Vaginal yeast infection, or vulvovaginal candidiasis, is a common cause of vaginal irritation. Approximately 75 percent of all women will get a yeast infection in their lifetime. This study is trying to determine why taking antibiotics sometimes increases a woman’s risk of getting a yeast infection.
You may be eligible if you are
Volunteers will visit the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland, for a screening visit. Eligible participants will have seven or more visits over three months and will keep a daily diary for the first month. Most participants will receive a ten-day course of a common antibiotic, amoxicillin. It is anticipated that some women will develop a vaginal yeast infection while others will not, allowing researchers to study how amoxicillin affects the microorganisms that normally live in the vagina, and how these changes are associated with getting a vaginal yeast infection.
The study is being conducted at the NIH Warren Grant Magnuson Clinical Center in Bethesda, Maryland. The NIH campus is accessible by car and public transportation.
There is no charge to participate in this research study. All study-related medical care and procedures are provided free of charge.
All study participants will receive financial compensation.
To see if you may qualify or for more information, contact
Office of Patient Recruitment, NIH Clinical CenterToll Free: 1-877-999-5557 (reference 13-I-0181)TTY: 1-866-411-1010 Se habla español.Email: VMB@niaid.nih.govOffice hours: 8:00 a.m.-3:30 p.m. Eastern Time
To learn more about this study of antibiotic-induced vaginal yeast infection (trial ID: NCT01915251), visit ClinicalTrials.gov.
Last Updated August 20, 2013
Last Reviewed February 13, 2015