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NIAID HIV and Emerging Infectious Diseases Program

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Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

(P-MOBILE – Protocol #14-I-0020)

The purpose of this study is to collect blood from people with "idiopathic CD4 lymphocytopenia", or ICL, and healthy volunteers. Specifically, we are interested in studying special blood cells called stem cells. Stem cells form the blood in our bodies by producing billions of new blood cells each day. Many of these blood cells help our bodies to fight infection including one group of immune cells called lymphocytes.

People with ICL have a low number of lymphocytes and are at risk of frequent infections that can be severe. We will use the blood collected in this study to conduct research in mice and in the laboratory that may provide new information about what causes ICL and what might be done to treat it.  Volunteers will be compensated.

Last Updated December 20, 2013