, cough, shortness of breath, confusion, and weakness. People who recover from cryptococcal meningitis often need long-term treatment with medication to prevent the infection from coming back. This study may help NIH researchers in Bethesda, Maryland, learn why some previously healthy individuals get infected with Cryptococcus—information that may help develop better treatment and prevention strategies for patients in the future.
You may be eligible to participate if you
Study participants will receive free, expert medical care from an experienced team of healthcare professionals. Participants will visit the National Institutes of Health (NIH) Clinical Center for the initial appointment and then at least twice a year to monitor their health and to receive medical evaluations. Medical evaluations and procedures will vary based on a patient’s disease course and may include blood draws, lumbar puncture, and genetic testing.
The study is being conducted at the NIH Clinical Center in Bethesda, Maryland. The NIH campus is accessible by car and public transportation.
There is no charge to participate in this research study. All study-related medical care, including clinic visits, procedures and medications, are provided free of charge.
No, you will not be compensated for your participation in the study. Transportation and other expenses may be covered.
NIH Patient Recruitment and Public Liaison OfficeToll Free: 1-800-411-1222TTY: 1-866-411-1010Se habla español.Email: firstname.lastname@example.org
To learn more about this study of patients with cryptococcosis (trial ID: NCT00001352), visit ClinicalTrials.gov.
Last Updated December 20, 2011