NIAID Funding News

NIAID Funding News

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NIAID Funding News provides funding, policy, and other information to NIAID's extramural research community and Institute staff. You can subscribe directly by entering your email address at Email Updates and then selecting your subscription topics. Visit Stay Informed About Policy Changes and News for more opportunities to connect with us.

Quiz Yourself on NIH Grant Funding Terminology

How familiar are you with NIAID’s application and grant terminology? Test your knowledge by taking our quiz and pay attention to the explanations for each answer.
A HISTEP student checks the eye color or her fruit flies during a genetics experiment.

There’s More to Biosafety and Biosecurity Than Select Agents

Review key terminology like dual use research of concern, enhanced potential pandemic pathogens, select agents, and recombinant or synthetic nucleic acid molecules.
Colorized scanning electron micrograph of Ebola virus particles both budding and attached to the surface of an infected VERO E6 cell

Address Just-in-Time Requests and Bars to Award Quickly

While most of the just-in-time information we request is routine, be aware that certain codes and comments in your summary statement can indicate a funding restriction or bar to award.
A photo of a woman and man sitting at a desk filling out paperwork.

Highlight Preliminary Data in Your Next Application

Focus on what reviewers would like to see in your application: enough information to convince them that your proposed project can be accomplished and is likely to have a high impact.
Researcher checks western/moisture blots to know if proteins bind to antibodies.

Generate Your Own Lists of Recently Funded Grants

You can create a list of recently funded NIAID grant awards to better assess the direction of preferences and priorities for NIAID peer reviewers and program staff.
Colorized scanning electron micrograph of Group A Streptococcus (Streptococcus pyogenes) bacteria and a human neutrophil.

Stay on Top of SAM Renewals and Organizational Registrations

NIAID cannot provide grant funds to organizations with an expired System for Award Management (SAM) registration; this includes competing and noncompeting awards.
3D print of hemagglutinin (HA), one of the proteins found on the surface of influenza virus that enables the virus to infect human cells

Reviewing NIAID’s Application and Award Counts for FY 2022

We share the number of R01-equivalent and R21 applications that NIAID received in the previous fiscal year (FY) as well as how many awards NIAID made in turn.
Respiratory syncytial virus (RSV) in cross-section landing on the surface of a human respiratory endothelial cell. Single stranded RNA (colorized purple) is shown wrapped around a nuclear protein core capped by large L proteins.

Appreciation for 2022 NIAID Peer Review and Committee Volunteers

On behalf of NIAID and our research community, we express our deepest gratitude to fiscal year 2022 review and advisory group volunteers for donating their precious time and effort.
VRC scientists working with a Biomek Nxp robot, which is used to set up and harvest cultures of HIV patients' B cells that are used in the discovery of novel HIV neutralizing antibodies.

Top Ten Things NIH RePORT and RePORTER Can Do for You

Use custom crafted queries to learn what active research projects represent the cutting edge of your field, find potential collaborators for future projects, and much more.
Bar graph shows number of active projects at each NIH institute and center.

Know the Basics for Facilities and Administrative Costs

Facilities and administrative costs pay for common or joint objectives that cannot be readily identified with an individual project or program. Examples include payroll, departmental administration, student services, building depreciation, and utilities.
Workbench in NIAID intramural laboratory, with supplies and equipment.

November ACD Meeting Featured a Trio of Proposals

The NIH Advisory Committee to the Director (ACD) discussed a new framework for peer review criteria, NIH-supported postdoctoral training, and alternative methods to advance biomedical research.
Noni Byrnes, Ph.D., Director, Center for Scientific Review

Remember to Register, Review, and Update Records at ClinicalTrials.gov

Those conducting an NIH-funded clinical trial must promptly update study records, including updates in the recruitment status or study completion date(s), made no later than within 30 days of the occurrence.
Radiology Imaging at the NIH Clinical Center

Small Businesses—Set Your Sights on Phase III

Though NIAID does not fund small businesses directly for commercialization, our aim is to set up small businesses for later success during the earlier phases of the Small Business Innovation Research and Small Business Technology Transfer programs.
prototype of a smart bandage equipped with temperature and pH sensors

Applicants—Understand What a Cooperative Agreement FOA Signifies

A cooperative agreement is a support mechanism that NIH frequently uses for high-priority research areas that require a level of involvement from NIH staff that is higher than for a typical research project grant.
Volunteer in trial of candidate universal flu vaccine receives injection

A Summary of September’s Advisory Council Meeting

NIAID Director Dr. Anthony Fauci said, "It has been an enormous pleasure and privilege of my job to have worked with the many extraordinarily intelligent and talented individuals who have served Council over the years.” 
NIAID Director Dr. Anthony Fauci

Help Spread the Word of a New NIH Fellowship Program

The NIH Medical Scientist Partnership Program will be a trans-NIH effort to support combined degree candidates by providing them an option to conduct doctoral research in an NIH Intramural laboratory.
Participants in the NIH Medical Research Scholars Program

Understand the Fiscal Year Calendar to Sync Your Timing

Recognizing how NIH deadlines correspond to the fiscal year calendar can help you understand when and why NIAID undertakes certain actions and processes.
Colorized transmission electron micrograph of a single Nipah virus particle

NIAID Prioritizes a Robust Population of Physician-Scientists

By virtue of their training, experiences, and responsibilities as clinicians, physician-scientists are uniquely positioned to identify research priorities and pursue breakthroughs inspired by patient care.
Treating an Eczema Patient

Brush Up on the Basics of a Modular Budget

The modular budget form includes prompts to attach a Personnel Justification, Consortium Justification, and Additional Narrative Justification, which collectively justify your budget to peer reviewers.
Treatments for the common cold stock photo

Know Your Closeout Obligations at Project’s End

Failure to submit reports when they are due may result in NIH's taking enforcement actions against your institution for not complying with grant closeout procedures. Follow our advice to complete this process on time and without issue.
Universal Flu Vaccine Trial Volunteer Receives Injection

Recapping June’s Advisory Council Meeting

At the 201st meeting of NIAID’s Advisory Council, NIAID Director Dr. Anthony Fauci gave remarks on NIAID’s budget, outreach activities, scientific priorities, and research outcomes.
Colorized scanning electron micrograph of mpox virus on the surface of infected VERO E6 cells

R21 Grants Make for Slippery Stepping Stones

The exploratory/developmental grant (R21) activity code provides up to two years of funding support. Typically, direct costs for the entire project period are capped at $275,000.
materials on a lab bench

Reference NIH’s Biomedical Research and Development Price Index

In general terms, the Biomedical Research and Development Price Index indicates how much money is needed to purchase the same amount of biomedical research as the year before.
NIH Director Francis S. Collins and NCATS Director Christopher P. Austin talk with U.S. Senator Barbara A. Mikulski

Respond to Just-in-Time Requests and Any Bars to Award

Most just-in-time information requested by NIAID staff is routine, but certain codes in your summary statement can indicate an award restriction or bar to award.
Clinical trial volunteer receives wristband

A Deep Dive Into Data Management and Sharing

NIH's new policy requires both effective data management with the development of data management and sharing plans as well as maximum data sharing in a timely manner.
Work station in a research laboratory

Find a Fiscal Year 2021 Research Overview, Related Databases

If you are keen on data, you’ll likely want to read on for funding and success rate data on fiscal year 2021 NIH and NIAID awards, as well as databases you can use to find more information.
DNA sample is isolated and ready for storage

NIH and Tribal Nations—Commitment and Collaboration

Regular, meaningful engagement with Tribal partners helps NIH ensure American Indians and Alaska Natives are well-represented in research and benefit from its outcomes.
NIAID Director Dr. Anthony Fauci and THRO Director Dr. David Wilson

Director of NIAID’s Vaccine Research Center Announces Retirement

Dr. John Mascola provided leadership for scientific and clinical research activities and developed vaccine research programs for priority diseases, including HIV, influenza, Ebola/Marburg, malaria, and COVID-19.
John Mascola Shaking Hands with Barack Obama

Thank You to 2021 NIAID Peer Review and Committee Volunteers

Our thanks to all who volunteer to serve on a peer review group or advisory committee; your time, effort, and contributions are critically important to help NIAID fund the best science.
Panel of Peer Reviewers

A Synopsis of January’s Advisory Council Meeting

Catch up on remarks from NIAID Director Dr. Anthony Fauci and a presentation from guest speaker Dr. Lyric Jorgenson, the acting NIH associate director for science policy and acting director of NIH’s Office of Science Policy.
Dr. Lyric Jorgenson

Know the Rules—NIH Peer Review Security and Confidentiality

Security and confidentiality in peer review are essential to safeguard the exchange of scientific opinions, protect confidential information, provide reliable input to NIH about research projects to support, and more.
CD8 T Cells Close to Wound After Staphylococcus Epidermidis Application

Know Where To Go for Insights Into Site Visits

Staff may conduct “not-for-cause” site visits, such as those for new foreign awardees, as well as “for cause” visits when NIAID has evidence of administrative or accounting deficiencies at an institution.
Researcher opens freezer door

NIAID Sometimes Funds Applications as the Secondary Institute

When an application spans multiple institutes' research priorities, NIH's Center for Scientific Review designates one institute as primary and the other(s) as secondary.
NIAID researcher reaching for cell cultures in a CO2 incubator

Don’t Be Fazed by Phased Awards

NIAID uses phased awards to provide support for high-risk projects and a rapid pathway to additional funding for those projects able to meet the high-risk goals within established timelines.
Researcher checks western/moisture blots to know if proteins bind to antibodies

Create a Strong Multiple PI Leadership Plan

Your team agreed to work together because you assume it will go well, so it’s easy to overlook or minimize how you will handle disputes. Be sure to plan a thorough process for resolving conflicts and disputes.
NIAID researcher uses an electron microscope.

For Foreign Investigators and Institutions—Know Eligibility Requirements

Applications from foreign institutions are strengthened when they include either expertise, study opportunities, or resources that are not easily available in the United States—for example, access to a unique study population or scientists with unusual skills or achievements.
Mosquito dissection under microscope

For Grant Applicants—A Focus on Facilities and Equipment

When building your application, work with your department chair or colleagues to identify the resources and level of support your institution can provide and external resources you can leverage.
Workbench in NIAID intramural laboratory, with supplies and equipment

A Summary of September’s Advisory Council Meeting

Catch up on remarks from NIAID Director Dr. Anthony Fauci and a presentation from guest speaker Dr. Steven Holland, director of the NIAID Division of Intramural Research.
Steven M. Holland, M.D.

RCDC Shares Spending Estimates and Disease Burden by Category

To match projects with relevant categories, NIH's Research, Condition, and Disease Categories (RCDC) uses sophisticated text data mining (categorizing and clustering using words and multiword phrases) and NIH-wide definitions.
Colorized scanning electron micrograph of a cell infected with a variant strain of SARS-CoV-2 virus particles (UK B.1.1.7), isolated from a patient sample.

Know How To Demonstrate Scientific Progress in Annual Reports

You need to describe scientific progress in your annual Research Performance Progress Report to demonstrate success and merit, even if the project is still ramping up.
Medical Examination of a Clinical Trial Volunteer

Recognize What You Need To Change Scope

You must obtain NIAID’s written prior approval before changing the scope of your research activities. Start by discussing with your program officer your situation and the changes you are considering.
Transmission electron micrograph of a SARS-CoV-2 virus particle

Know the Basics of Review Criteria

Scored review criteria receive separate scores, and both scored review criteria and additional review criteria contribute to the overall impact score. Additional review considerations do not affect the overall impact score.
a bowl of peanuts

Learn Procedures for Extramural and Intramural Researchers To Collaborate

Because intramural researchers are government employees, additional rules and regulations apply to their involvement on research projects supported by NIH extramural grant funding.
NIAID Liaison Greets Study Volunteer

Get To Know NIAID Small Business Programs

Our small business grant and contract funding opportunities help bridge the gap between basic science and commercialization of new therapies, vaccines, diagnostic tests, and other technologies.
Centrifugal Filter Units

How To Find the Right Mentor for Early-Career Awards

A mentor makes a long-term commitment to your career as an adviser, advocate, critic, and instructor whose guidance helps your scientific plans, professional development, and advancement.
Training on diagnostic procedures

A Refresher on Application Resubmission Strategy

Should your resubmission (A1) application go unfunded, you can submit a new application (A0), which does not need to be significantly different from the A1 so long as you remove any references to previous reviews from the A0.
Researchers train to use new equipment

Extramural Research Overview for Fiscal Year 2020

NIH’s fiscal year 2020 appropriation totaled $41.6 billion. Of that total, NIH spent $30.8 billion to award 56,169 new and renewed extramural grants to 2,650 U.S. and international organizations.
Dr. Francis Collins, NIH Director

Quiz Yourself on NIH Acquisitions Terminology

How familiar are you with NIAID’s solicitation and contract vocabulary? Test your knowledge by taking our quiz, and pay attention to the explanations for each answer.
Scientist using a calculator

Patents Part Two—A Closer Look at Reporting

Submitting a required invention disclosure to NIH through iEdison is not considered a “public disclosure” and will not jeopardize your patent rights. In fact, if you don’t submit a required invention disclosure to NIH, your patent rights will be in jeopardy.
Bayh and Dole

Know How To Answer Just-in-Time Requests, Resolve a Bar to Award

Certain codes in your summary statement can indicate an award restriction or bar to award, which can block you from funding until you resolve underlying scientific review concerns about human subjects involvement, inclusion, or animal welfare.
patient with tick bite

Insights Into Inventions—Reporting, Bayh-Dole, and More

Learn what actions you should take upon developing a unique or novel device, method, or process during the course of NIH-funded research.
Light bulb Edison

Highlights From January 2021 NIAID Advisory Council Meeting

In his remarks to NIAID’s Advisory Council, NIAID Director Dr. Anthony Fauci shared key staff transitions, legislative updates, and COVID-19 news.
Dr. Fauci at Vaccine Kick-Off Event

Writing a Winning Application—Write To Excite

Create a winning application by keeping your NIH peer reviewers in mind as you anticipate questions about your project's significance and innovation.
dissecting microscope

NIH or NIAID? Know the Difference

Familiarize yourself with the differences between NIH and its institutes and centers as related to funding and peer review.
IC Directors Collage

Writing a Winning Application—Consider the Review Committee

Match your research project to a review group with appropriate expertise and create an application that appeals to the reviewers and catches their interest by proposing concepts and preliminary data they would regard as innovative.
researcher uses a dissecting microscope

Opportunities and Resources

Initiative Takes International Approach to Infectious Diseases

Apply if you are an international investigator in a resource-constrained country and can propose high-priority, regionally relevant infectious diseases research.

