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See the list of featured NIAID clinical trials below or view the complete list of NIAID studies recruiting participants on ClinicalTrials.gov.
Currently, people with immune disorders fall outside of guidance for COVID-19 vaccination, as they are typically excluded from vaccine trials.
The goal of this study is to evaluate the safety and efficacy of BIO 300 Oral Suspension to improve lung function in patients that were previously hospitalized with COVID-19 related pulmonary complications.
The main purpose of NIAID's TICO is to learn if new treatments are safe and can help people in the hospital with COVID-19 get better and go home faster.
The primary purpose of NIAID's ACTIV-5/BET study is to evaluate the efficacy of investigational therapeutics in adults hospitalized for COVID-19.
This is a national study that will compare the immune response to additional COVID‐19 vaccine doses in participants with autoimmune disease who did not mount an adequate response to the initial vaccination regimen.
A study to learn how coronavirus affects different organs of the body and the function of the body's immune system.
The NIAID Vaccine Research Center is looking for volunteers who are recovered from COVID-19 infection to donate blood for a research study.
The primary objectives of this study are to evaluate the safety and reactogenicity of delayed heterologous or homologous vaccine doses after Emergency Use Authorization (EUA)-dosed vaccines and to evaluate the breadth of the humoral immune responses of heterologous and homologous delayed boost re
This study looks at the safety and effectiveness of different drugs in treating COVID-19 in outpatients. Participants in the study will receive an experimental therapy or a placebo.
This NIAID research study focuses on an experimental drug which may help treat COVID-19 by supporting the immune system.
The goal of this study is to learn more about the genetic contributions to the severity of disease in COVID-19. We hope to use this information to develop therapies to reduce the severity of symptoms of COVID-19 in some people.
The primary objectives of this study are to evaluate the short- and long-term health outcomes of SARS-CoV-2 infection in children, including multisystem inflammatory syndrome in children (MIS-C), and to characterize the immunologic pathways associated with different disease presentations and outcomes.
A study about how SARS-CoV-2, the virus that causes COVID-19, affects the body, specifically how it affects blood cells and the immune system.
A study about long-term medical problems experienced by people who recover from COVID-19 and whether people who recover develop long-term immunity to SARS-CoV-2, the virus that causes COVID-19.
The COVID-19 Prevention Network (CoVPN) is conducting studies to find safe and effective vaccines and monoclonal antibodies for (SARS-CoV-2), the virus that causes COVID-19.
Are you an NIH staff member? If you have some time and have an interest in helping researchers make discoveries about COVID-19 and influenza, we need you!
We are interested in learning about long-term immunity in people who receive COVID-19 and/or flu vaccines.
This study evaluates the response of the immune system, the part of the body that helps fight infections, to the seasonal influenza vaccine in healthy individuals and also investigates whether prior SARS-CoV-2 infection may change that response.
Now that COVID vaccines have been approved for children this research is being expanded to determine whether highly allergic children or children with mast cell disorders (a buildup of the white blood cells that release substances causing symptoms similar to an allergic reaction) are more likely