Resources for Researchers
The ACTG NL consists of Core Laboratory groups in immunology, pharmacology, virology and TB.
The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.
The ARLG biorepositories were created to aid in the development and evaluation of novel diagnostic tests and laboratory techniques, study mechanisms of resistance, generate preliminary data for study concepts, and support/mentor early-stage investigators pursuing research in the field of antibact
The Consortium for TB Biomarkers (CTB2) has created a collaborative biobank in order to accelerate the development of new drugs and treatments for tuberculosis by validating and exploring biomarkers of response to TB drug treatments. The biobank will ultimately house biospecimens from 1000 adult
The RSC Public Website, run by the DAIDS Regulatory Support Center (RSC) contractor, has been used in the DAIDS community for over 10 years and is a primary platform to communicate updates to templates, process changes, and other information needed by the RSC research community.
Repository of specimens collected as part of the DAIDS VAX004 Clinical Trial.
The STAT3base contains a listing of STAT3 mutations in human HIES identified in the Laboratory of Clinical Immunology and Microbiology as well as those published in the literature.
This service can be used to develop and perform a variety of analytical assays to assess the properties of drug substances and their formulations.
This service program supports the development and manufacture, of a wide variety of pharmaceutical dosage formulations, including tablets, capsules, semi-solid preparations, injectibles, and sustained-release products. If requested, manufacturing can be done under GMP.
The HVTN shares data and specimens collected in its studies with investigators who would like to use our materials to answer research questions related to vaccinology, immunology, or HIV/AIDS.
HVTN provides structured mentorship and project funding to investigators working on HIV vaccines.
This service provides chemical synthesis of lead compounds for use in additional drug development studies. Compounds must previously have been successfully synthesized to be candidates for this service. Synthesis of new analogs is not supported.
The HIV Prevention Trials Network (HPTN) offers two scholarship programs for early-career investigators funded through a supplement from the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute on Drug Abuse (NIDA).
The Immcantation framework is developed as a start-to-finish analytical ecosystem for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires from high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.
ImmPort is a Web portal that contains data from NIAID-funded immunology studies, including basic research and clinical trials. The portal provides online tools that allow users to analyze the data and visualize the results.
The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Early Career Investigator Mentored Research program aims to support the development of early career investigators to enter the field of maternal/child HIV research and advance the mission of the IMPAACT Network.
The main purpose of the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center is to support the network’s scientific agenda by providing state of the art laboratory testing in support of clinical trials, new works concept sheets (NWCS), and data analysis con
The ICSSC provides a wide range of support services to clinical investigators who are conducting international research funded by the Division of Microbiology and Infectious Diseases (DMID), including consultation and assistance to investigators for protocol development, site assessment, data man
A common data model for sharing observational HIV data has been developed by the International epidemiology Databases to Evaluate AIDS (IeDEA). The IeDEA DES is used by the seven operational regions of IeDEA to exchange data with each other for collaborative research studies.
The Microbicide Trials Network (MTN) is a NIAID-funded worldwide collaborative clinical trials network focused on preventing the sexual transmission of HIV. The MTN accepts concepts for new protocols, ancillary study proposals, secondary data analysis requests, and dataset requests.
The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles.
The MACS collects and stores a variety of biological specimens. Inventory may be housed at the national level or a subset at the local level. The MACS Center for the Coordination and Analysis of MACS (CAMACS) coordinates and facilitates completion of specimen requests.
Researchers involved with the NIAID Clinical Genomics Program study many diseases of the immune system that are rare and not well understood but often shed light on basic immune function and more common immune disorders.
The National Institutes of Health (NIH) AIDS Reagent Program provides critical research reagents and resources to the scientific community. The ARP acquires, develops, and produces state-of-the-art reagents and provides these reagents at no cost to qualified investigators throughout the world.
The Phase I Clinical Trial Units for Therapeutics support the design, development, implementation, and conduct of Phase I clinical trials to assess safety, pharmacokinetics, and/or pharmacodynamics of licensed and investigational therapeutic products, including immunomodulatory agents and monoclo