Propose Research on Mechanisms of Viral Invasion of Central Nervous System

Apply if you can conduct research focused on less-studied emerging and re-emerging neurotropic viruses for which there are currently no approved vaccines or therapeutics.

Funding to Characterize Post-Tuberculosis Lung Disease in HIV-Infected Individuals

Conduct epidemiological and observational research projects on the long-term cardiopulmonary sequelae following treatment for tuberculosis in persons living with and without HIV infection.

ReVAMPP Network—NIAID Plans $100 Million for Pandemic Preparedness

A set of new initiatives will create research centers in support of the Research and Development of Vaccines and Monoclonal Antibodies for Pandemic Preparedness (ReVAMPP) Network.

New Program Will Boost Aspiring Clinician Scientists

Through its new Medical Scientist Partnership Program, NIH will sponsor predoctoral students pursuing both a clinical doctoral degree and a biomedical research doctoral degree.

Develop Vaccine Candidates for Sexually Transmitted Infections (STIs)

This initiative will focus on advanced vaccine development for STI pathogens that have limited candidates in the product development pipeline: Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum.

New Initiative Focuses on Food Allergy Research

NIAID established the clinical trial network Consortium for Food Allergy Research to address concerns about the increasing incidence of food allergy and paucity of treatment options.

Four Research Areas Comprise NIAID’s 2023 Omnibus Contract Solicitation

Successful offerors will help advance the research and development of promising candidate vaccines, therapeutics, and diagnostics for biodefense, emerging infectious diseases, and pandemic preparedness.

Contract Opportunity Renews NIAID Adjuvant Discovery Program

NIAID seeks to renew the Adjuvant Discovery Program, which supports the identification and characterization of novel, effective, and safe vaccine adjuvants.

Find Funding for Genetic Research on Ricksettial Pathogens

The initiative supports a two-phased approach that enables a dedicated period of tool development followed by the use of those tools to address gaps in our knowledge of select rickettsial diseases.

NIAID Releases RFA for International Centers of Excellence for Malaria Research

Help us improve understanding of malaria pathogenesis, epidemiology, and transmission, as well as evaluate, optimize, and inform development of interventions to understand, control, eliminate, and eventually eradicate malaria.

Apply to Integrated Preclinical/Clinical AIDS Vaccine Development Program

NIAID's initiative will fund a multidisciplinary consortium with expertise in vaccinology, animal models, molecular biology, cell biology, immunology, manufacturing, and adjuvant biology.

New Funding Opportunity Focuses on Immunity in Older Adults

Apply if you can develop mechanistic insights into innate and adaptive immune function changes that occur during the aging process in humans.

Take Note of a New TB-Related Notice of Special Interest

Find effective methods to measure rates of tuberculosis transmission that rely on understanding the biomedical basis of transmission and related risk factors, then develop and assess potential interventions.

Novel R01 Seeks New and “At-Risk” Investigators from Diverse Backgrounds

Through this new initiative, eligible individuals are invited to submit investigator-initiated research project grant applications within the scope of NIAID's scientific areas of focus.

Conduct Research to Improve Protective Immunity Following Immunization

NIAID will support studies that define and characterize components and mechanisms of the immune system that lead to sustained immunity and identify common versus distinct durable immune mechanisms triggered by vaccines compared to natural infection.

Review NIAID Topics for Small Business Innovation Research Contract Solicitation

The solicitation serves as a vehicle for small business offerors to propose research projects on a multitude of scientific topics from across NIH. Contract proposals are due November 4, 2022.

Identify Host Cell Death Pathway Targets for Tuberculosis Treatment

NIAID invites cross-disciplinary applications that focus on mechanistic studies of host cell death mechanisms involving host-tuberculosis interaction, innate and adaptive immunity, and target identification for interventions.

Another Opportunity for NIAID New Innovators Award Approaches

Our aim is to facilitate the movement of exceptional postdoctoral fellows into independent positions within an accelerated timeframe, and further support them as talented, newly independent faculty.

NIH Small Business Opportunities and Priority Topics for 2022

NIH recently issued 2022 parent funding opportunity announcements for Small Business Innovation Research and Small Business Technology Transfer grants.

Accelerate Diagnostic and Vaccine Development of Bacterial Sexually Transmitted Infections

Clinical history studies consider the full spectrum of infection and are composed of natural history—infection to screening and the interval after screening from treatment through follow-up exams.

Partnerships To Develop Vaccines Against Select Enteric Pathogens

NIAID will support milestone-driven preclinical research that will advance candidate vaccine development and production for select enteric pathogens or multivalent forms.  

New Contract Solicitation for Services To Support Developers of Candidate Diagnostics

Work with NIAID to provide product developers a discrete subset of services that will propel new in vitro diagnostic products toward regulatory clearance.

Undertake Limited Interaction Targeted Epidemiology for Viral Suppression

Propose to establish a large digitally-maintained cohort of 1,000 participants or more to prospectively investigate trajectories of HIV care engagement and viral suppression.

Develop Immunological Assays for Influenza Clinical Studies and Trials

Apply if you can build a well-integrated, cross-disciplinary research team with diverse expertise in assay development and optimization, clinical research, immunology, and influenza virology.

Research Early-Stage HIV Broadly Neutralizing Antibody Susceptibility Assays

NIAID encourages studies that facilitate early-stage assay development and demonstrate feasibility and clinical utility, followed by verification and late-stage method validation.

Participate in Immune Drivers of Autoimmune Disease Cooperative Research Program

Conduct research on the immunologic processes and events that drive not only the course of autoimmune disease but also the preclinical phase and the transition from subclinical autoimmunity to diagnosed autoimmune disease.

Predict Risk of TB Disease Progression in Children by Studying Biomarker Signatures

Biomarker signatures predictive of tuberculosis (TB) disease progression in children, if identified, could translate to simple, easy to use, point-of-care-based tools and allow targeted TB preventive chemoprophylaxis.

2022 NIAID Omnibus Contract Solicitation—Four Research Areas

Contract funds will support vaccine and therapeutic development through candidate testing; product manufacture; preclinical or nonclinical toxicology testing; and early clinical studies.

Apply for Research Funds To Address CDI Immunity and Vaccine Development

Pursue vaccine development by studying host immune responses to Clostridioides difficile infection (CDI) and leveraging clinical samples, identifying new protective antigens, and employing novel vaccine and adjuvant platforms.

Advance Universal Flu Vaccine Research Through New Initiative

Foster new and innovative scientific studies to produce vaccines with broader, more durable protection to limit the public health consequences of both seasonal and pandemic influenza.

Advance the Molecular and Genetic Characterization of Inborn Errors of Immunity

Help advance the experimental validation and functional characterization of genetic variants in genomic regions that result in inborn errors of immunity/primary immunodeficiency diseases.

Take Note of Reissued NOSI on Somatic Cell Gene Editing

NIAID will support research to apply somatic cell gene editing approaches to improve graft survival and outcomes for recipients of allogenic solid organ, pancreatic islet, or vascularized composite allograft transplants.

Explore Avenues to Broad Protection Against Group A Streptococcus Infections

To address unmet research gaps and obstacles, NIAID will fund research projects to promote and expand basic and translational research to advance promising Group A Streptococcus vaccine candidate discovery and evaluation.

Develop Microbiome-Related Approaches To Advance Understanding of Radiation Injuries

Explore how the presence of resident microbiomes in the body might affect the severity of radiation injuries sustained during a radiation or nuclear incident and how the microbiome itself is impacted by radiation exposure.

Small Businesses—New FOA Seeks Multipurpose Prevention Technologies

Develop multipurpose prevention technologies that prevent HIV infection and pregnancy in adolescent and young women while also taking a special interest in health disparity populations that are disproportionately infected.

Funding for Somatic Gene Cell Editing in Transplantation Research

Use somatic cell gene editing approaches to improve graft survival and outcomes for recipients of allogenic solid organ, pancreatic islet, or vascularized composite allograft transplants.

NOSI Focuses on Impacts of Arthropod Feeding on Host Immune Response

Conduct research to understand the role of arthropod salivary factors during and following blood feeding in establishing vector-borne pathogen infections, as well as facilitating immune-mediated diseases and immune modulation in the vertebrate host.

SBIR Contract Solicitation (PHS 2022-1) for Small Businesses

Small businesses are invited to submit research proposals in response to A Solicitation of NIH and CDC for Small Business Innovation Research (SBIR) Contract Proposals. The submission deadline is October 28, 2021, at 5 p.m. Eastern Time.

Explore Topics for 2021 Small Business Omnibus Grants

If you’re an entrepreneur or partner with a small business, don’t miss NIH’s reissued 2021 parent funding opportunity announcements for Small Business Innovation Research and Small Business Technology Transfer grants.

Epidemiology Research To Evaluate Impact of COVID-19 on the HIV Epidemic

NIAID is interested in research on strategies needed to adapt the HIV/AIDS response through agile and innovative support of prevention, care, and maintenance of sustained HIV viral suppression during the COVID-19 pandemic.

Vaccine Adjuvant Funding Opportunities and a Key Resource

NIAID has an ongoing and significant interest in supporting new vaccine adjuvants. Learn about the latest funding opportunities and a resource for querying adjuvant information.

For Faculty—A Chance To Enhance Research in Your “AREA”

The Academic Research Enhancement Award (AREA) provides funding for small-scale research projects that give undergraduate students an opportunity to gain significant biomedical research experience.

Propose a Consortium for HIV/AIDS Vaccine and Cure Research

NIAID will support a research program built around two integrated areas of scientific focus: identifying the correlates and mechanisms of protection of preventive vaccines and using vaccines or other immune modalities in advancing cure research.

New FOA “Centers” on HIV Structural Biology

The opportunity seeks dynamic, multidisciplinary consortia of structural biologists, virologists, and computational scientists to resolve complex biological structures relevant to HIV prevention, treatment, and cure.

Control Viral Infection Through an Understanding of HIV Reservoir Dynamics

Help us further define the population dynamics of the rebound-competent HIV reservoir across a spectrum of individuals and determine how various therapeutic interventions affect reservoir composition over time. 

Help End the HIV Epidemic Through New Funding Opportunities

Three opportunities encourage applicants to consider creative, locally defined, and culturally sensitive concepts in pursuit of key strategies to end the HIV epidemic in the United States.

Address Neglected Tropical Diseases Through Global Research Collaborations

NIAID seeks collaborative, global research focused on the etiology, epidemiology, pathogenesis, clinical manifestations, diagnosis, prevention, treatment, and control of select neglected tropical diseases.

Harness the Energy of Innovation To Diversify Tuberculosis Vaccine Development

The initiative invites applications to discover and evaluate multiple novel vaccine candidates and diversify the current tuberculosis vaccine pipeline.

Act Now To CounterACT Chemical Threats

NIAID is now participating in four funding opportunity announcements related to the Countermeasures Against Chemical Threats (CounterACT) program.

Focus of New NOSI—Complement Components in Immune Responses

Study the roles of complement components that will inform the development of adjuvants and vaccine candidates or therapeutics that target complement components.

Get on TRAC With New Tuberculosis Funding Opportunity

Funding for Tuberculosis Research Advancement Centers (TRACs) will foster and enhance multidisciplinary collaboration across all aspects of tuberculosis research.

Opportunity for Early-Stage Investigators To Shift Research Direction

Through a new funding opportunity announcement, NIAID will fund innovative projects that represent a change of research direction for early-stage investigators and for which preliminary data do not exist. 

Apply for Funds to Develop Innovative, High-Impact HIV Vaccine Approaches

The initiative supports early discovery of novel exploratory vaccine strategies to prevent HIV infection, as well as worthy basic vaccine discovery research that has not yet been fully exploited.

Reissued Funding Opportunity Centers on ME/CFS

Collaborative research centers will help provide the foundation and infrastructure to complete basic, translational, and mechanistic clinical trials focused on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

We Want You to Develop Animal Models for Hepatitis B and C

In your application, describe plans to develop either small animal models or surrogate virus-host systems for hepatitis B virus or hepatitis C virus research.

Find Funding for Translational Research in Maternal and Pediatric Therapeutics

NIAID will support research to improve safe and effective precision therapeutics for pregnant and lactating persons, fetuses, neonates, and children, including those with disabilities.

Two Opportunities to Join NIH’s Centers for AIDS Research Network

The Centers for AIDS Research program fosters synergy and research coordination, supports emerging research opportunities, and promotes resource sharing among institutions that receive significant HIV/AIDS funding from NIH.

Investigate Vaccine Formulations with HIV Immunogens and Adjuvants

NIAID is soliciting contract proposals from offerors capable of providing a broad range of services to investigate vaccine formulations with HIV immunogens and adjuvants.

Administrative Supplement Supports Research Testing on Gender Measurement

The health conditions of interest to NIAID impact the health of sexual minority and majority populations, and the Institute endorses meaningful sexual orientation and gender identity measurement in research, clinical care, and administrative settings.

Check Out Career Development Opportunity for Early-Career Physician-Scientists

The Physician-Scientist Pathway to Independence Award is designed to increase and maintain the field of new and talented physician-scientists by supporting mentored research training and an independent research period.

