Resources for Researchers

NIAID offers many resources to support your research, including reagents, model organisms, and tissue samples, to name just a few. Use the filters under Filter Search Results to narrow your search, or simply enter specific search terms in the search field.

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HIV/AIDS
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The ACTG NL consists of Core Laboratory groups in immunology, pharmacology, virology and TB.

The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.

The ChemDB database contains information extracted from scientific literature on the structure and activity of compounds that have been tested against HIV, opportunistic pathogens and TB.

This contract provides gap-filling support services for HIV prevention drug developers including academic (investigators), for-profit and not-for-profit small and large companies, and other product innovators (henceforth identified as Sponsors) for the development of HIV non-vaccine biomedical pr

The RSC Public Website, run by the DAIDS Regulatory Support Center (RSC) contractor, has been used in the DAIDS community for over 10 years and is a primary platform to communicate updates to templates, process changes, and other information needed by the RSC research community.

Repository of specimens collected as part of the DAIDS VAX004 Clinical Trial.

The HIV Database & Analysis Unit provides an integrated repository of HIV sequence and immunology published data, by curating & maintaining a relational database with searchable web access for the scientific community; and (ii) develop web-based computation analysis methods and tools for

This service can be used to develop and perform a variety of analytical assays to assess the properties of drug substances and their formulations.

This service provides follow-up studies of products which already have been evaluated in a biochemical or cell-based assay and shown to possess an activity profile that warrants further development of the product as an HIV therapeutic.

This service provides evaluation of products in animal efficacy models. A product must demonstrate a potent and selective activity profile in vitro against the HIV strain used in the model prior to its acceptance as a candidate for this service.

This service can be used to provide pharmacokinetic and safety assessments of products in mice, rats, rabbits, dogs, and nonhuman primates.

This service program supports the development and manufacture, of a wide variety of pharmaceutical dosage formulations, including tablets, capsules, semi-solid preparations, injectibles, and sustained-release products. If requested, manufacturing can be done under GMP.

The HVTN shares data and specimens collected in its studies with investigators who would like to use our materials to answer research questions related to vaccinology, immunology, or HIV/AIDS.

HVTN provides structured mentorship and project funding to investigators working on HIV vaccines.

This service provides chemical synthesis of lead compounds for use in additional drug development studies. Compounds must previously have been successfully synthesized to be candidates for this service. Synthesis of new analogs is not supported.

The HIV Prevention Trials Network (HPTN) offers two scholarship programs for early-career investigators funded through a supplement from the National Institute of Allergy and Infectious Diseases (NIAID) and the National Institute on Drug Abuse (NIDA).

The Human Tissue and Organ Research Resource (HTORR) program provides normal and diseased human tissues to investigators at research centers.  HTORR supports the procurement, preservation, and distribution of human tissue and organs for basic and clinical research.  While the resource maintains a

The International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Early Career Investigator Mentored Research program aims to support the development of early career investigators to enter the field of maternal/child HIV research and advance the mission of the IMPAACT Network.

The main purpose of the International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) Laboratory Center is to support the network’s scientific agenda by providing state of the art laboratory testing in support of clinical trials, new works concept sheets (NWCS), and data analysis con

A common data model for sharing observational HIV data has been developed by the International epidemiology Databases to Evaluate AIDS (IeDEA). The IeDEA DES is used by the seven operational regions of IeDEA to exchange data with each other for collaborative research studies.

The Markedly Accelerating Research with Knowledge of Tuberculosis Biomarkers (MARK-TB) has created a collaborative biobank in order to accelerate the development of new drugs and treatments for tuberculosis by validating and exploring biomarkers of response to TB drug treatments. The biobank will

The Microbicide Trials Network (MTN) is a NIAID-funded worldwide collaborative clinical trials network focused on preventing the sexual transmission of HIV. The MTN accepts concepts for new protocols, ancillary study proposals, secondary data analysis requests, and dataset requests.

This service provides evaluation of products that have already been evaluated in a biochemical or cell-based assay and shown to possess an activity profile that warrants further development as a microbicide.

The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles.

The MACS collects and stores a variety of biological specimens. Inventory may be housed at the national level or a subset at the local level. The MACS Center for the Coordination and Analysis of MACS (CAMACS) coordinates and facilitates completion of specimen requests.