Seeking Research Applications To Understand the Natural History of STIs

Funding News Edition: January 09, 2019
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Advance the understanding of the natural history of infection for three sexually transmitted infections (STIs): gonorrhea, syphilis, and chlamydia. NIAID issued a new R01 funding opportunity announcement (FOA) Control of Sexually Transmitted Infections (STIs) Through a Comprehensive Understanding of the Natural History of Infection (R01, Clinical Trial Not Allowed).

Application Focus

In your application, address the natural history of infection in the context of: 1) correlates of protection, 2) host response to infection, 3) clinical endpoints of disease, or 4) biological and clinical factors that influence clearance rather than persistence of infection.

Examples of scientific knowledge we want to support include but are not limited to:

  • Clinical studies to understand the natural history of infection and the burden of sequelae
  • Natural history studies to inform mechanisms of immunity
  • Studies to determine human immune responses to various antigens that could be vaccine or diagnostic candidates
  • Studies of clinical cohorts to use “omics”-type approaches for the study of protective and pathogenic host responses
  • Studies that advance the development of better vaccines, therapeutics, and diagnostics through improved understanding of disease

NIAID will consider applications focusing on HIV/AIDS nonresponsive and withdraw them prior to review.

Administrative Details

NIH’s standard Application Due Dates apply to this FOA. The first due date is February 5, 2019.

Keep in mind your budget is not limited but should reflect the actual needs of your proposed project. Follow our Big Grants policy if you plan to request $500,000 or more in direct costs in any one year.

As for the project period, the maximum allowed is five years; however, the number of years you request should be based on the scope of your project.

Direct your NIAID-related scientific questions to Dr. Leah Vincent.

Contact Us

Email us at deaweb@niaid.nih.gov for help navigating NIAID’s grant and contract policies and procedures.

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