New Solicitation Focuses on Development of Cellular Immunology Core

NIAID seeks a partner to operate the Cellular Immunology Core Laboratory, which will conduct, analyze, develop, optimize, and validate cellular immunologic assays for multiple pathogens, to be performed on fresh and frozen preclinical samples.

Apply to Study Complement System’s Role in Immune Function

Research the roles of complement components and receptors in the initiation, magnitude, maintenance, and quality of immune responses involved in pathogenic infections, vaccination, post-infection sequelae, autoimmunity, allergy, or transplantation.

Participate in the Cooperative Centers on Human Immunology Program

Conduct research on human immune system regulation and function to discover and characterize new principles of human immunology for preventing and treating infectious diseases, immune-mediated pathogenesis, and immune-mediated diseases.

Don’t Overlook Career Development Award for HIV/AIDS Scholars

Each award will provide 3 years of support for intensive research career development under a mentorship team with expertise in preclinical application of nonhuman primate HIV/AIDS models and translation of the results to clinical application in humans.

Discover Therapeutics to Eliminate HBV cccDNA From Infected Cells

Help NIAID advance research to identify new antivirals that can eliminate hepatitis B virus (HBV) and covalently closed circular DNA (cccDNA) from infected cells to effect a functional cure.

New NOSI Seeks HIV Cure Interventions

Through this notice of special interest (NOSI), NIAID seeks a better understanding of the decay dynamics of various virus-infected cell subsets following antiretroviral therapy initiation to better inform new cure strategies.

Consider New Opportunities for Child Health Outcomes Research

The Environmental Influences on Child Health Outcomes Program supports multiple, synergistic longitudinal studies of mothers and their children, from conception to early childhood.

Contract Solicitation Focuses on Enhancing MTB Lab Testing in NIAID Clinical Trials

The Mycobacterium tuberculosis (MTB) Quality Assessment Program will serve NIAID-sponsored and collaborating clinical trial networks and cohorts as well as individual grantees conducting research in and outside the United States.

New Funding Opportunities Center on Coordinating Centers

NIAID seeks to establish three distinct centers through cooperative agreements in the scientific areas of allergy and asthma; transplantation; and clinical data and safety management.

Help Address Persistent Signs and Symptoms of Lyme Disease

NIAID aims to support research that directly and specifically addresses possible mechanisms of persistent symptoms in Post-treatment Lyme Disease Syndrome.

Three Funding Opportunities for Regenerative Medicine Innovation Projects

Regenerative medicine researchers can apply to conduct clinical trial planning, an investigator-initiated collaborative study, or an investigator-initiated clinical trial.

Ease Educational Debt Through Loan Repayment Programs

You must be a doctoral-level clinician or researcher committed to conducting NIH-qualified clinical research. If NIH approves your application, we will repay up to $50,000 each year toward your qualified educational debt.

Five Funding Opportunities on Climate Change and Health

Investigators working in the areas of allergy or infectious diseases have a significant role to play in advancing research on the impact of climate change on human health.

Propose Multiple Approaches To Study Immune Response in HIV Vaccination

Generate omics data from clinical or experimental samples, leverage computational approaches to generate hypotheses from omics data, and test the hypotheses in experimental settings.

Opportunity for Mechanistic Research in Cancer Immunotherapy

Apply if your research could build foundational knowledge to improve strategies to predict, prevent, or ameliorate toxicities that arise as a consequence of immunotherapeutic regimens.

Conduct Innovative Research on Hepatitis B Virus Cure

Further our understanding of unique challenges impacting hepatitis B virus (HBV) and HIV co-infected hosts to advance discovery and development of novel HBV interventions.

Seek SEPA Funding To Educate Grades 12 and Below

The Science Education Partnership Award (SEPA) initiative supports skills development, research experiences, mentoring, curriculum or methods development, and outreach for younger students.

Apply for a Chance To Enhance HIV Reservoir Susceptibility

The initiative is primarily intended to support basic research that explores hypotheses about what happens inside HIV reservoir cells to avoid elimination and how to counteract those mechanisms.

RAPPS Contracts—Resources To Advance Pediatrics and HIV Prevention Science

NIAID seeks contractors to support preclinical HIV research, develop pediatric formulations, and advance next-generation HIV prevention and treatment products.

Research on COVID-19 Testing Among Underserved and Vulnerable Populations

Help address the urgent need for social, ethical, and behavioral implications research to understand and reduce barriers to and disparities in COVID-19 testing among underserved and vulnerable populations.

Three Supplement Opportunities for Data Science Research

Request funding for your active grant or cooperative agreement for artificial intelligence and machine learning (AI/ML), AI/ML data readiness, or biomedical software development.

Apply To Participate in Nonhuman Primate Transplantation Study Group

Propose research to facilitate clinical translation of safe and effective approaches to reduce or eliminate dependence on immunosuppressive drugs for long-term allograft acceptance.

Build Capacity To Research Bioethical Issues Using Supplementary Funding

Focus on ethical, legal, and social implications relevant to collaborative research on HIV/AIDS or its comorbidities, other infectious diseases including those transmitted by vectors, immunologic and allergic diseases, and organ transplantation; or the ethics of clinical trials and implementation science.

Trio of COVID-Related Opportunities Cover Variety of Research Priorities

Three initiatives cover distinct topics: pathobiological mechanisms of post-acute sequelae, pediatric COVID-19 and respiratory viral co-infection, and vaccine hesitancy among health disparities populations.

Apply for Research Funds To Accelerate Progress of Celiac Disease Research

NIAID will support research projects on celiac disease pathogenesis, including pathways of disease and tissue destruction, and the cause of intolerance to a component of food.

Take Advantage of Supplements for Research Continuity

Don't overlook two notices of special interest designed to sustain research projects through investigators' critical life events, like childbirth and adoption.

Find Funding To Help Increase Understanding of Protozoan Pathogens

NIAID aims to support basic and preclinical research to characterize persister stages in selected protozoan infections.

Find PCTAS Assistance for NIAID-Funded Primary Caregivers

Primary Caregiver Technical Assistance Supplements (PCTAS) help NIAID grantees support postdoctoral research scientists who are taking care of a child or sick family member by hiring a technician to fill in when the caregiver is away.

Join Systems Biology Centers To Model Human Pathogens

Propose research projects that integrate experimental approaches and computational modeling to test and validate hypotheses of significance to the infectious diseases field.

MOSAIC Program Funding Opportunities Promote Diversity

The Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) program supports individual postdoctoral career transition awards and institutionally-focused research education cooperative agreements.

Be AWARE of New Initiative To Study HIV Prevention in Women

NIAID will support innovative, flexible, scalable technology-mediated epidemiologic studies focused on identifying vulnerabilities and informing prevention and treatment of HIV in cisgender, transgender, and gender nonconforming women living in the United States.

New FOA Seeks To Expand Diversity in Extramural Scientific Workforce

The funding opportunity announcement (FOA) will support creative educational activities with a primary focus on courses for skills development, research experiences, and mentoring activities.

NIAID Funding Opportunity for COVID-19 Personal Protective Equipment

The new opportunity is the only available option to allow for the purchase of personal protective equipment totaling more than $500,000 in direct costs in a budget period.

New FOA for Ocular and Pulmonary Toxicity Research

There is an urgent unmet need to further understand the physiological mechanisms involved in the initiation and downstream events of injury after acute exposure to many chemicals identified as public health threats.

Apply for Funds To Promote Understanding of Skin Injuries Caused by Chemical Threats

Conduct fundamental research to identify potential shared signaling pathways and targets that may inform the development of broad-spectrum medical countermeasures.

Apply To Conduct Basic Science Research on Bunyavirales Pathogens

NIAID aims to develop a range of approaches for studying bunyaviruses using both established and novel technologies, prioritizing vector competence, virology and pathogenesis, and human innate and adaptive responses to infection.

Expand Emerging Science and Technology in Transplantation Through Cooperative Research

Participate in a cooperative research group focused on applying novel science and technologies to transplantation immunology in three priority areas: microbiota, intravital imaging, and targeted therapeutic delivery.

Identify Mechanisms Behind Heterogenous Influenza Response by Developing Computational Tools

Identify mechanisms behind heterogenous seasonal influenza infection responses by developing and applying computational tools; specifically, tools that can integrate molecular, genetic, cellular, patient, or population-level data.

Address Research Gaps in Radiation-Induced Immune Dysfunction

Apply for support to develop animal models for immune-targeted radiation injuries, study radiation impacts on the immune system, and identify immune-specific pathways targeted by radiation.

Join NIH’s Accelerating Medicines Partnership To Research Autoimmune Diseases

The program's overarching goal is to understand cellular and molecular disease pathways and identify novel targets for intervention among select autoimmune diseases.

A Trio of Data Science-Related Funding Opportunities

NIAID aims to promote research-driven data science/informatics technology, across their development lifecycle, in an effort to address priority needs in immune-mediated or infectious disease research.

Omnibus Contract Opportunity for Medical Countermeasures

The broad agency announcement supports three distinct scientific areas tied to biothreat agents, antimicrobial-resistant infections, and emerging infectious diseases.

Expand Basic Research of Non-Polio Human Enteroviruses

NIAID has issued a new funding opportunity announcement focused on non-polio human enteroviruses and future vaccine and therapeutic development.

Reissued Opportunity To Join the Human Immunology Project Consortium

Join a network of human immunology profiling research groups gathering data to develop molecular signatures that define immune response profiles and identify biomarkers.

Collaborate on Early Life Immune Development Research Through IDEaL Program

Apply to study immune system development and maintenance in children from birth to adolescence, including the impact of pathogenic or non-pathogenic microbes or vaccination.

Help Address Vaccine Hesitancy and Uptake Among Populations Experiencing Health Disparities

Apply for research funding to use scientific methods to address vaccine hesitancy, uptake, and implementation among groups experiencing health disparities.

Research Synthetic Nucleic Acid Platforms to Fight HIV

Propose research to apply newly developed immunological tools and expand understanding of the immune response to vaccination at the molecular level.

Resources for Sites Providing Diagnostic Services for Patients with Undiagnosed Diseases

Demonstrate that your clinical site has a track record of diagnosing rare and difficult-to-diagnose disorders, with appropriate expertise as well as the infrastructure and resources needed to conduct clinical evaluation and DNA sequencing of participants enrolled at your site.

Scrutinize Molecular Mechanisms Amid Suppressive Antiretroviral Therapy

NIAID aims to spur new approaches that target HIV transcription to shut down the expression of HIV RNA, proteins, and virus that occurs despite interruption of the viral life cycle by antiretroviral therapy.

Administrative Supplements for Climate Health, Software Tools, Data Readiness

NIH published three notices of special interest that each offer administrative supplements for ongoing research projects to further explore priority topics: climate health, software tools, and data readiness.

NIAID Solicitation Seeks Preclinical Animal, Animal-Replacement Models

Can your organization develop, refine, and use animal and animal replacement models to assess candidate therapeutics, vaccines, and diagnostics targeted at infectious diseases and generate difficult-to-source reagents requiring an in vivo model?

NIAID-Supported HIV Vaccine Trials Network Has New Specimens Available

The HIV Vaccine Trials Network (HVTN) invites outside investigators to apply to use Imbokodo/HVTN 705 participant specimens or study data to conduct independent scientific research. Respond by April 4, 2023.

Gain Support for Mentored Career Development Using Nonhuman Primate Models

By facilitating access to experienced mentors, relevant facilities, and protected time for training centered on nonhuman primate models, these awards will help early-career scientists address key issues in clinically relevant research areas.

Reissued Supplements Provide Support for Early-Career Continuity

The funds may be used to pay for computational services, supplies, equipment, and supported effort of additional scientific staff to sustain the research project while an investigator gives priority to a critical life event.

NIAID Funding Available for Coccidioidomycosis Vaccine Research

Apply for research funding to address gaps in Coccidioides basic research; develop tools and resources to support vaccine development; and develop and advance vaccines to prevent coccidioidomycosis.

New NOSI Stimulates Research Targeting Pathogens Within the Arthropod Vector

Our notice of special interest (NOSI) aims to stimulate multidisciplinary research that targets the pathogen within the invertebrate host to prevent its transmission to the vertebrate host.

Opportunity to Establish Consortium for Design of TB Drug Regimens

The Consortium will establish a collaborative, multidisciplinary research platform to systematically evaluate new candidate agents in combination and identify the most promising regimens.

Administrative Supplements for Women’s Health Research in U3 Populations

The Notice of Special Interest encourages rigorous interdisciplinary research on the complex intersection of women’s health, sex and gender, and social determinants of health.

Research Resource Program Supports Laboratory of Developmental Biology

The initiative aims to foster an understanding of underlying developmental biology of normal and abnormal human development as well as human pathologies through collecting, identifying, staging, and distributing conceptal tissues for use in studies.

Foster Research on Health of Bisexual and Bisexual+ People

NIAID and other NIH institutes and centers aim to foster health research training and career development on the health and wellbeing of people who identify as bisexual or bisexual+.

Apply for Research Funds to Develop Multipurpose Prevention Technologies

NIAID seeks multipurpose prevention technologies (MPTs) that can prevent HIV infection and pregnancy; sexually transmitted infections (STIs) and pregnancy; or multiple non-HIV STI or HIV/STI MPTs in cis and trans males and females of all ages.

Develop Therapeutics as Countermeasures Against Chemical Threats

Develop therapeutics and medical countermeasures that mitigate the adverse health effects of toxic chemical exposure, including validation of therapeutic targets and preclinical characterization of lead compounds.

Apply To Study Molecular Dynamics of HIV Through Existing Datasets

NIAID seeks studies to provide integrated structural, computational, and functional approaches to understanding the dynamics of key molecular processes in the HIV life cycle.

Research Immunity, Preventions, and Treatment of HIV and STIs in Transgender People

Apply to conduct research on biological and immunological factors that contribute to HIV and sexually transmitted infections in transgender people.

Accelerate Research on Tickborne Illnesses Through Admin Supplements

NIAID will accept administrative supplement applications from current NIAID awardees for research on Lyme disease or other tickborne illnesses, including alpha-gal syndrome.

