Find a Clinical Trial

See the list of featured NIAID clinical trials below or view the complete list of NIAID studies recruiting participants on ClinicalTrials.gov.

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Allergic Diseases and Eczema (Atopic Dermatitis)

Online Survey About Eczema

This 10- to 20-minute survey is available for patients with eczema or parents of patients with eczema.  These questions will help us learn more about patient experiences to improve current research and guide future research. 

Arthritis

Rheumatoid Arthritis Studies

NIAID is committed to advancing the understanding of how and why autoimmune diseases such as rheumatoid arthritis occur.

Asthma

Preventing Asthma in High Risk Kids (PARK)

This trial is a randomized, double-blind, placebo controlled trial designed to test whether two years treatment of preschool children aged 2-3 years of age at high risk for asthma with omalizumab (anti-IgE) for two years will prevent the progression to childhood asthma, as reflected by a reduction in the prevalence of active asthma in the Final 12 months during 2 year observation period off study drug.

Chronic Granulomatous Disease (CGD)

Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995

This study will determine the long term medical condition and daily functioning of participants with CGD after a transplant and if possible, compare these results to participants who do not undergo a transplant.

Coronaviruses

Big Effect Trial (BET) for Finding Promising Treatments of COVID-19

The primary purpose of NIAID's ACTIV-5/BET study is to evaluate the efficacy of  investigational therapeutics in adults hospitalized for COVID-19.

Diabetes

TrialNet Pathway to Prevention of Type 1 Diabetes

The goal of this study is to enhance understanding of the demographic, immunologic, and metabolic characteristics of individuals at risk for developing type 1 diabetes.

Type 1 Diabetes Extension Study (T1DES)

The goal of this study is to further the understanding of the immunologic mechanisms underlying maintenance and loss of beta cell function by evaluating the relationship between longitudinal changes in beta cell function and changes over time in biomarkers known to be associated with a response to immune modulating treatments used in prior clinical trials.

Flu (Influenza)

Analysis of Bone Marrow and Blood B Cell Immune Responses to Influenza Vaccination

The study is designed to assess the humoral response to influenza vaccination and the longevity of humoral immunity to influenza vaccination in healthy adults.

Evaluation of Human Immune Responses to Influenza Virus Vaccination in Healthy Volunteers

This is an open label single arm observational study of longitudinal immunologic responses to influenza vaccine in healthy adults.

Hepatitis

Monitoring SOF/VEL in Treatment Naïve, HCV Participants With Active Infection (MINMON)

This study is trying to see whether taking an HCV treatment with fewer clinic visits and laboratory tests can cure just as many people as the standard approach that uses more visits and laboratory tests.

HIV/AIDS

Help End HIV - Red Ribbon Registry

HIV remains a major health issue globally and within the United States. Recent audience research found that many Americans are not aware that HIV is still a health issue in the U.S., are unsure if they might be vulnerable to exposure, and do not know if there is a cure.

Safety and Efficacy Study of Injectable Cabotegravir Compared to Daily Oral Tenofovir Disoproxil Fumarate/Emtricitabine (TDF/FTC), For Pre-Exposure Prophylaxis in HIV-Uninfected Cisgender Men and Transgender Women Who Have Sex With Men

This study will evaluate the safety and efficacy of the injectable drug cabotegravir (CAB LA), for pre-exposure prophylaxis (PrEP) in HIV-uninfected cisgender men and transgender women who have sex with men (MSM and TGW).

Lupus

Clinical Research Studies of Systemic Lupus Erythematosus

Lupus is an autoimmune disease characterized by inflammation of different tissues of the body. The most common type of lupus is systemic lupus erythematosus (SLE). Women are at far greater risk than men of developing lupus, and SLE disproportionately affects minority populations.

Lyme Disease (Borreliosis)

Human Immune Response to Ixodes Scapularis Tick Bites

The aim of this study is to learn how peoples’ bodies, particularly the skin, respond to tick bites.