Microbicides To Prevent HIV Transmission In Vivo

This service provides evaluation of products in animal efficacy models. A product must demonstrate a potent and selective activity profile in the in vitro microbicide screening algorithm prior to its acceptance as a candidate for this service. Studies to determine optimal routes and schedules of drug administration can be performed.

Non-human Primate Model

  • Macaques are inoculated with SIV or SHIV.
  • Antiviral efficacy can be demonstrated via changes in virologic and immunologic parameters.

The current contractor for this service is Advanced BioScience Laboratories, Kensington, Maryland.​

Content last reviewed on July 7, 2009