NIAID Contract Opportunity To Develop a Novel Vaccine Adjuvant

NIAID will support the preclinical development of lead adjuvants for use in vaccines to prevent or treat human disease caused by non-HIV infectious pathogens or immune-mediated diseases.

Submit Applications To Improve Drug Susceptibility Testing for Tuberculosis

Help improve treatment decisions for patients by honing drug susceptibility testing methods and thus reduce rates of drug-resistant tuberculosis in the community.

Conduct Research To Bolster Bacteremia and Hospital-Acquired Pneumonia Testing

NIAID will support investigators developing or producing medical diagnostics capable of rapid differential species identification and phenotypic antibacterial susceptibility profiles for bacteremia or hospital-acquired pneumonia.

Administrative Supplements Designated for Outstanding Mentors

What does it take to develop exceptional scientists of the future? Two critical factors: excellent mentorship and superior training. To recognize the crucial role great mentors play, NIH will support supplements for excellence in mentorship.

An Opportunity To Train Clinicians To Be StARR Investigators

The program will provide up to two years of support for research conducted by resident-investigators in structured programs for clinician-investigators with defined program milestones.

“REAP” the Benefits of Reissued FOA for Research Experiences

The Research Enhancement Award Program (REAP) is for faculty members at eligible health professional schools and graduate schools. They can receive support for small-scale research projects that provide research experiences to undergraduate or graduate students pursuing biomedical or behavioral research.

Join the Asthma and Allergic Diseases Cooperative Research Centers Program

The program supports clinical and translational research on asthma, rhinitis, chronic rhinosinusitis, atopic dermatitis, food allergy, and drug allergy.

Funding To Coordinate International TB and TB/HIV Research

Coordinate and accelerate tuberculosis (TB) and TB/HIV research across all of the RePORT national networks and foster a synergistic approach among them. 

Volunteer To Annotate Immune Signatures Related to COVID-19

The Human Immunology Project Consortium is curating immune signatures related to COVID-19 from published literature to enable researchers to easily access and interrogate published immune signatures related to COVID-19 infection, vaccination, and immune response.

Propose Research Using Mouse Models To Understand Human Immunity

Propose to characterize immune system development, regulation, and function in mice with diverse microbial exposure through comparison to mice maintained under standard specific pathogen-free conditions.

Check Out Diversity Supplements for Small Business Grantees

While staying within the scope of the original project, small business grantees may use supplement funds to enhance the diversity of the research and entrepreneurial workforce.

Joint NIH/NSF Opportunity Seeks Transformative Advances Using Data Science

The funding initiative centers on developing transformative and translational advances in computer and information science, engineering, mathematics, statistics, and behavioral and cognitive research.

Talk About TABA for Small Business Commercialization

NIH’s Technical and Business Assistance (TABA) program helps small business awardees identify and address their most pressing product development needs and boost commercialization efforts.

Propose a Partnership for Tuberculosis Research in Brazil

Propose research topics involving tuberculosis in the areas of molecular epidemiology, diagnostics, biomarkers, and vaccine development, as well as the impact of co-morbidities such as HIV and diabetes.

Understand the Role of DEAD/H-box Helicases in Immune Homeostasis and Activation

NIAID encourages innovative research to provide foundational knowledge for understanding the role of DEAD/H-box helicases in innate immune sensing, antimicrobial immunity, inflammation, and immune cell homeostasis.

Study Innate Immune Memory Impacting HIV Acquisition

NIAID is interested in supporting research that can inform protective vaccine strategies that engage, enhance, and extend innate immune cell effector functions without causing harm.

NIAID Contract Opportunity for Structural Biology of Infectious Diseases

NIAID anticipates making two cost-reimbursement type level-of-effort contracts to implement the Centers for Research on Structural Biology of Infectious Diseases program.

July Deadline To Apply for Foreign Grant Administrators Training Support

The initiative supports senior administrators training to serve as institutional grants management leaders by supporting administrative staff in developing and implementing standard operating procedures.

Vaccine Adjuvant Compendium—Resource To View and Submit Adjuvant Metadata

NIAID’s Division of Allergy, Immunology, and Transplantation and Office of Cyber Infrastructure and Computational Biology launched the Vaccine Adjuvant Compendium to foster collaborations between NIAID-supported adjuvant researchers and the broader scientific community.

Consider a New Bi-Phasic, HIV-Related Funding Opportunity

Contribute to the understanding of post-transcriptional regulation of intact and defective HIV RNA, and develop therapeutic strategies to alter RNA post-transcriptional modifications as a potential therapeutic platform for inhibiting HIV replication.

Check Out NOSI To Characterize Inborn Errors of Immunity

Conduct research that leads to a deeper understanding of the causes and mechanisms of disease of inborn errors of immunity, enables early detection, and develops strategies to treat and cure these disorders.

New Initiative To Support Studies of the Bat Immune System

Understanding the mechanisms of how bats regulate immune responses to clear infections and prevent excessive inflammation may lead to a deeper understanding of the regulatory circuitry of the human immune system and host-pathogen interactions.

Improve Maternal Health Outcomes Through Innovative Small Business Initiatives

NIAID encourages the small business community to develop various approaches, technologies, and tools to address the health issues of maternal morbidity and mortality.

Notice of Special Interest for COVID-19 U01 Applications Expires in March

NIAID's notice of special interest Availability of Emergency Awards for Limited Clinical Trials To Evaluate Therapeutic and Vaccine Candidates Against SARS-CoV-2 will expire on March 15, 2021, meaning the deadline to apply is March 14, 2021.

Contract Funds for Clinical Pharmacology Quality Assurance

The request for proposals seeks an offeror capable of providing quality assessment for pharmacology labs that test samples from NIAID-supported clinical studies.

Extended Deadline for Characterization of HIV Vaccine Formulations BAA

NIAID has extended the application deadline for the broad agency announcement (BAA) Rational Systematic Characterization and Selection of Adjuvants for HIV Vaccine Candidates; proposals are now due on July 7, 2023, at 4 p.m. Eastern Time.

Leverage Your Expertise Towards Genomic Centers for Infectious Disease Program

Help us develop and advance approaches in genomic technologies, computational tools, and large-scale data analysis of human pathogens and their interactions with the host and microbiome.

Opportunity to Join the Autoimmunity Centers of Excellence

Combining Basic and Clinical research programs, the objectives of NIAID's Autoimmunity Centers of Excellence are to accelerate the discovery and translation of therapies for autoimmune diseases from lab to clinic.

Find Funding to Study Sexual and Gender Minority Health

Your research should lead to the development of acceptable and appropriate health interventions and health service delivery methods that will enhance health and development of sexual and gender minority populations.

Keep Tabs on TABA for Small Business Commercialization

NIH’s Technical and Business Assistance (TABA) program helps small businesses identify and address pressing product development needs and boost commercialization efforts.

Develop HIV Therapeutic Products Using NIAID Preclinical Services

Investigators may submit short applications to request and justify access to a discrete set of preclinical services provided by NIAID contractors at no cost to the applicants.

Apply Now for U.S.-India Fellowship Exchange Program

A fellowship exchange program for early- and mid-career scientists aims to expand the cohort of physician-scientists that will advance clinical practice and public health in the United States and India.

NIAID Funding Available for Biocontainment Facility Improvements

NIAID will sponsor facility improvements and building systems upgrades at existing biosafety level 3 and biosafety level 4 laboratories engaged in research on RNA viruses of pandemic potential.

Clinical Researchers—Apply To Be a Lasker Scholar

Exceptional early-stage clinical researchers will receive five to seven years of support within the NIH Intramural Research Program as tenure-track investigators followed by continued intramural funding or a supported transition to an extramural institution.

Still Time To Apply For Administrative Supplements on Women’s Health, Sex and Gender

Applications are due for three distinct initiatives providing administrative supplements for research at the nexus of women’s health, sex and gender, and health disparity populations.

Apply To Form an Analysis and Bioinformatics Center for SUNBEAM

Provide analytic infrastructure to comprehensively understand molecular and cellular pathways that contribute to atopic disease development and to identify early predictive biomarkers.

Funding Opportunity To Detect and Report HIV-1 Drug Resistance Mutations

If you have the expertise to develop or optimize next-generation methodologies to detect HIV-1 drug resistance mutations and rapidly disseminate the information, consider applying for research funding.

Pursue Strategies To Provide HIV PrEP and ART in STI Service Settings

NIAID will support research to design and evaluate strategies for reducing HIV incidence by scaling up pre-exposure prophylaxis (PrEP) and antiretroviral treatment (ART) in sexually transmitted infections (STI) service settings.

Funding for Early-Stage Investigators Doing Exploratory Research on Chemical Countermeasures

Early-stage investigators can find support for exploratory, applied, proof-of-principle, or high-risk, high-impact research projects to discover safe and effective therapeutics to mitigate toxicities resulting from exposures to highly toxic chemicals.

Find Funding for Research on HIV Broadly Neutralizing Antibodies

Find funding to characterize mechanisms that impact resistance to HIV broadly neutralizing antibodies (bNAbs) and develop strategies to prevent and overcome HIV resistance to bNAbs.

Start Planning for HIV Structural Biology U54 Funding Opportunity

Prepare now to join the Centers for HIV Structural Biology, which integrate techniques from structural biology, biochemistry, and cell biology to ultimately solve the three-dimensional structures of HIV and host cell factor complexes necessary for viral replication.

NIAID Solicitation Invites Proposals for Early-Phase Clinical Trial Units

NIAID seeks offerors capable of implementing Phase 0 to Phase II clinical trials, including proof-of-concept studies in healthy and diseased human populations—domestically and internationally—in an expeditious and efficient manner.

Supplements Available for DEIA Mentorship, Bioethics-Related Research

Two new initiatives recognize the role that diversity, equity, inclusion, and accessibility (DEIA) mentorship and bioethical research and capacity, respectively, have on NIH’s general scientific priorities, like responding to public health needs.

Funding for Research on the Uptake of Health Interventions

Identify, develop, or test strategies to overcome barriers to dissemination and implementation of evidence-based interventions into public health, clinical practice, and community settings.

Nonhuman Primates Funding Opportunity Adds AIDS Receipt Dates

Applicants submitting AIDS-related research applications for a funding opportunity on using nonhuman primate models in basic science or translational research have new receipt dates to follow.

SuRE—Build Research Capacity and Support Underrepresented Students

Support for Research Excellence (SuRE) grant funds can help build research capacity, develop and sustain research excellence, and provide research experience to students from groups that are underrepresented in biomedical science.

Take Note of New Data Science-Related NOSIs

Find funding to prepare your data assets to meet technical specifications for inclusion in the NIAID Data Ecosystem and improve training among biomedical, behavioral, clinical, and computational scientists for research on infectious and immune-mediated diseases.

Find Funds for Biomedical Informatics and Data Science Training Programs

Mentors, apply for a grant to support predoctoral and postdoctoral training for research careers in biomedical computing, data science, and other information fields.

In The News

NIAID Posts Final FY 2023 Paylines for R01, R15 Grants

NIAID sets a separate R01 payline for new and early-stage principal investigators (PIs) to ensure success rate parity between established and new and early-stage PIs.

DEIA Prize Competition Offers $100,000 for Inclusive Excellence

NIH aims to recognize the transformative cultures, systems, projects, and processes developed by academic institutions to promote inclusive excellence and create environments that foster and value a culture of diversity, equity, inclusion, and accessibility (DEIA).

Seeking Input on NIAID’s DEIA Request for Information

What are the gaps and barriers to developing, diversifying, and sustaining a diverse extramural scientific workforce and building a scientific pipeline to support the NIAID mission?

NIAID Paylines and Budget Data Updates from March 2023

Use the Budget Data Comparisons table to compare the enacted funding levels for fiscal years 2022 and 2023 across multiple NIH institutes and centers, including NIAID. 

A Checklist to Recount Study Design for Vertebrate Animal Research

Heed NIH's call to improve complete reporting of results of vertebrate animal and cephalopod experiments by using the Animal Research: Reporting of In Vivo Experiments checklist.

Salary Cap and NRSA Stipend Levels Announced in Early 2023

Congress restricts the amount of direct salary paid to an individual under an HHS award. Effective January 1, 2023, the salary limitation is set at a rate of $212,100 for 100 percent effort.

Summary of January 2023 Advisory Council Meeting

NIAID Acting Director Dr. Hugh Auchincloss provided updates on HIV/AIDS, malaria, Ebola, a promising Marburg vaccine, universal flu vaccine efforts, non-viral asthma attacks, monoclonal antibodies to target Epstein-Barr virus, and human antibody response to vaccinations.

December’s ACD Meeting—Featuring Bill Gates and Dr. Anthony Fauci

NIH’s Advisory Committee to the Director (ACD) provides recommendations on program development, resource allocation, NIH administrative regulation, and other aspects of NIH policy.

Provide Input on Proposed Simplified Review Framework for NIH Research Project Grant Applications

The Revised Simplified Review Framework would reorganize five major regulatory criteria under three scored categories and reduce the number of non-score driving review considerations that reviewers evaluate.

Get Ready for the February 2023 NIH Virtual Grants Conference

Engage with NIH staff through questions and answers, text chat features, and 1:1 calls. With over 15,000 attendees already registered, you will also have plenty of networking opportunities to meet colleagues in your field.

Dr. Anthony Fauci to Leave NIAID at the End of December

At the end of this month, Dr. Anthony Fauci, Director of NIAID, will step down from the role he’s held since 1984.

NIH Posts Resources in Preparation for FORMS-H Transition

For applications due on or after January 25, 2023, you must use the FORMS-H application form set rather than the FORMS-G application form set.

More Interim Paylines and Budget News for Fiscal Year 2023

An interim payline is an administrative measure that allows us get some top-scoring grants out the door while we wait for our appropriation.

