News Releases

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December 2014

  • Estrogen Worsens Allergic Reactions in Mice

    December 29, 2014

    Estradio enhances the levels and activity in mice of an enzyme that drives life-threatening allergic reactions, according to researchers from the National Institute of Allergy and Infectious Diseases. 

  • Stem Cell Transplants May Halt Progression of Multiple Sclerosis

    December 29, 2014

    ​Three-year outcomes from an ongoing clinical trial suggest that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis. 

  • Scientists Report on Trial of Early-Generation Ebola, Marburg Vaccine Candidates

    December 23, 2014

    Results of an early-stage clinical trial of two experimental vaccines against Ebola and Marburg viruses-the first to be completed in an African country-showed that they were safe and induced immune responses in healthy volunteers. 

  • Imaging Techniques Reliably Predict Treatment Outcomes for TB Patients

    December 4, 2014

    Two medical imaging techniques, called positron emission tomography and computed tomography, could be used in combination as a biomarker to predict the effectiveness of antibiotic drug regimens being tested to treat tuberculosis patients.

  • NIH-Led Scientists Describe New Herpes Treatment Strategy

    December 3, 2014

    Scientists have developed a novel treatment approach for persistent viral infections such as herpes.

  • NIH Statement on World AIDS Day 2014

    December 1, 2014
    ​Remarkable progress has been made in the fight against HIV/AIDS since the first annual World AIDS Day was commemorated 26 years ago. Yet, we are still far from achieving our goal of a world without AIDS.  

November 2014

October 2014

  • Model by NIH Grantees Explains Why HIV Prevention Dosing Differs by Sex

    October 30, 2014

    A mathematical model developed by NIH grantees predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection via anal sex.

  • NIH-Led Study Explores Prevention of Heart Disease in HIV-Infected People

    October 28, 2014

    ​The National Institutes of Health has launched a clinical trial to assess the effects of aspirin and cholesterol-lowering drugs, or statins, on preventing cardiovascular disease in people with long-term HIV infections. This group, which includes people on antiretroviral therapy (ART) as well as "elite controllers" who can limit the virus without ART, have a higher risk of developing heart disease and stroke compared to the general population. The study is funded by NIH's National Institute of Allergy and Infectious Diseases (NIAID).

  • BULLETIN: In South Africa, RV144 HIV Vaccine Regimen Induces Immune Responses Similar to Those Seen in Thailand

    October 28, 2014

    ​The investigational HIV vaccine regimen that showed a modestly protective effect in the landmark RV144 clinical trial conducted in Thailand was shown to be safe and elicited robust immune responses when tested among 100 healthy adults in South Africa, according to findings presented today at the HIVR4P conference in Cape Town, South Africa. The results from the trial, called HVTN 097, bode well for plans to test a similar experimental vaccine regimen in South Africa beginning in 2015 in an effort to build upon the results of the RV144 study.

  • NIH Begins Early Human Clinical Trial of VSV Ebola Vaccine

    October 22, 2014

    ​Human testing of a second investigational Ebola vaccine candidate is under way at the National Institutes of Health's Clinical Center in Bethesda, Maryland.

  • NIH Grants License Agreement for Candidate Ebola Vaccines

    October 15, 2014

    The National Institute of Allergy and Infectious Diseases today announced a new license agreement aimed at advancing dual-purpose candidate vaccines to protect against rabies and Ebola viruses. 

  • NIH-Supported Scientists Unveil Structure, Dynamics of Key HIV Molecules

    October 8, 2014

    New research has illuminated the movement and complete structure of the spikes on HIV that the virus uses to bind to the cells it infects.

  • Gene Therapy Shows Promise for Severe Combined Immunodeficiency

    October 8, 2014

    Researchers have found that gene therapy using a modified delivery system, or vector, can restore the immune systems of children with X-linked severe combined immunodeficiency (SCID-X1).

  • Candidate H7N9 Avian Flu Vaccine Works Better with Adjuvant

    October 7, 2014

    ​An experimental vaccine to protect people against H7N9 avian influenza prompted immune responses in 59 percent of volunteers who received two injections at the lowest dosage tested but only if the vaccine was mixed with adjuvant. 

September 2014

August 2014

  • NIH to Launch Human Safety Study of Ebola Vaccine Candidate

    August 28, 2014

    ​Initial human testing of an investigational vaccine to prevent Ebola virus disease will begin next week by the National Institute of Allergy and Infectious Disease, part of the National Institutes of Health.

  • HIV Antibodies Block Infection by Reservoir-Derived Virus in Laboratory Study

    August 26, 2014

    A laboratory study led by scientists from the National Institute of Allergy and Infectious Diseases lends further weight to the potential effectiveness of passive immunotherapy to suppress HIV in the absence of drug treatment.

  • NIH Scientists Establish New Monkey Model of Severe MERS-CoV Disease

    August 21, 2014

    NIH scientists have found that Middle East respiratory syndrome coronavirus infection in marmosets closely mimics the severe pneumonia experienced by people infected with MERS-CoV, giving scientists the best animal model for testing potential treatments.

  • Test Reliably Detects Inherited Immune Deficiency in Newborns

    August 20, 2014

    A newborn screening test for severe combined immunodeficiency (SCID) reliably identifies infants with this life-threatening inherited condition, leading to prompt treatment and high survival rates, according to a study supported by the National Institutes of Health. Researchers led by Jennifer Puck, M.D., of the University of California, San Francisco, also found that SCID affects approximately 1 in 58,000 newborns, indicating that the disorder is less rare than previously thought.

  • Experimental Chikungunya Vaccine Induces Robust Antibody Response

    August 14, 2014

    An experimental vaccine to prevent the mosquito-borne viral illness chikungunya elicited neutralizing antibodies in volunteers who participated in an early-stage clinical trial conducted by researchers at the National Institute of Allergy and Infectious Diseases.

  • Ebola Outbreak Highlights Global Disparities in Healthcare Resources

    August 13, 2014

    The outbreak of Ebola virus disease that has claimed more than 1,000 lives in West Africa this year poses a serious, ongoing threat to that region: the spread to capital cities and Nigeria..

  • NIH-Led Scientists Boost Potential of Passive Immunization Against HIV

    August 13, 2014

    Scientists are pursuing injections or intravenous infusions of broadly neutralizing HIV antibodies (bNAbs) as a strategy for preventing HIV infection.

  • NIH and Italian Scientists Develop Nasal Test for Human Prion Disease

    August 6, 2014

    A nasal brush test can rapidly and accurately diagnose Creutzfeldt-Jakob disease, an incurable and ultimately fatal neurodegenerative disorder, according to a study by National Institutes of Health scientists and their Italian colleagues.

July 2014

June 2014

May 2014

April 2014

  • NIH Scientists Establish Monkey Model of Hantavirus Disease

    April 28, 2014
    WHAT:

    National Institutes of Health (NIH) researchers have developed an animal model of human hantavirus pulmonary syndrome (HPS) in rhesus macaques, an advance that may lead to treatments, vaccines and improved methods of diagnosing the disease. The study, conducted by researchers at NIH's National Institute of Allergy and Infectious Diseases (NIAID), is published in the Proceedings of the National Academy of Sciences.

  • Study Sheds Light on How the Immune System Protects Children from Malaria

    April 17, 2014

    Children who live in regions of the world where malaria is common can mount an immune response to infection with malaria parasites that may enable them to avoid repeated bouts of high fever and illness and partially control the growth of malaria parasites in their bloodstream.

  • NIH Funds Influenza Research and Surveillance Network

    April 9, 2014

    ​Influenza scientists at five sites in the United States are to receive funding from the National Institute of Allergy and Infectious Diseases to collaborate with investigators around the globe in a network designed to advance understanding of influenza viruses and how they cause disease.

  • Genetic Defect May Confer Resistance to Certain Viral Infections

    April 9, 2014

    A National Institutes of Health study reports that a rare genetic disease, while depleting patients of infection-fighting antibodies, may actually protect them from certain severe or recurrent viral infections.

  • NIH Funding Opportunity Focuses on Diagnostics for Hospital-Based Antibacterial-Resistant Infections

    April 7, 2014

    ​The National Institute of Allergy and Infectious Diseases announced a research funding opportunity to develop and/or produce diagnostics to quickly detect the key bacteria responsible for antibacterial-resistant infections in hospital settings. 

  • Future HIV Vaccine Research Must Consider Both Protective Immune Responses and Those that Might Increase Susceptibility to Infection

    April 3, 2014

    The National Institute of Allergy and Infectious Diseases held a scientific meeting to examine why certain investigational HIV vaccines may have increased susceptibility to HIV infection. 

March 2014

  • HIV-Infected Men at Increased Risk for Heart Disease, Large Study Finds

    March 31, 2014

    The buildup of soft plaque in arteries that nourish the heart is more common and extensive in HIV-infected men than HIV-uninfected men, independent of established cardiovascular disease risk factors, according to a new study by National Institutes of Health grantees.

  • World TB Day 2014

    March 24, 2014

    The number of individuals falling ill or dying from tuberculosis (TB) worldwide has slowly been declining. However, the global burden of this ancient disease is still substantial.

  • Fauci: Robust Research Efforts Needed to Address Ongoing, Global Challenge of Antimicrobial Resistance

    March 20, 2014

    Given the evolutionary ability of microbes to rapidly adapt, the threat of antimicrobial resistance likely will never be eliminated. This crisis must be addressed with a multi-faceted approach that includes a strong base of basic, clinical and translational research.

  • Scientists Describe Gut Bacteria that Cause Sepsis in Preterm Infants

    March 19, 2014

    Researchers studying intestinal bacteria in newborns have characterized the gut bacteria of premature infants who go on to develop sepsis, a serious and potentially life-threatening condition caused by bacteria in the bloodstream. 

  • NIH Grantees Sharpen Understanding of Antibodies that May Cut Risk of HIV Infection

    March 19, 2014

    Two studies bring scientists identify previously unrecognized attributes of antibodies that appear to have reduced the risk of HIV infection in the only clinical trial to show efficacy, albeit modest, of an experimental vaccine regimen in people.

  • NIH Scientists Track Evolution of a Superbug

    March 17, 2014

    Using genome sequencing, National Institutes of Health scientists and their colleagues have tracked the evolution of the antibiotic-resistant bacterium Klebsiella pneumoniae sequence type 258 (ST258), an important agent of hospital-acquired infections.

  • Genetic Modification of Cells Proves Generally Safe as HIV Treatment Strategy

    March 5, 2014

    Scientists report initial results from humans on the safety and tolerability of a novel strategy to curb HIV disease by removing key cells from HIV-infected individuals, genetically modifying the cells to resist HIV infection and returning them to those individuals. 

  • NIH Seeks Input on HIV Cure Research Priorities

    March 3, 2014

    The National Institutes of Health is asking the scientific community to weigh in on the highest priority research areas related to understanding HIV persistence and investigating strategies for eradicating or controlling remaining virus despite optimal antiretroviral treatment.

  • Study of Antibody Evolution Charts Course toward HIV Vaccine

    March 3, 2014

    A scientific team has discovered how the immune system makes a powerful antibody that blocks HIV infection of cells by targeting a site on the virus called V1V2.

  • International Scientists Convene to Chart Path, Measure Progress Toward Global Vaccine Research and Development

    March 3, 2014

    Leading scientists, vaccine developers and public health officials gaithered in March 2014, at the Global Vaccine and Immunization Research Forum to set priorities and assess progress in research and development for vaccines to prevent diseases that threaten public health worldwide. 

  • NIH Team Identifies New Genetic Syndrome

    March 3, 2014

    Researchers have identified a new genetic syndrome characterized by a constellation of health problems, including severe allergy, immune deficiency, autoimmunity and motor and neurocognitive impairment. 

February 2014

January 2014