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Volunteer for Clinical Studies

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Volunteer for a Herpes Vaccine Research Study

The study is testing the safety of a vaccine for herpes simplex virus-2 (HSV-2). In the United States, HSV-2 affects approximately 16 percent of persons aged 14 to 49. HSV-2 genital infection increases the risk of getting HIV or giving it to someone else. This virus can cause severe disease in people with immature or compromised immune systems. No vaccine is currently available.

Who can participate?

You may be eligible if you are

  • 18 to 40 years old
  • Residing within 60 miles of National Institutes of Health (NIH) in Bethesda, Maryland
  • A healthy volunteer with or without cold sores and/or genital herpes
  • Willing to use birth control

What does the study involve?

Study participants will have two screening visits and then 10 or more visits over the course of a year. All volunteers will be compensated for their time.

Where is the study taking place?

The study is being conducted at the Warren Grant Magnuson Clinical Center (Building 10) at NIH. The NIH campus is accessible by car and public transportation.

How much does it cost?

There is no charge to participate in this research study. All study-related medical care and procedures are provided free of charge.

Will I receive payment?

Yes, you will be compensated for your participation in the study.

How do I find out more or volunteer?

If you are interested in volunteering for this study, go to the study’s confidential online questionnaire or contact

Office of Patient Recruitment, NIH Clinical Center
Toll free: 1-800-411-1222 (reference 13-I-0172)
TTY: 1-866-411-1010 Se habla español
Office hours: 8:00 a.m.-3:30 p.m. Eastern Time

To learn more about this study (trial ID: NCT01915212), visit and read some frequently asked questions.

Last Updated September 08, 2014

Last Reviewed February 13, 2015