Administrative Changes to Microbiology and Infectious Diseases Study Sections

NIH's Center for Scientific Review regularly assesses whether the function and scope of existing panels result in successfully identifying high-impact science before making administrative adjustments.

Initial Interim R01 Paylines Posted for Fiscal Year 2023

We are starting fiscal year 2023 under a continuing resolution, which will run through December 16, 2022. Our budget officials are now calculating appropriate interim payline levels.

Don’t Let Dollars Expire Upon Payment Management System Drawdown

Grantees, take note: You have 120 days after your grant’s period of performance end date to liquidate obligations by drawing funds from the Payment Management System.

Save the Dates—2023 NIH Grants Conference and 2022 Events

A new PreCon webinar series gives you multiple opportunities to learn about grant processes and policies, engage with NIH experts, network with your peers, and gather information to use and share.

Grants.gov Downtime Will Impact Application Due Dates in September

The Grants.gov web system will undergo downtime from September 23 to September 29, 2022. In response, all NIH grant application due dates that fall on or between September 22 and September 30 will shift to October 3, 2022.

Invention Reporting System iEdison Will Transition to NIST Next Week

iEdison, the electronic system that recipients use to report inventions and patents resulting from federal research, will transition from NIH’s eRA to the National Institute of Standards and Technology (NIST) on August 9, 2022.

Check Out New NIAID Guidance on Responsible Conduct of Research

Fellowship, career development, institutional training, and research education grant applicants, NIAID's guidance page can help you plan instruction on responsible conduct of research for curricula and applications.

Eligibility as a Small Business Concern Isn’t Fixed

If a legal action changes the status of a small business concern such that it no longer meets NIH’s eligibility parameters, the organization may not receive additional small business funding.

NIAID Posts Final FY 2022 Paylines for Most Award Types

We’ve set final paylines for research project grants, fellowship awards, career development awards, and small business grants for fiscal year (FY) 2022.

Awardees Must Report Harassment-Related Disciplinary Actions

Awardee institutions must notify NIH after acting to remove or discipline key personnel due to concerns about harassment, bullying, retaliation, or hostile working conditions.

COVID-19 Exception—Post-Submission Materials for January 2023 Council Rounds

An exception to allow applicants to send one page with preliminary data as post-submission materials will remain in effect for applications submitted for the January 2023 Council rounds.

iEdison Transitioning to NIST This Summer

The system award recipients use to report inventions and patents resulting from federal research will be transitioning from NIH’s eRA to the National Institute of Standards and Technology (NIST).

Paylines Page Updated for Research Project, Small Business Grants

Paylines—either percentiles (R01s only) or overall impact score order—are the funding cutoff points for investigator-initiated applications. 

A Special Thank You to AViDD Peer Reviewers

Reviewers committed unusually high levels of effort in a short time to help NIAID identify and fund key research on innovative antiviral drug development targeting coronaviruses and other select RNA viruses.

Give Feedback on CSR’s Plan To Strengthen Peer Review

Send feedback on the Center for Scientific Review's (CSR) new Strategic Plan to advance its mission of ensuring that NIH grant applications receive fair, independent, expert, and timely scientific reviews.

Peruse NIAID’s New Pandemic Preparedness Plan

Selecting representative viruses from each virus family offers a viable pathway to gain knowledge as well as develop and test candidate countermeasures that may apply to part or all of a particular virus family.

Beta Version of ClinicalTrials.Gov Enhances User Efficiency and Experience

NIH’s National Library of Medicine introduced a new beta version of ClinicalTrials.gov, a website and online database providing clinical research studies and results to the public, researchers, and healthcare professionals.

Review Changes to NIH Grants Policy Statement for Fiscal Year 2022

NIH published a revised Grants Policy Statement (GPS) for fiscal year 2022. The NIH GPS provides policy instruction that serves as the standard terms and conditions of award for NIH grants, as well as guidance for applicants pursuing an NIH grant.

Send Feedback To Help Untangle a Genomic Data Sharing Policy Knot

NIH will soon adjust the Genomic Data Sharing policy to better align with expectations set by the new Final Policy for Data Management and Sharing policy.

Be Aware of CDC’s Interim Final Rule on SARS-CoV/SARS-CoV-2 Chimeras

CDC added the following to the list of HHS select agents: SARS-CoV/SARS-CoV-2 chimeras in which SARS-CoV (already a select agent) virulence factors have been inserted into SARS-CoV-2 (not a select agent).

Conducting a Clinical Trial? Prepare for Revised Progress Report Validations

NIH implemented updated eRA Research Performance Progress Report submission system validations for clinical trial registration and results reporting.

Summer Application Totals Give Clues to Pandemic Productivity

The extramural community collectively wrote and submitted a higher volume of research project grant applications amid pandemic shutdowns in summer 2020.

Other Transactions—An Introduction

Other transactions are a special type of legal instrument other than a contract, grant, or cooperative agreement.

Good News—Trainees Can Receive Childcare Support

Full-time predoctoral and postdoctoral institutional National Research Service Award-appointed trainees with children can now receive $2,500 per budget period for childcare costs provided by a licensed childcare provider.

Preview the 2021 NIH Virtual Seminar on Program Funding and Grant Administration

Whether you’re new to NIH awards or have years of experience, the Virtual Seminar is your unique opportunity to learn, share, and meet with NIH and HHS experts as well as your peers from across the globe.

For sIRB Applications, Tell Us You Have a Plan

For nonexempt human subjects research using a single protocol at multiple U.S. sites, you must identify a single institutional review board (sIRB) of record that will conduct the ethical review of your protocol.

NIH Announces FORMS-G Transition, Implementation Plans

This fall and winter, there will be stretches of time in which you can select between the FORMS-F and FORMS-G application form sets within the same FOA. You'll need to choose correctly, as NIH may withdraw an application submitted using the wrong form set.

NIH Shares Applicant, Awardee Counts for Early-Stage Investigators

NIH strives to address longstanding challenges faced by researchers trying to embark upon and sustain independent research careers, as well as promote the stability and diversity of the biomedical research workforce. 

Don’t Miss the Educational Loan Repayment Programs

To be eligible, you must be a doctoral-level clinician or researcher who’s committed to conducting NIH-qualified research. If NIH approves your application, you receive up to $50,000 each year toward your qualified educational debt.

Postdocs—Eligibility Extended for K22 and K99/R00 Due to COVID-19

You may have a temporary extension to your eligibility for NIAID Career Transition Awards (K22) and NIH or NIAID Pathway to Independence Awards (K99/R00).

Recap of June’s Advisory Council Meeting

NIAID Director Dr. Anthony Fauci discussed topics like budget and legislation, and Dr. John Mascola, director of the Vaccine Research Center (VRC), described VRC's work on mRNA and therapeutic antibodies related to COVID-19 as well as on influenza vaccines.

New Formats and Instructions for Other Support and Biographical Sketches

Use NIH’s new biographical sketch and other support formats and instructions for your applications, preaward submissions, and progress reports. The updated formats and instructions are optional now and will become a requirement on January 25, 2022.

Stream NIH Research Summit on Anti-SARS-CoV-2 Antibodies

Presenters will summarize current knowledge and lessons learned on clinically relevant anti-SARS-CoV-2 antibodies for treating or preventing COVID-19 and identify key unanswered scientific questions for clinical development and implementation.

NIAID Sets Parameters for F and K Awardees To Request Funded Extensions

NIAID may provide funded extensions to current fellowship (F) and career development (K) award recipients who have experienced significant hardship and are in the final year of their award’s period of performance.

HHS Removes an Administrative Requirement for Human Fetal Tissue Research Proposals

Effective immediately, HHS no longer requires review and approval by an ethics advisory board for research proposing to use human fetal tissue.

NIH Survey Asks About Pandemic Impact on Biomedical Workforce

NIH surveyed researchers and administrators to gain a greater perspective of how the COVID-19 pandemic disrupted and burdened the biomedical research workforce.

NIH Center for Scientific Review—Standing UNITEd

As part of UNITE, an NIH initiative to end structural racism in biomedical research, the Center for Scientific Review continues to take steps to address individual and systemic biases in peer review.

NIH Will Provide Support to NRSA Fellows for Childcare Costs

Effective April 8, 2021, NIH will provide childcare support to recipients of NRSA fellowships. Each fellow is eligible to receive $2,500 per budget period toward expenses for childcare provided by a licensed childcare provider.

Summary of Salary Cap and Stipend Levels for Fiscal Year 2021

Learn about the fiscal year 2021 salary cap and stipend levels for National Research Service Awards that NIH published in January.

NIAID Peer Review and Committee Volunteers Deserve Thanks

On behalf of NIAID and our research community, we gratefully acknowledge all the peer reviewers and advisory committee members who gave their valuable time and effort this past year. You make an irreplaceable contribution to biomedical science.

Budget Updates From January 2021 NIAID Advisory Council Meeting

Learn more about NIH’s $42.9 billion appropriation for fiscal year 2021, which is an increase in NIH’s overall budget of $1.25 billion over the fiscal year 2020 level.

Submit Collaborative Proposals for Infectious Disease and Immunology Research Awards

Submit a proposal centered on questions directly related to the Asia-Pacific region with potential to add to global knowledge about infectious diseases and immunology.

Lasker Program—Join NIH as a Clinical Researcher

NIH will employ and support up to five exceptional early-stage investigators who have not yet achieved tenure at a research institution.

Coming June 2023—Modernized ClinicalTrials.gov Website

The National Library of Medicine based ClinicalTrials.gov modernization efforts on user feedback to improve how visitors search, view, and download information about clinical trials.

A Rule Change for Preliminary Data as Post-Submission Materials

NIH will allow applicants to submit preliminary data as post-submission materials for new applications (Type 1) if the notice of funding opportunity uses the R01, R03, or R21 activity codes and allows preliminary data.

Understand the Peer Review Process to Inform Your Next Application

You may be able to anticipate which standing review group and primary reviewers are most likely to review your application, then write to fit your reviewers' areas of scientific focus and levels of understanding.

Provide Feedback to Help NIH Evaluate Postdoctoral Research Training

Share your thoughts on the roles and responsibilities of academic postdocs, including challenges in recruitment, retention, and quality of life of postdoctoral trainees.

Contribute to NIAID’s Efforts on Diversity, Equity, Inclusion, and Accessibility (DEIA)

NIAID invites information and recommendations to enhance DEIA across the Institute’s funded activities, such as strategies to address any systematic and structural barriers to receiving NIAID research funding that may exist.

NIAID Updates Interim R01, R03, and R21 Paylines

NIAID uses paylines as funding cutoff points for certain types of investigator-initiated grant applications. Last week, NIAID updated the interim paylines for research projects (R01), small grants (R03), and exploratory/developmental grants (R21).

NIH Announces Revisions to NIH Grants Policy Statement for Fiscal Year 2023

The NIH Grants Policy Statement provides up-to-date policy instruction that serves as the standard terms and conditions of award for NIH grants, as well as guidance for applicants pursuing an NIH grant.

Don’t Miss Your Chance to Showcase Small Business Projects

The initiative is part of NIH's comprehensive approach to help small business innovation research and small business technology transfer grant recipients commercialize healthcare technologies and services.

Novel Fellowship Opportunity to Open for Applications Soon

NIH Medical Scientist Partnership Program scholars will complete their clinical degree training at their desired clinical degree school and conduct the PhD portion of their training in research laboratories in the NIH Intramural Research Program.

New Option to Bypass Viewing Window for Administrative Supplements

To expedite processing of eligible administrative supplement requests, NIH now offers an option for signing officials to bypass the standard 2-business day application viewing window.

November 17 Deadline for Loan Repayment Program Applications

NIAID participates in four Loan Repayment Programs, specifically those for clinical research, pediatric research, health disparities research, and research in emerging areas critical to human health.

NIH Policy for Data Management and Sharing—New Supplemental Information

To help researchers address privacy considerations when sharing human research participant data, NIH issued two notices that supplement the new Data Management and Sharing Policy.

Your Data Sharing Plan—How GDS and DMS Policies Will Interact

For applications due on or after January 25, 2023, you should create a single Data Management and Sharing Plan that incorporates your genomic data sharing plans for the project.

New Research Sharing Policy to Speed Access to Results

As directed by the White House, NIH will revise its public access policy to enable researchers, clinicians, students, and the public to access research results immediately upon publication.

Review and Correct FY 2022 Grant Information by October 3

Grantee organizations should review and verify the accuracy of their grant assignments for Departments or Components within Organizations of Higher Education in eRA Commons.

FORMS-H Will Implement New Data Management and Sharing Policy

For receipt dates on or after January 25, 2023, grant and cooperative agreement applicants must provide data management and sharing plans as a standard requirement of the new FORMS-H application form set.

Review Group Roster Index—New Look, New Options

The Roster Index lists past and present study sections, integrated review groups, and special emphasis panels. eRA’s update provides options to filter the table of review groups, export, and print.

NIH Charts Trends in Research Project Grant Costs Over Time

Review data that show NIH has increased the number of research project grant awards in recent years, despite increases in nominal costs due to inflationary pressures.

NIH and NIAID Staff Assess Peer Review Service Time

Our scientific review officers often seek reviewers for Special Emphasis Panels to score grant applications or contract proposals submitted in response to NIAID’s solicited funding initiatives and programs.

Provide Feedback on Promoting Equity in Global Health Research

Help improve NIH’s understanding of potential research funding, priority setting, administrative practices, and strategies that could encourage or facilitate equitable global health research.

Provide Comments on Flexibilities for Semiannual Animal Program Reviews

Submit feedback to help NIH’s Office of Laboratory Animal Welfare gather input on flexibilities available to Institutional Animal Care and Use Committees conducting semiannual reviews.

Identify Challenges and Opportunities in Health and Science Communication Research

NIH seeks input from the broader scientific research community on opportunities, challenges, methods, approaches, and technologies to enable the future study of health and science communication.

Explore a New Look for eRA’s Website

Although the website has a new homepage layout and labels some sections differently, rest assured that eRA’s guidance for applicants, grantees, and reviewers remains unchanged.

