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Developing, characterizing, and refining animal models are key to advancing medical countermeasures for high-consequence pathogens.
The core services group at the Integrated Research Facility at Fort Detrick (IRF Frederick) provides cell culture, hematology, hemostasis, clinical chemistry, microbiology, and molecular virology support for monitoring animals in infectious disease studies.
In vivo imaging is gaining increasing interest for the characterization of infectious diseases, including the ones caused by high-consequence pathogens.
The In Vitro Assessment for Antimicrobial Activity program provides capability in a broad range of in vitro assessments to evaluate promising candidate countermeasures for antimicrobial activity against microbial pathogens and vectors, including those derived from clinical speci
The pathology department and histology laboratory at the Integrated Research Facility at Fort Detrick (IRF‑Frederick) work together to develop and use established animal models of high-consequence emerging human viruses to study disease pathogenesis and facilitate countermeasure development under
This contract program supports the development and refinement of animal models and animal replacement technologies and provides in vivo preclinical testing services, ranging from screening and proof-of-concept to GLP efficacy studies.
The Therapeutic Development Services program offers a collection of preclinical services to support the development of products intended for use in the cure, mitigation, diagnosis, or treatment of disease caused by a pathogen or certain toxins.
The Vaccine Development Services program offers a collection of preclinical services to support the development of vaccines intended for use in the investigation, control, prevention, and treatment of a wide range of infectious agents (other than HIV).
The virology team at the Integrated Research Facility at Fort Detrick (IRF‑Frederick) has extensive expertise working with a range of high‑consequence viral pathogens.