Staff Scientist

Job Announcement Description

A staff scientist position is currently open in the Molecular and Cellular Immunoregulation Section (MCIS), Laboratory of Immune System Biology (LISB), Division of Intramural Research (DIR), National Institute of Allergy and Infectious Diseases (NIAID). MCIS aims to address heterogeneity and plasticity of CD4 T helper (Th) and innate lymphoid cell (ILC) subsets regulated by transcription factor complexes. The team utilizes multicolor “reporter,” conditional knockout, fate-mapping, and CRISPR/Cas9 murine models as well as RNA-seq, ChIP-seq, and single-cell technologies to study Th and ILC subsets in autoimmune, allergic, and infectious settings. Major areas of research at the MCIS include:

  • Diversity and plasticity of Th subsets
  • Development and functions of ILC subsets
  • Transcriptional regulation of lineage-specific genes

This position is for a staff scientist with an exceptional publication record and rich experience in immunology, cell biology, and molecular biology as well as related hands-on techniques including in vitro culture for Th cell differentiation and ILC development, in vivo animal studies (general immunization, infection with various pathogens, and induction of allergic or autoimmune diseases), and genome-wide analysis (such as RNA-seq, ChIP-seq, and DNase-seq). The incumbent in this position will be part of the team utilizing genetically modified mouse models developed (or being developed) in the LISB-MCIS to mainly investigate the differential regulation of the development of innate and adaptive lymphocytes focusing on the functions of key transcription factors (such as T-bet and GATA3) during Th cell differentiation and ILC development. The incumbent will be expected to carry out his/her own projects, to help/supervise other research personnel including postdoctoral fellows, to train new lab members as well as to provide scientific and administrative support to the whole lab, including active involvement in group discussions on the lab projects, technical support to other lab members, routine maintenance of lab equipment, and ordering laboratory supplies and reagents when needed. The incumbent will report directly to Dr. Jinfang Zhu, Section Chief, MCIS, LISB, NIAID, who will determine the priorities of research projects within MCIS and the research responsibilities of the incumbent. The initial appointment is for 3-5 years, and the position may be renewed every 5 years thereafter depending on the performance of the incumbent.

See more about MCIS, LISB, and DIR.


  • Interested candidates must possess a doctoral degree (M.D. or Ph.D.).
  • U.S. citizenship is not required.

To Apply

Interested candidates should send their curriculum vitae (CV), bibliography, and a one-page statement on their background and interests in the position to

HHS, NIH, and NIAID are equal opportunity employers dedicated to diversity, equity, inclusion, and accessibility.

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