Comment on the Link Between Women’s Health and the COVID-19 Pandemic

Comment on research gaps, clinical practice needs, and research priorities at the intersection of women’s health concerns and SARS-CoV-2 infection, COVID-19 illness, and post-acute sequelae of SARS-CoV-2 infection.

Send Feedback To Inform NIAID’s Approach to Sex Differences in Radiation Research

We hope to gain insight into the current research landscape on sex differences in radiation injury, and specifically learn about challenges and gaps in the field.

Provide Comments on Managing and Sharing American Indian/Alaska Native Participant Data

NIH seeks input on draft Supplemental Information to the NIH Policy for Data Management and Sharing (DMS Policy) to promote responsible management and sharing of American Indian/Alaska Native participant data under the DMS Policy.

Send Comments on Research and Vaccines for Coccidioidomycosis

NIAID invites community and stakeholder feedback on a strategic plan to advance research and development of a vaccine for the fungal infection coccidioidomycosis.

Collaborate With CEIRR on Influenza Research

Create an innovative influenza research proposal that advances the NIAID mission of pandemic preparedness and response, and aligns with the goals and unmet needs of one of the Centers of Excellence for Influenza Research and Response.

NIH Invites Feedback To Shape Scientific Workforce Diversity Strategic Plan

The draft Strategic Plan outlines three goals—to build, disseminate, and act on empirical, data-driven evidence to advance scientific workforce diversity—as well as how to leverage corresponding objectives and tactics to achieve each of these goals.

Comment on NIH’s Research Plan To Cure Hepatitis B

Send suggestions and feedback on NIH's Plan to improve understanding of hepatitis B biology, develop tools and resources, and create hepatitis B cure and prevention strategies.

Dive Into the 2021 NIH Virtual Seminar Archive

You can access videos, slide sets, and transcripts from dozens of seminar session presentations from the 2021 NIH Virtual Seminar on Program Funding and Grants Administration.

Identify Ferret and Hamster Immunoreagents for Project Planning

NIAID seeks feedback from the research community to help us assess high-priority needs for immunoreagents (specifically, monoclonal antibodies and aptamers) against ferret and hamster antigens.

Clarifying Animal Protocol Congruence Reviews for Grants and Contracts

Before award, your recipient institution must verify that your institutional animal care and use committee has reviewed and approved the components of your application or proposal related to the care and use of animals.

Register for NIH Seminar on Determinants of Rural Health Disparities

The event will raise awareness of rural health issues and enhance biomedical, behavioral/social science, intervention, and implementation research to improve rural health outcomes.

Participate in NIH Assessment of Health Disparities Research Landscape

The NIH Common Fund will host a Virtual Community Listening Sessions Series to better understand the opportunities, challenges, and community needs surrounding interventions that target social factors that influence health.

Join NIAID Workshop on Pandemic Preparedness and Prototype Pathogens

As part of the workshop, NIAID will request feedback from the scientific community on identifying and prioritizing prototype pathogens within viral families of highest pandemic potential for the development of medical countermeasures.

NIH Natural Disaster Policy Applies to Recent Hurricanes

NIH will consider accepting applications after a submission deadline from investigators whose institutions close due to a natural disaster, such as the recent hurricanes Henri and Ida.

Organization ID Numbers Set To Change This Winter

Federal electronic systems will soon transition from using DUN and Bradstreet Data Universal Numbering System identification numbers to new government-owned Unique Entity Identifiers.

OLAW Seeks Input on Clarifying IACUC Reporting Requirements for Guide Departures

Send feedback to inform NIH clarifications of Institutional Animal Care and Use Committee (IACUC) reporting requirements for departures from the Guide for the Care and Use of Laboratory Animals.

More Resources for Prospective Applicants to AViDD FOA

Investigators, if you are interested in applying to the Antiviral Drug Discovery (AViDD) Centers for Pathogens of Pandemic Concern funding opportunity announcement, check out a pair of online resources before writing your application.

Webinars To Cover Antiviral Drug Discovery Centers FOA

If you’re considering applying, tune in for either of two webinars scheduled for July 23 at 9 a.m. Eastern Time, and July 26 at 12 noon Eastern Time.

Look for a New FOA Seeking Multidisciplinary Antiviral Drug Discovery Centers

A new funding opportunity announcement (FOA) will fund multiple research centers focused on innovative antiviral drug development targeting coronaviruses and one or more select RNA viruses with pandemic potential.

Provide Input on Radiation Exposure and Microbiome for Targeted Therapeutics

NIAID requests input from the radiation biology and microbiome research communities on the science of the interplay between radiation exposure and the microbiome, with an eye toward targeted therapeutics.

Bridge2AI Program Launches With Funding Opportunities, June Event Series

The Bridge to Artificial Intelligence (Bridge2AI) program aims to propel biomedical research forward by setting the stage for widespread adoption of artificial intelligence and machine learning to tackle complex biomedical challenges beyond human intuition.

eRA Commons ID Requirement Extends to All Senior/Key Personnel in January 2022

If you are planning an application due on or after January 25, 2022, take note that all senior/key personnel must have an eRA Commons ID. While all senior/key personnel have been encouraged to obtain eRA Commons IDs, it has not yet been required.

Take Training on Sex as a Biological Variable

When conducting vertebrate animal or human studies, you must follow the NIH Policy on Sex as a Biological Variable to increase the scientific rigor of your research.

Still Time To Answer RFI on Structural Racism and Workforce Diversity

The request for information (RFI) seeks community feedback on matters related to workforce diversity and inclusion, policies that create racial disparities, research gaps in the science of health disparities, and ideas for new approaches.

Three Updates From Rapid Acceleration of Diagnostics Initiative

NIH launched the Rapid Acceleration of Diagnostics initiative to quickly develop, commercialize, and implement technologies for COVID-19 testing. You can now view a list of funded projects.

Clinical Trial Applicants—Determine Level of Risk

Knowing whether your planned clinical trial is high-risk or not will help you decide the funding opportunity announcement through which you should apply.

NIH’s COVID-19 Website Shares Vaccine News and Clinical Trial Resources

Check out this NIH website for the latest COVID-19 research findings, clinical trial volunteer guidance, grant funding data, and vaccine/ treatment news.

Virtual Review Meetings Are Virtually the Norm at NIAID

Over the past 10 years, NIAID's Scientific Review Program has moved from primarily face-to-face peer review meetings to mostly teleconference and videoconferencing.

Send Feedback To Inform NIAID’s Approach on Key Immunologic Events in Autoimmune Diseases

NIAID seeks comments from the scientific community about state-of-the-art sampling and analysis techniques to identify key immunologic events underlying the onset, flare, remission, and progression of autoimmune diseases.

Change of Platform for Federal Financial Report Submissions

Effective immediately, grantees must submit Federal Financial Reports through the Payment Management System rather than the eRA Commons module previously used.

Provide Input on NIH Herpes Simplex Virus Strategic Plan

Share feedback on NIH's Herpes Simplex Virus Strategic Plan and its prioirities for basic research, diagnosis, treatment, cure, and prevention by June 21, 2023.

Bookmark New Resource for Guidance Should You Need to Report a Concern

There are several types of concerns a researcher might need to report to NIH during the application process or while conducting NIH-supported research, from grant scams to research misconduct to peer-review integrity violations.

Citing Publications in Research Performance Progress Reports

Be careful not to over-cite publications, such as preprints, as well as training- and resource-type awards. If an award’s only contribution to a publication is non-personnel resources, do not list the paper.

Minimum Performance Standards, Tax Deductions for Small Business Awardees

Federal income/excess profits taxes are strictly not allowable charges to NIH awards, either as direct or facilities and administrative costs. However, the small business fee may be used to pay for a tax liability.

Inform NIH’s Strategy to Enhance Public Access to Research Results

NIH drafted a Public Access Plan that would alter the NIH Public Access Policy to reflect new priorities identified in a White House Office of Science and Technology Policy memorandum.

Prepare Your First Data Management and Sharing Plan

Start with NIH’s extensive guidance; a new page features sample data management and sharing plans and the frequently asked questions page explains how to account for data management and sharing in your budget.

NIH Shares Data on Investigators with Disabilities

To ensure a strong and diverse workforce and better understand workforce composition and participation in NIH programs, NIH regularly assesses the sex/gender, race, ethnicity,and disability status of its supported researchers.

Non-Discrimination Requirements in All New Grant Opportunities and Awards

HHS offers guidance on how to administer your program in compliance with applicable Civil Rights laws, e.g., sex discrimination and harassment, disability, and religious freedom.

Subscribe to NIH’s All About Grants Podcasts

In each 10- to 20-minute episode, podcast hosts in NIH's Office of Extramural Research discuss the ins and outs of research funding with NIH staff experts.

Provide Input on Clinical Research Infrastructure and Emergency Clinical Trials

Recognizing lessons learned during the COVID-19 pandemic, a new request for information solicits feedback on how to strengthen the capacity of clinical trial infrastructure and emergency trials.

Get the Latest News on NIAID’s New Data Science Website

The refreshed website will help foster a transdisciplinary community of biomedical, clinical, behavioral, and computational scientists working to accelerate research in NIAID's mission areas.

Don’t Forget—Vertebrate Animal Reports Are Due December 1

Your organization's annual vertebrate animal report should cover the 2022 fiscal year, and your institutional official must send the signed report by December 1, 2022.

Join NIAID Staff for Workshop on Genital Herpes

A virtual workshop will define the U.S. and global burden and epidemiology of herpes simplex virus, and then identify gaps and research opportunities in vaccines, therapeutics, prevention, and diagnostics development.

Don’t Take Out Your Frustrations on NIH Staff

Dr. Michael Lauer, NIH’s Deputy Director for Extramural Research, shared example cases of extramural researchers who intimidated, bullied, or made verbal threats directed at NIH staff.

Pandemic Exception Ends for Semiannual Inspection of Animal Facilities

Begining October 1, 2022, all Assured institutions, including those with expiring waivers, must conduct semiannual animal facility inspections as scheduled and required by Public Health Service policy.

How NIH Plans to Share American Indian and Alaska Native COVID Data

Learn how NIH, based on Tribal Consultation feedback, plans to share American Indian and Alaska Native clinical data through the National COVID Cohort Collaborative platform.

Register Now for NIH Training on Data Management and Sharing Policy

Beginning January 25, 2023, NIH will require grant applicants to submit a data management and sharing plan outlining how scientific data and any accompanying metadata will be managed and shared.

Pending Support Includes Submitted Applications Not Yet Reviewed

NIH has policies in place that require disclosure of scientific overlap in separate applications, including those pending support, as demonstrated in a recent peer review integrity case study.

Comment on Protecting Privacy When Sharing Research Participant Data

Provide feedback on how researchers should consider whether to control access to scientific data from participants, even if de-identified and lacking explicit limitations on subsequent use.

Summary of NIH Legislative Mandates for Fiscal Year 2022

Learn about current requirements outlined by statutory provisions to restrict certain uses of funds from NIH grant, cooperative agreement, and contract awards for fiscal year 2022.  

TB Portals Is a Clearinghouse for Tuberculosis Research Data

Explore NIAID’s digital ecosystem to collate clinical, bacterial genomic, and medical imaging data from tuberculosis patient cases to facilitate data exploration and analysis.

Grant Administrators—Note a Helpful Change to Financial Reporting

HHS's Payment Management System will pre-populate the cash transaction section using real-time cash expenses and adjust recipient-reported disbursements to equal cash advance drawdowns on all non-closed subaccounts.

Attend Webinar on Peer Review of Small Business Research Applications

Join us for a webinar on April 19, 2022, to discuss the review process for small business innovation research and small business technology transfer grant applications.

Threshold Change for Special Council Review

The policy requires NIH institute and center Advisory Councils to provide additional consideration for new and renewal applications from already well-supported principal investigators.

Another Chance for Collaboration With ACTG on HIV Remission and Cure

The AIDS Clinical Trials Group (ACTG), an NIAID-supported network, seeks proposals for small clinical trials that can help identify new strategies to address HIV remission and cure.

Updated Budget Guidance for Investigator-Initiated Small Business Grants

The Small Business Administration raised its hard cap (total cost) limits for Phase I and II Small Business Innovation Research and Small Business Technology Transfer grant awards.

Know When To Submit a Public Health Surveillance Request

Eligible awardees may submit a justification as to why their NIH-funded activities should be considered public health surveillance activities, and thus not subject to certain requirements of the revised Common Rule.

Provide Feedback To Inform HHS Five-Year Strategic Plan

Your feedback will help HHS refine and strengthen the objectives and strategies it will pursue to accomplish five strategic goals.

Spots Remain for Webinar on Building Research Infrastructure Capacity

An engaging and informative virtual event will delve into the challenges of capacity building and the opportunities NIH offers to enhance institutional and research infrastructure.

Reminder—Annual Vertebrate Animal Reports Are Due December 1

Your next annual vertebrate animal report should cover the 2021 fiscal year—October 1, 2020, to September 30, 2021—and your institutional official must email the signed report as a PDF by December 1, 2021.

Exclude Pandemic Contingency Plans in Applications

NIH instructed peer reviewers to “assume that temporary, emergency problems arising from the COVID-19 pandemic will be resolved” and not let possible complications affect overall impact scores.

Flexibilities for Animal Facility Inspections

Assured institutions may take advantage of certain flexibilities to reduce administrative burden when conducting semiannual animal facility inspections.

Attend Public Workshop on Bacteriophage Therapy

Register now for the three-day Science and Regulation of Bacteriophage Therapy virtual workshop, at which speakers from government, academia, and industry will discuss regulatory and scientific issues associated with bacteriophage therapy.

NIH Takes Action To End Sexual Harassment in Biomedical Research

NIH expects grant recipients who request changes to the principal investigator, key personnel, or recipient institution to include notification when the requested changes are related to concerns about safety or issues related to sexual harassment, bullying, and other hostile working conditions.

