A new set of funding opportunity announcements (FOAs) titled Developmentally Tailored HIV Prevention and Care Research for Adolescents and Young Adults seeks to address significant HIV health disparities in youth by focusing on developmental factors. NIAID is participating in the R01, Clinical Trial Optional and R21, Clinical Trials Not Allowed Guide announcements but not in the related R34, Clinical Trial Optional Guide announcement.
Successful applicants will focus on how developmental factors across adolescence and emerging adulthood
- Influence risk and resilience to HIV
- Influence how youth cope with living with HIV
- Affect the impact of HIV prevention and treatment interventions
NIAID is especially interested in developmental research or interventions that can be incorporated into HIV prevention and treatment interventions or improve their impact. Examples of such projects include advancing the following:
- Interventions that capitalize on youths’ social networks (in person or online) to speed up disseminating new biomedical prevention options or enhance engagement in HIV care for youth living with HIV
- Methods or measures to assess developmental readiness or predict developmental capacity for autonomous adherence to biomedical prevention or treatment
- Differentiated care models for youth to improve outcomes along the HIV care continuum
We also seek studies on methods or interventions to assess readiness for or assist with the transition from pediatric or adolescent HIV care to adult HIV care, as well as research to better understand violence as an obstacle to youths' engaging in and adhering to HIV prevention and treatment.
Read the FOAs linked above for a larger list of possible research topics, including priority mechanisms, relationships, and intervention targets and improvements of interest to HIV prevention and continuum of care.
Given the significant amount of heterogeneity that exists among adolescents and emerging adults, researchers should consider the use of different metrics for measuring development beyond chronological age. Next, your research needs to take into consideration the heterogeneity of youth as well as sex and gender differences.
Finally, given the importance of incorporating youth input throughout the research process, youth advisory boards are required for all submissions to this FOA.
Both the R21 and R01 opportunities follow NIH’s Standard Due Dates.
The maximum project period is two years for the R21 and five years for the R01.
For the R21 your combined budget for direct costs may not exceed $275,000, with no more than $200,000 requested in any single year. For the R01, your budget is not limited but should reflect the actual needs of your proposed project.
Contact Naana Cleland, NIAID’s scientific/research contact for these opportunities, if you have any questions.