Filter Search Results

Resources for Researchers

NIAID offers many resources to support your research, including reagents, model organisms, and tissue samples, to name just a few. Use the filters under Filter Search Results to narrow your search, or simply enter specific search terms in the search field.

Showing results filtered by:
ClEAR ALL
Preclinical
28 Results

Center for International Blood and Marrow Transplantation Research (CIBMTR) Database

The CIBMTR database contains data on outcomes of hematopoietic (blood and bone marrow) cell transplant (HCT) procedures.

ChemDB HIV, Opportunistic Infection and Tuberculosis Therapeutics Database (ChemDB)

The ChemDB database contains information extracted from scientific literature on the structure and activity of compounds that have been tested against HIV, opportunistic pathogens and TB.

Comprehensive Resources for HIV Microbicides and Biomedical Prevention (CRMP)

This contract provides gap-filling support services for HIV prevention drug developers including academic (investigators), for-profit and not-for-profit small and large companies, and other product innovators (henceforth identified as Sponsors) for the development of HIV non-vaccine biomedical pr

DAIDS Regulatory Support Center (RSC)

The RSC Public Website, run by the DAIDS Regulatory Support Center (RSC) contractor, has been used in the DAIDS community for over 10 years and is a primary platform to communicate updates to templates, process changes, and other information needed by the RSC research community.

DAIDS VAX004 Clinical Trial Specimens

Repository of specimens collected as part of the DAIDS VAX004 Clinical Trial.

Heterogeneity in Human Immune Cells

Heterogeneity in Human Immune Cells is a website providing interactive figures (iFigs) for a recent study of protein expression heterogeneity in human immune cells conducted by Dr.

HIV Database and Analysis Unit

The HIV Database & Analysis Unit provides an integrated repository of HIV sequence and immunology published data, by curating & maintaining a relational database with searchable web access for the scientific community; and (ii) develop web-based computation analysis methods and tools for

HIV Drug Development: Analytical Chemistry Services

This service can be used to develop and perform a variety of analytical assays to assess the properties of drug substances and their formulations.

HIV Drug Development: In Vitro Efficacy Evaluations

This service provides follow-up studies of products which already have been evaluated in a biochemical or cell-based assay and shown to possess an activity profile that warrants further development of the product as an HIV therapeutic.

HIV Drug Development: In Vivo Efficacy Evaluations

This service provides evaluation of products in animal efficacy models. A product must demonstrate a potent and selective activity profile in vitro against the HIV strain used in the model prior to its acceptance as a candidate for this service.

HIV Drug Development: Preclinical Pharmacology and Toxicology Services

This service can be used to provide pharmacokinetic and safety assessments of products in mice, rats, rabbits, dogs, and nonhuman primates.

HIV Drug Formulation Development and Manufacturing Services

This service program supports the development and manufacture, of a wide variety of pharmaceutical dosage formulations, including tablets, capsules, semi-solid preparations, injectibles, and sustained-release products. If requested, manufacturing can be done under GMP.

HIV Vaccine Trials Network (HVTN): Ancillary/Exploratory Studies

The HVTN shares data and specimens collected in its studies with investigators who would like to use our materials to answer research questions related to vaccinology, immunology, or HIV/AIDS.

HIV Vaccine Trials Network (HVTN): Scholar Awards

HVTN provides structured mentorship and project funding to investigators working on HIV vaccines.

HIV/TB Drug Development: Chemical Synthesis

This service provides chemical synthesis of lead compounds for use in additional drug development studies. Compounds must previously have been successfully synthesized to be candidates for this service. Synthesis of new analogs is not supported.

Immcantation Portal

The Immcantation framework is developed as a start-to-finish analytical ecosystem for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires from high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.

In Vitro Assessment for Antimicrobial Activity Program

The In Vitro Assessment for Antimicrobial Activity program provides capability in a broad range of in vitro assessments to evaluate promising candidate countermeasures for antimicrobial activity against microbial pathogens and vectors, including those derived from clinical speci

Microbicides to Prevent HIV Transmission In Vitro

This service provides evaluation of products that have already been evaluated in a biochemical or cell-based assay and shown to possess an activity profile that warrants further development as a microbicide.

Multicenter AIDS Cohort Study (MACS) Public Data Set

The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles.

NIAID Clinical Genomics Program Resources

Researchers involved with the NIAID Clinical Genomics Program study many diseases of the immune system that are rare and not well understood but often shed light on basic immune function and more common immune disorders.

NIH AIDS Reagent Program

The National Institutes of Health (NIH) AIDS Reagent Program provides critical research reagents and resources to the scientific community. The ARP acquires, develops, and produces state-of-the-art reagents and provides these reagents at no cost to qualified investigators throughout the world.

Preclinical Development Support Master Contract (PDSMC)

The Preclinical Development Support Master Contract (PDSMC) supports all phases of preclinical development, including process and product development, GMP manufacturing and clinical lot production, analytical and formulation, preclinical enabling studies and associated tasks leading to the filing

Preclinical Models of Infectious Disease

Preclinical models support animal models and animal replacement technologies development and refinement as well as testing services, ranging from screening and proof-of-concept to GLP efficacy studies.

    Process Development and Analytical Support Contract (PAS)

    The Process Development and Analytical Support Contract (PAS) supports two key critical components: process development and analytical characterization activities. 

    This contract is with the International Aids Vaccine Initiative (IAVI).

    QuSAGE: Quantitative Set Analysis for Gene Expression

    This Gene Set Enrichment-type test designed for analysis of microarray and RNASeq data is designed to provide a faster, more accurate, and easier to understand test for gene expression studies. QuSAGE extends previous methods with a complete probability density function (PDF).