June ACD Meeting Highlights Budget, COVID-19 Response, and UNITE Initiative

NIH's Advisory Committee to the Director (ACD) provides recommendations for program development, resource allocation, NIH administrative regulation and policy, and other specific or general aspects of NIH policy.

Flatten Your PDF Files for the eRA Commons

Learn how to flatten your Portable Document Format (PDF) file attachments before you upload them to the eRA Commons. If you upload a PDF that isn’t flat, it may trigger an eRA Commons error message.

Provide Feedback To Reduce Administrative Burden on Zebrafish Larvae Research

NIH’s Office of Laboratory Animal Welfare seeks input on how to reduce administrative burden while continuing to apply the PHS Policy on Humane Care and Use of Laboratory Animals to zebrafish immediately after hatching.

Reference NIAID’s Revised Strategic Plan for COVID-19 Research

To reflect new evidence and emerging scientific knowledge gaps during the first year of the COVID-19 pandemic, NIAID updated the NIAID Strategic Plan for COVID-19 Research to inform investigators and the public on key scientific areas of interest.

Vertebrate Animals Section—Online Training and Resources

Applicants and offerors, take advantage of NIH’s updated training and other guidance on how to prepare your Vertebrate Animals Section.

Provide Input on Developing 3D Cellular Senescence Maps in Mice

NIH is collecting community feedback on developing 3D cellular senescence maps in mice to inform the role of cellular senescence in health and disease and the consequences of interventions targeting this process.

ACD Meeting Previews NIH Plans To Enhance Diversity and End Structural Racism

NIH is preparing new approaches to longstanding challenges to the biomedical research enterprise, introducing measures to address health disparities, research inclusion, and workforce diversity.

Recent Winter Storms Prompt NIH Natural Disaster Policy

If your institution was closed due to recent winter storms, explain the submission delay in your cover letter and NIH will consider accepting it late.

NIAID Small Business Success Stories From 2020

Check out how 10 companies advanced their innovative technologies with NIAID small business award funds, then learn how to share your own success story.

Plan Ahead for October Meeting on Pulmonary Chemical Injuries

The meeting will focus on topics like emerging science in pathology, pharmacology, and therapeutics for acute lung injury, acute respiratory distress syndrome, interstitial lung disease, and pulmonary fibrosis.

Reference NIH Data on Cumulative Investigator Rates

The Cumulative Investigator Rate is calculated as the number of unique principal investigators (PIs) who were designated on an NIH research project grant divided by the number of unique PIs who were designated on applications over a 5-year period.

Don’t Miss Public Comment Period on Research Involving Children as Subjects

FDA and HHS’s Office for Human Research Protections published Draft Guidance to help stakeholders understand the processes used for review of research involving children as subjects that is not otherwise approvable by an IRB.

Yearly Tallies of the Postdoc Population—Data from NIH

NIH supports many postdocs and graduate students through the Ruth L. Kirschstein National Research Service Award Program, which includes fellowship (“F”) and training (“T”) awards.

Federal Financial Reports Are Serious Business

Grantees must complete a Federal Financial Report either annually or at the end of an award’s project period, as determined by whether the grant is under the streamlined noncompeting award process.

NIAID Expires Recently Issued HIV Cure Interventions NOSI

NIAID expired Notice of Special Interest (NOSI): Opportunities for HIV Cure Interventions at the Time of ART Initiation.

NIH Continues Exploration of Application Trends Amid the Pandemic

Examine the number of R01-equivalent applications submitted by early-stage investigators over corresponding six-month periods, sorted demographically into gender and underrepresented minority groups.

June 2022 ACD Meeting—ARPA-H, COVID-19, UNITE, and Data Sharing

NIH’s Advisory Committee to the Director (ACD) provides recommendations on program development, resource allocation, NIH administrative regulation, and other aspects of NIH policy.

Listen to Podcast Discussion on R56-Bridge Awards

An NIH program officer may nominate your R01 application for R56-Bridge award consideration based on the innovation, merit, and programmatic importance of your proposed research.

Attend Virtual Workshop on Novel Antibacterial and Antifungal Drugs

In June, NIAID is hosting a two-day product development virtual workshop to assist academic groups and small start-ups in all stages of antimicrobial product development.

Nominate an Early-Stage Investigator for SGM Research Award Program

Nominees should be early-stage investigators who have made substantial, outstanding research contributions in areas related to sexual and gender minority health and are poised to become future leaders in the field.

NIH Extends Applicant Guidance During the COVID-19 Pandemic

NIH published a pair of notices extending policy exceptions meant to help investigators continue research and alleviate application hardships during the pandemic.

Provide Input on Search Capabilities Across the Biomedical Landscape

NIH invites feedback from the perspective of data generators, users, and technology providers about researchers’ experiences finding data and expectations for search capabilities.

For Your Consideration—A Trio of Requests for Information

NIH published three requests for information early last month, covering access to NIH data repositories, research on transporters of nutrients, and consent language for future use of data and biospecimens.

Consider an Opportunity From the ACTG Network

Consider applying if you’re able to propose experimental science clinical trials addressing questions important to the AIDS Clinical Trials Group's HIV cure agenda, like quantifying and characterizing HIV reservoirs.

Plan To Attend NIH’s Virtual Regional Seminar in November

NIH will hold its next virtual Regional Seminar on Program Funding and Grants Administration from November 1 to 4, 2021.

Join Small Business Webinar on May 25 for Phase I and II Application Guidance

Participants will learn how to develop successful Phase I and II proposals as well as Phase II Commercialization Plans. Speakers will also discuss how to smoothly manage the award process and post-award expectations.

Name Adjustments for NIAID’s Standing Review Committees

NIAID’s chartered scientific review committees evaluate applications for institutional and educational training, and career development awards.

Third Webinar in NIAID Data Science Series on May 14

Our expert panel will define the traditional silos that may impede broad data sharing and highlight examples of where breaking those silos facilitated advancement that otherwise could not have been achieved.

Second Webinar in NIAID Data Science Series on April 16

Our expert panel will consider three topics related to ethical, legal, and social implications of big data and frame issues for the immune-mediated and infectious disease research community to consider and address.

Review NIH Data Report on Trainee Outcomes

Dr. Michael Lauer, NIH’s deputy director for extramural research, shared data on how many T32 postdoctoral participants eventually serve as a principal investigator on an R01-equivalent award.

Reminder—Respond to Key Immunologic Events RFI by March 15

Send feedback in response to NIAID's request for information (RFI) on identification of key events in autoimmune diseases.

Creating Safe, Diverse Environments for NIH-Supported Conferences

NIH encourages grantees to enhance diversity of conferences by increasing participation of women, underrepresented individuals from diverse racial and ethnic groups and disadvantaged backgrounds, and individuals with disabilities.

Speak Up on Proposed Revisions to the NIH Public Access Policy

NIH is considering revisions to the Public Access Policy following calls from the White House to enhance public access to the results of federally funded research. NIH’s Office of Science Policy will host a listening session on April 12, 2023.

Help NIH Plan a Prize Competition for DEIA Culture Change

The prize competition will acknowledge and reward transformative interventions developed by institutions to create research environments that promote and value diversity, equity, inclusion, and accessibility (DEIA).

An Outage Alert for Grantees Currently Preparing Progress Reports

A scheduled update could disrupt completion of in-progress Research Performance Progress Report budget forms if not submitted before June 22, 2022.

Explore the NIH-Wide Strategic Plan

NIH’s vision for biomedical research direction, capacity, and stewardship focuses on five cross-cutting themes, including Improving Minority Health and Reducing Health Disparities.

ARPA-H Would Boost Biomedical Breakthroughs

President Biden recently proposed creating the Advanced Research Projects Agency for Health (ARPA-H) as a new science organization within NIH, with a mission to accelerate biomedical innovation and adoption of technologies and approaches.

ECHO Program Issues Diversity NOSI and Scientific Approach RFI

NIH’s Environmental influences on Child Health Outcomes (ECHO) Program released a notice of special interest (NOSI) to increase workforce diversity and a request for information (RFI) to collect feedback on strengthening observational research science.

Register Now for First NIAID Data Science Webinar on February 26

NIAID will conduct a series of ideas and innovation webinars to bring together experts and stakeholders in data science, infectious disease, immunology, and immune-mediated disorders.

Register Now for Two-Day Immunosenescence Workshop in May

NIAID is cohosting an Advances in Aging, Immunity, and Chronic Inflammatory Diseases workshop on May 9 and 10, 2023. The workshop will be hybrid, meaning there are options to attend in person or virtually.

Share Input To Make Access to the Innovation Ecosystem More Inclusive

Provide information to help the National Science and Technology Council improve inclusive and equitable access to federal programs and resources.

Ready, Set, Log in to eRA and NCBI

Starting on September 15, 2021, you must use Login.gov credentials and two-factor authentication to access eRA Commons, ASSIST, and Internet-Assisted Review.

Inform Key Aspects of NIH Sleep Disorders Research Plan

NIH's request for information invites comments on how best to pursue basic and clinical investigations of sleep disorders related to acute COVID-19 caused by SARS-CoV-2 infection and Post-Acute Sequelae of COVID-19.

Update to Funding Opportunity for COVID-19 Personal Protective Equipment

A note for those conducting or planning COVID-19-related vaccine or treatment clinical trials and clinical studies supported by NIAID’s fiscal year 2020 emergency pandemic appropriations.

Advice Corner

Caution—Roles Determine Eligibility and Other Requirements

We cover role-related terms that have caused confusion like co-investigator, collaborator, consultant, other significant contributor, and staff scientist.

International Awards—Part III. Build Collaborations

Collaborators may use different types of agreements to facilitate partnerships, including research collaboration agreements, material transfer agreements, and data transfer agreements.

Having Technical Difficulties? Here’s How to Meet the Submission Deadline

Know how to respond if you get the error message “Data Management and Sharing Costs can only be entered on one of the lines in Section F Other Direct Costs within the same budget period."

Don’t Leave Your Mentorships to Chance—Tips for Inviting Support

In practice, most mentees need a developmental mentoring network that consists of multiple social relationships each fostering career development and personal growth.

International Awards—Part II. Foreign Projects

Foreign applications need to propose talent, resources, populations, or environmental conditions not in the United States, e.g., access to a unique study population.

Before You Get Carried Away Planning a No-Cost Extension

In order to spend unobligated funds from an earlier budget period during a no-cost extension, absent automatic carryover authority, you first need to confirm NIAID’s prior approval of a carryover.

International Awards—Part I. Determining Eligibility

The eligibility of a principal investigator differs from that of an institution. This is important in the context of fellowships and career development awards, where non-citizens may be working at U.S. institutions, or U.S. citizens may be working at international institutions.

Seek NIAID’s Help for an Investigator-Initiated Clinical Trial Application

NIAID strongly encourages consultations to apprise principal investigators of the time, cost, and regulatory obligations that come with seeking and receiving an investigator-initiated clinical trial award.

Remember to Address Rigor and Reproducibility in Your Next Application

NIH expects researchers to use unbiased and well-controlled experimental design, methodology, analysis, interpretation, and reporting of results.

Human Subjects System—Refresher and Advice

Use the Human Subjects System to electronically report, view, and update human subjects enrollment, inclusion, and clinical trial data for your NIH applications and grants.

Name-Dropping Does Not Impress Peer Reviewers

Your application is not improved by identifying scientists who aren't significantly advising or participating in your proposed project, and you may inadvertently create conflicts of interest for peer review.

Research Needs Should Motivate No-Cost Extensions

Within a no-cost extension (NCE), your project’s originally approved scope cannot change. That means you may not use an NCE to pursue a new line of investigation at the twilight of a project period.

Fast Facts About Foreign Components

Each funding opportunity announcement has an Eligibility section that indicates whether foreign institutions, foreign components of U.S. institutions, or foreign components are allowed to apply.

Brush Up on Types of Overlap and Other Support for NIH Grant Funding

Overlap may be scientific, budget, or commitment related. To resolve concerns around overlap, you’ll need to provide Other Support information as part of the Just-in-Time process.

Letters of Support Have a Narrow, Evidentiary Purpose

The letters’ text should demonstrate your significant contributors' commitment and summarize the agreements you have in place to support your proposed research project.

Data Management and Sharing Implementation for Contracts

Contract solicitations likely to generate scientific data will include proposal instructions that direct offerors to submit a Data Management and Sharing Plan to the funding institute as part of the technical proposal.

NRSA Training Directors—Good News About Childcare Support

NIH allows childcare costs for dependent children living in the eligible full-time appointed predoctoral or postdoctoral trainee’s home from birth until the age of 13 or, for children who are disabled, until age 18.

Get Answers on Salary Cap and Training Stipends

NIH recently posted a new Stipend and Salary Questions and Answers section to help clarify common points of confusion. It covers funding levels, salary and fringe benefits, stipend levels by year, rebudgeting, and other topics.

Don’t Let Limited Competitions Limit Your Options

If you find a limited competition of interest but your organization is not invited to apply, devise an investigator-initiated application in the same scientific field and apply through a parent announcement.

Know the Nine Application Types

Have you ever wondered what it means when NIH staff or publications refer to a grant application as “type 2” or “type 5”? The type of application matters for your due dates, submission requirements, and relevant NIH rules.

Know the Key Aspects That Differentiate R25 and T35 Training Grants

Research Education Program (R25) and Short-Term Institutional Research Training (T35) grants both offer five-year awards to supplement established training and education programs with part-time educational opportunities.

Know the Importance of Lab Safety in Biomedical Research

Institutions should possess values and behaviors that emphasize safety in both the laboratory and clinical setting, and those who are working in labs must take safety seriously and take precautions to protect themselves.

Clinical Trial or Not? Know the Answer

If your study qualifies as a clinical trial, you need to apply to an appropriate funding opportunity announcement and complete the PHS Human Subjects and Clinical Trials Information section.

