According to a study published today in PLOS Pathogens, children who live in regions of the world where malaria is common can mount an immune response to infection with malaria parasites that may enable them to avoid repeated bouts of high fever and illness and partially control the growth of malaria parasites in their bloodstream. The findings may help researchers develop future interventions that prevent or mitigate the disease caused by the malaria parasite.
S Portugal et al. Exposure-dependent control of malaria-induced inflammation in children. PLOS Pathogens DOI: 10.1371/journal.ppat.1004079 (2014).
Peter D. Crompton, M.D., M.P.H., chief, Malaria Infection Biology and Immunity Unit in the Laboratory of Immunogenetics, part of NIAID's Division of Intramural Research.
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