Scientists have generally believed that HIV and its monkey equivalent, SIV, gain a permanent foothold in the body very early after infection, making it difficult to completely eliminate the virus even after antiretroviral therapy has controlled it. Now NIH-supported researchers report that SIV can become entrenched in tissues fewer than 3 days after infection, before the virus is detectable in blood plasma (the liquid part) or blood cells.
Whitney et al. Rapid seeding of the viral reservoir prior to SIV viremia in rhesus monkeys. Nature DOI: 10.1038/nature13594 (2014).
Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, is available for comment.
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