Research in the Molecular Genetics Section focuses on the identifying components and determining mechanisms involved in transcription of herpes simplex virus (HSV) genes during the initiation of lytic infection and during viral reactivation from latency. This includes the integration of transcription factors, coactivators, epigenetic machinery, and transcription elongation factors that impact the expression of the first wave of viral genes.
In some instances, understanding the roles of these components can lead to translational studies that explore the potential of targeting essential/critical components as an approach to suppress HSV infection and disease.
Jesse H. Arbuckle, Ph.D.
Senior Research Assistant
Education:
Ph.D., Biomedical Sciences/Virology, 2011, University of South Florida College of Medicine
Dr. Jesse Arbuckle received his Ph.D. for his work on the chromosome integration of Human Herpesvirus-6A and 6B during latency. In the Molecular Genetics Section Dr. Arbuckle has examined the chromatin remodeler CHD3 and the histone methyltransferase EZH2 function in herpes simplex virus lytic gene expression. His research interests include using in vivo mouse models to understand the chromatin...
Jodi L. Vogel, Ph.D.
Staff Scientist
Education:
Ph.D., Biochemistry, 1989, The University of Alabama at Birmingham
Dr. Jodi Vogel received her Ph.D. for her work on functions of the bacteriophage Mu repressor protein. She then moved to the Laboratory of Susan Lindquist at the University of Chicago where she elucidated the role of heat shock proteins in the regulation of mRNA splicing in a yeast model system. Dr. Vogel joined the Molecular Genetics Section in 1994 where she has focused on characterization of...
Former Research Group Members
Hua Peng, Ph.D.
Principal Investigator, Key Laboratory of Infection and Immunity, Chinese Academy of Sciences
Bharat Khurana, Ph.D.
Director, Regulatory Strategies, Takeda
Aarthi Narayanan, Ph.D.
Associate Professor, George Mason University
Director of Research, American Type Culture Collection
Mauricio Nogueira, Ph.D.
Professor, Faculdade de Medicina de Sao Jose do Rio Preto
International Faculty, University of Texas Medical Branch
Yu Liang, Ph.D.
Director II, WuXi Biologics-Discovery
Ann-Marie Turner, Ph.D.
Assistant Professor, University of North Carolina at Chapel Hill
Roberto Alfonso-Dunn, Ph.D.
Research Scientist, TISCH MS Research Center of New York
Gaelle Kolb, Ph.D.
Proposal Manager, Office of the Vice President for Research-University of Maryland
Zackary Whitlow, Ph.D.
Principal Control Engineer, Helmerich and Payne
Andy Yanez, B.S.
M.S. Student-University of Texas School of Public Health