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The aerobiology section at the Integrated Research Facility at Fort Detrick (IRF‑Frederick) develops aerosol animal models of disease caused by high-consequence pathogens within animal biosafety level 4 (ABSL-4) containment laboratories. Using advanced technologies within the aerobiology field, this section provides high experimental reproducibility to ensure the best modeling possible.
Developing, characterizing, and refining animal models are key to advancing medical countermeasures for high-consequence pathogens.
The electron microscopy laboratory at the Integrated Research Facility at Fort Detrick (IRF‑Frederick) has a variety of capabilities for the analysis of biological samples at an ultrastructural level.
In vivo imaging is gaining increasing interest for the characterization of infectious diseases, including the ones caused by high-consequence pathogens.
The virology team at the Integrated Research Facility at Fort Detrick (IRF‑Frederick) has extensive expertise working with a range of high‑consequence viral pathogens. Studies focus on gaining a deeper understanding of viral pathogenesis and advancing clinical approaches to assist in managing diseases.
The team leverages fundamental methodologies, such as: