Autoimmune Diseases News Releases

Epstein-Barr Virus Protein Can “Switch On” Risk Genes for Autoimmune Diseases
April 16, 2018

Infection with Epstein-Barr virus (EBV), the cause of infectious mononucleosis, has been associated with subsequent development of systemic lupus erythematosus and other chronic autoimmune illnesses, but the mechanisms behind this association have been unclear. Now, a novel computational method shows that a viral protein found in EBV-infected human cells may activate genes associated with increased risk for autoimmunity. Scientists supported by the National Institute of Allergy and Infectious Diseases report their findings today in Nature Genetics.

Islet Transplantation Improves Quality of Life for People with Hard-to-Control Type 1 Diabetes
March 21, 2018

Quality of life for people with type 1 diabetes who had frequent severe hypoglycemia—a potentially fatal low blood glucose (blood sugar) level—improved consistently and dramatically following transplantation of insulin-producing pancreatic islets, according to findings published online March 21 in Diabetes Care.

Stem Cell Transplant for Severe Scleroderma Improves Survival, Quality of Life
January 3, 2018

New clinical trial findings show that a therapeutic regimen involving transplantation of a person’s own blood-forming stem cells can improve survival and quality of life for people with severe scleroderma, a life-threatening autoimmune disease. The regimen, known as myeloablative autologous hematopoietic stem cell transplant (HSCT), includes chemotherapy and total body radiation to destroy the bone marrow followed by transplantation of the person’s own blood-forming stem cells to reconstitute the marrow and immune system.

Stem Cell Transplants May Induce Long-Term Remission of Multiple Sclerosis
February 1, 2017

New clinical trial results provide evidence that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells can induce sustained remission of relapsing-remitting multiple sclerosis (MS), an autoimmune disease in which the immune system attacks the central nervous system. 

Islet Transplantation Restores Blood Sugar Awareness and Control in Type 1 Diabetes
April 18, 2016

New clinical trial results show that transplantation of pancreatic islets—cell clusters that contain insulin-producing cells—prevents severe, potentially life-threatening drops in blood sugar in people with type 1 diabetes.

Stem Cell Transplants May Halt Progression of Multiple Sclerosis
December 29, 2014

​Three-year outcomes from an ongoing clinical trial suggest that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis.