Diseases & Conditions
Grants & Contracts
News & Events
See the list of featured NIAID clinical trials below or view the complete list of NIAID studies recruiting participants on ClinicalTrials.gov.
We are studying a condition called paradoxical reaction that some people get when they take treatment for tuberculosis (TB). Most people with TB feel better after starting treatment. But for some people, the opposite happens. They may feel better at first, but then suddenly get worse. This opposite effect is a paradoxical reaction. We do not understand how this reaction happens. It can be hard to tell whether worsening symptoms are caused by a paradoxical reaction or something else, such as if the treatment just is not working.