Obtain Prior Approval Before Altering Your Project

You can request some prior approvals using the Prior Approval Module in the eRA Commons. Make your request at least 30 days before you want it to take effect.

Changing Institutions? Know What To Do First

If you plan to change institutions, plan well ahead for your ongoing award's corresponding transfer, not after you have moved to the new institution or just before your project ends.

Policy Update on Instruction in the Responsible Conduct of Research

Trainees and instructors, get a quick overview of recent updates to NIH’s responsible conduct of research policy and new recommendations for your instruction in the 2022 to 2023 academic year.

G11 Sample Applications and Opportunity for Foreign Grant Administrators

Three new high-scoring, successful G11 samples reflect excellent grantsmanship and serve as educational resources for other applicants and award administrators.

Understand NIH Expectations for Conference Safety Plans

The Plan To Promote Safe Environments should detail how conference organizers will ensure a safe and respectful setting for all attendees by providing an environment free from discrimination and harassment.

Note a Restriction for Rebudgeting AIDS-Related Research Funds

Whenever you plan research project changes that would shift your research emphasis from one disease area to another, the action likely indicates a change in scope and you thus need to follow NIAID's prior approval procedures.

Understand Circumstances for Adjustments to Application Budget Requests

Learn the reasons why the approved budget listed in your Notice of Award may differ from what you requested in your application.

How To Report Misconduct Allegations

Do you know what to do if you ever spot potential misconduct such as plagiarism, misuse of NIH funds, harassment, human subjects at risk, or other similar issues at an NIH awardee institution?

Write Your Application With Two Audiences in Mind

Write your application to both impress your assigned reviewers and explain your proposed research clearly and concisely to the remaining study section members.

Contacting a Grants Management Specialist—For What and How?

As an applicant or a funded investigator, there’s a good chance you’ll need guidance on administrative or fiscal issues related to your grant or award. Whom should you call for help?

How To Navigate NIAID’s Budget Cap for Renewal Applications

NIAID caps R01 renewal budgets at 20 percent over the direct costs of the last noncompeting award minus supplements, equipment, alterations and renovations costs, and facilities and administrative costs for all subawards.

Send Applications Early To Avoid Electronic Submission Errors

NIAID cannot correct an error spotted in your application after the receipt deadline on your behalf, even if an overlooked content error would render your application nonresponsive to an initiative's requirements.

Know What Interim Paylines Mean for NIAID Awards

NIAID posted interim fiscal year 2022 paylines for research projects, small grants, exploratory/developmental grants, research enhancement awards, and small business technology transfer and small business innovation research grants.

Two New Sample Applications Showcase Good Grantsmanship

Explore full applications and summary statements from recently awarded Phase I small business innovation research (R43) and cooperative agreement (U01) awards.

For Ancillary Studies, Consider NIH Definitions Carefully

You need to assess whether your proposed research qualifies under NIH’s definition of a clinical trial, NIH’s definition of human subjects research, and HHS’s list of exemptions for human subjects research.

Refresher on Select Agents Research Policy and Federal Law

If your research includes a select agent, describe how and where you will use the agent in your application's Research Strategy section, complete the Select Agent Research attachment, and describe biocontainment resources.

Clearing Up Confusion About NOSIs

While investigators have gotten acquainted with notices of special interest (NOSIs), it hasn’t been without some areas of confusion. We address and clarify a few of them here.

Know Which Pandemic-Related Extensions Are Still in Effect

NIH has helped extramural investigators continue their research and alleviate hardships throughout the COVID-19 pandemic by providing guidance, support, and policies on extensions. It might be helpful now to know which of those policies are still in effect.

Review “Related Notices” of Funding Opportunities for Important Updates

If you overlook the “Related Notices” section of a funding opportunity announcement, you may miss vital changes you are meant to observe, such as updated eligibility criteria or due date information.

Determine Project Start Date and Understand Inexact Timing

You can make an initial assessment of the estimated project start date based on the funding opportunity announcement through which you’re applying, but you shouldn’t assume we will make your award on the earliest possible start date from initial estimates.

CDC/NIH Resource Gives Guidance on Biosafety Best Practices

Biosafety in Microbiological and Biomedical Laboratories is an advisory document recommending best practices for safely conducting work in biomedical and clinical laboratories from a biosafety perspective.

Include Special Populations in Your Human Subjects Research

Investigators, if you are proposing human subjects research, be sure to follow NIH’s inclusion policies on special populations, i.e., women, minorities, and all ages.

Acknowledge NIH Support Appropriately in Research Products

NIH staff use award citations to evaluate the impact of grant funding on scientific progress over time. Citing an award that didn’t actually contribute to a research project is just as problematic as failing to cite an award when you should have.

Peer Review, Advisory Group Membership Has Its Benefits

NIH’s Continuous Submission Policy allows appointed members of review and advisory groups to submit applications at any time to R01, R21, and R34 funding opportunity announcements with standard due dates. 

Your Grant Information Can Be Made Public

If you receive a grant from NIH, be aware that anybody can request to see your application and progress report under the Freedom of Information Act (FOIA). If NIH receives a FOIA request, NIH staff will consult with you and your awardee institution.

How To Distinguish Between Delayed Start and Delayed Onset in Human Subjects Research

When planning an application that includes human subjects research that will not begin immediately, you might see two similar research terms—delayed start and delayed onset—which may cause some confusion.

Your NIH Contacts by Application and Grant Stage

For each stage of the grant application process, well-timed guidance from the appropriate NIH or NIAID expert can help you meet requirements, get advice, and more.

Manual of Operations Template for Foreign Institutions

Foreign institutions, take advantage of our new Template for Foreign Institutions—Manual of Operations for Research Awards to document your roles and processes for sponsored research grants and cooperative agreements.

How a Subaward Can Supplement Your Research Activities

A NIH subaward is a collaborative arrangement between a grantee institution and another organization in support of the grantee’s research project.

Some Applications Have Deadlines for Actions Before the Due Date

A variety of funding opportunity announcements either require NIAID’s prior approval or prompt you to contact a program officer for prior consultation far in advance of your application due date.

Find Your Score and More in the Summary Statement

Your summary statement provides a summary of the study section’s discussion, the recommended budget, and criterion scores from assigned reviewers.

Ask Permission, Not Forgiveness, for a Change in Scope

Before implementing a change in scope, you need to request and receive NIAID’s written prior approval. We highly encourage you to discuss the possibility with the assigned program officer before submitting the request.

Reader Questions

“What is the salary cap for a research project grant or cooperative agreement?”

“Can an SBIR or STTR budget include a consulting fee for an expert who helps prepare the grant application?”

“My withdrawn resubmission application is still listed in the eRA Commons. Can I submit an updated version of the same application?”

“Can I avoid the budget cap for renewal applications by submitting a new application instead?”

“Does the big grants policy apply to all NOFOs and NOSIs?”

“Have NIAID’s extramural research priorities changed since Dr. Fauci’s retirement?”

“I applied for a research grant using the FORMS-G application form set. I am now preparing a resubmission application. Which form set should I use?”

“What is a NOFO? How do NOFOs relate to FOAs and NOSIs?”

“What does basic research mean?”

“Should I be using the FORMS-H application form set now?”

“Can a small business apply for an R01 grant?”

“Are there guidelines for the font I use in my application?”

“In my application, should I explain our lab’s contingency plans for the COVID-19 pandemic?”

“Is the National Science Foundation part of NIH?”

“When is the next application due date for NIAID’s Administration Development Award?”

“Do administrative supplements include facilities and administrative costs?”

“Are there any steps I should take before submitting an investigator-initiated program project (P01) grant application?”

“Can I watch the NIAID Advisory Council meetings on September 12, 2022?”

“If I switch institutions, will I need a new eRA Commons account?”

“What is an investigational new drug?”

“What does the term ‘carryover authority’ mean?”

“Does NIH provide special research funding to biomedical researchers with disabilities?”

“What is the next due date for an investigator-initiated K99/R00 application?”

“Can I begin an investigator-initiated small business application now? It looks like the funding opportunity announcement is expired.”

“In section D.2.c Changes in Other Support of the Research Performance Progress Report, should I list the award for which I am submitting the report?”

“How much is NIH’s annual stipend for a postdoc with a fellowship award?”

“How long is the wait from application submission to summary statement upload?”

“What does the term ‘successor-in-interest’ mean?”

“What is NIH’s model organism sharing policy?”

“What is a normal budget request for an investigator-initiated R01 award?”

“The March 5, 2022 application due date is on a Saturday. When is my application really due?”

“For an NIAID Career Transition Award application, how should I demonstrate plans to transition to a full-time assistant professorship?”

“Can I stream the NIAID Advisory Council meetings on January 31, 2022?”

“Are non-U.S. citizens eligible to be the PI of an NIH Research Enhancement Award?”

“Can NIAID help relay my grant’s research findings to a general audience?”

“Are Filipinos considered an underrepresented minority by NIH as related to diversity supplement funding?”

“Does NIH have an up-to-date guide for the FORMS-G application form set?”

“Are there any parent funding opportunity announcements for cooperative agreements?”

“What is the threshold to report first-tier subawards and executive compensation under FFATA?”

“Do most funding opportunity announcements set limits for facilities and administrative costs?”

“Can I watch the NIAID Advisory Council meetings on September 13, 2021?”

“For an investigator-initiated R01 application, must my project period be five years?”

“Do reviewers scrutinize applications from foreign institutions differently?”

“Can I renew an investigator-initiated R21 grant?”

“When and how will I know if my application hasn’t been selected for funding?”

“Does NIAID fund Phase III research conducted by small business grantees?”

“Might the paylines for fellowship applications increase later this year?”

“Does NIAID offer summer internships?”

“Must a principal investigator be a U.S. citizen to receive a research grant award?”

“Can I see an example of a successful fellowship application?”

“Must I keep the title of the grant unchanged when applying for a renewal?”

“I want to add a SARS-CoV-2 component to my ongoing research. Must I request prior approval to do so?”

“What kinds of projects are suitable for a small research grant?”

“Do subawardees need to submit progress reports to NIAID?”

“If I relocate to another country, can I take my NIH funding with me?”

“I am eligible for continuous submission. What is my next submission deadline for an AIDS-related R01 grant application?”

“Does NIAID set a limit for how much total funding support an investigator can receive across all grant awards?”

“Is there a way to tell if or when an expired notice of funding opportunity is likely to be reissued?”

“What is a prize competition? Is it a type of grant or contract?”

“Can a notice of funding opportunity (NOFO) change its requirements after publication?”

“Is the public health emergency exception to the Common Rule requirement for a single institutional review board for multisite research still in effect?”

“I saw NIAID’s DEIA request for information, but I think I answered one of those already?”

“Does NIAID include not discussed applications in the percentile calculation?”

“What demographic data does NIH collect on researchers via their eRA personal profile?”

“How can I follow the NIAID Advisory Council meetings on January 30, 2023?”

“Can a foreign investigator serve as a peer reviewer?”

“Do due dates differ for new and resubmission applications?”

“What is the budget cap for an investigator-initiated small business grant application?”

“Do stipends or the salary cap make adjustments based on locality?”

“Does the NIH Natural Disaster Policy apply to recent hurricanes Fiona and Ian?”

“Can I embed a video clip in my application’s Research Strategy section?”

“Is there a limit on how many times a research project (R01) grant can be renewed?”

“What is the ‘Research Education Outcomes’ attachment for an R25 application?”

“Is my application anonymized before peer review?”

“What is NIH’s rule for late applications due to inclement weather?”

“Must I be a U.S. citizen to apply for an NIAID Career Transition Award?”

“I know NIAID’s prior approval is needed to reduce an investigator’s level of effort on a grant by 25 percent or more. Would a decrease from 50 percent effort to 30 percent effort need prior approval?”

“Does NIAID use peer review for research and development contract proposals?”

“Is childcare assistance available for researchers working under an NIAID award who do not have an NRSA fellowship award?”

“Why isn’t a single program officer overseeing all my grants?”

“Am I required to apply in English, or can I use another language to write my application?”

“Does NIH consider me an early-stage investigator if I’ve received a U01 award?”

“Is there a webpage that lists all of NIAID’s standard operating procedures for grants?”

“Can I submit a renewal application after my current project period has ended?”

“My planned research project fits well with two initiatives. Can I apply to both?”

“Must I obtain prior approval to reduce effort during a no-cost extension?”

“Does NIAID maintain a list of open contract solicitations?”

“Are there due dates for revision applications or is the deadline continuous?”

“Can an investigator with appointments at two distinct institutions be the PI for an award at one and oversee a subaward (from the same grant) at the other?”

“How does NIH determine my status as an early-stage investigator?”

“Does resolving a bar to award improve my application’s score in peer review?”

“Where should I list references used to justify key aspects of my research plan?”

“Can I submit two renewal applications to pursue two different aspects of a single R01 award?”

“For a resubmission application, if I previously received NIAID’s agreement to accept assignment of a big grant for the new application, can I use the same acceptance letter?”

“Are any funding opportunities tailored to researchers with an M.D.?”

“What is the ‘cap’ for renewal applications?”

“When is my Research Performance Progress Report due?”

“Why does NIH use percentiles for investigator-initiated R01 applications instead of overall impact score?”

“What is an interim research product?”

“Can an institution apply an inflation rate to its budget on competing grant applications?”

“Is CDC part of NIH?”

“What does the acronym BESH stand for?”

“Is a funding opportunity announcement’s expiration date also the deadline to apply?”

“Must I use a particular internet browser when applying for a grant?”

“I am an established principal investigator (PI), and my multiple PI application includes a new PI. Will the application qualify for NIAID’s new investigator payline?”

“In my application’s biosketch, can I cite a manuscript that was submitted to a journal but hasn’t yet been accepted?”

“How can I apply for an R56-Bridge award?”

“Can I spend small business funds on research in a foreign country?”

“What is the minimum level of effort required on a grant?”

“When it comes to applying for NIH grants and scholarships, who qualifies as an underrepresented person?”