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Why do certain people have recurrent or severe staph infections?
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About the Study

Staph infections are caused mostly by the bacteria Staphylococus aureus. Currently we do not understand why some individuals who are otherwise healthy become very sick with the infection in their blood, bones, lungs, or internal organs, while others have the same infection only in their skin or soft tissue and remain relatively healthy.

This study will help us learn more about how the immune system handles staph infections and hopefully lead to improved treatment and prevention of infections.

What does the study involve?

Participation in this study involves up to two visits. There is no charge for study-related tests.

Where is the study taking place?

The study is being conducted at the NIH Clinical Center (Building 10) on the NIH campus in Bethesda, Maryland. The NIH campus is accessible by car and public transportation.

Who can participate?

You may qualify if you:

  • Are 2 years of age or older (parents must give permission for minors to participate)
  • Have a current or past staph infection

You may not qualify if you:

  • Have contracted a healthcare-associated infection, for example from a surgery, dialysis, or a hospitalization
  • Are HIV-positive or have cancer, diabetes, or an an immune system deficiency.

To learn more about this study of invasive and recurrent Staphylococcus aureus Infection (Trial ID: NCT00911430), please visit

For questions about participating in this clinical study, contact:

Patient Recruitment and Public Liaison Office
Toll Free: 1-800-411-1222
TTY: 1-866-411-1010
Se habla español.

Read more about NIAID's role in addressing antimicrobial resistance.

Last Updated October 26, 2011

Last Reviewed February 09, 2011