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3D Reconstruction via Stereoscopy for the Study of Mosquito Swarms includes information on a simple method used recently to localize individual Anopheles gambiae in a swarm via stereoscopic image analysis of video footage swarms recorded in Doneguebougou, Mali.
The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.
The Chicago Center for Functional Annotation (CCFA) is defining gene function on multiple scales, using a multi-disciplinary set of cellular, genetic, molecular, and biochemical approaches.
FLUTE is a Functional Genomics Center funded by NIAID, with the goal of discovering the roles of genes from Mtb with previously unknown functions. In addition FLUTE aims to establish an efficient pathway for identifying gene function that could serve as a paradigm for other bacterial species.
GUNK center is part of the NIAID Functional Genomics Program. This center was created to investigate the role of previously uncharacterized genes of A. baumannii in its ability to cause human disease. Three projects have been established to:
The GCID use and develop or improve innovative applications of genomic technologies, such as RNA sequencing and metagenomics, and provide rapid and cost-efficient production of high-quality genome sequences of microorganisms, invertebrate vectors of infectious diseases, and hosts and host microbiomes. Multiple strains and isolates of specific microbial species, populations and communities have been and continue to be sequenced.
Heterogeneity in Human Immune Cells is a website providing interactive figures (iFigs) for a recent study of protein expression heterogeneity in human immune cells conducted by Dr.
The HIV Database & Analysis Unit provides an integrated repository of HIV sequence and immunology published data, by curating & maintaining a relational database with searchable web access for the scientific community; and (ii) develop web-based computation analysis methods and tools for
The Immcantation framework is developed as a start-to-finish analytical ecosystem for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires from high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.
ImmPort is a Web portal that contains data from NIAID-funded immunology studies, including basic research and clinical trials. The portal provides online tools that allow users to analyze the data and visualize the results.
This free resource offers easy searching of experimental data characterizing antibody and T cell epitopes studied in humans, non-human primates, and other animal species.
The ImmuneSpace database is currently composed of 21 studies covering 10 types of assays and 2,500 total participants.
The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles.
The MACS collects and stores a variety of biological specimens. Inventory may be housed at the national level or a subset at the local level. The MACS Center for the Coordination and Analysis of MACS (CAMACS) coordinates and facilitates completion of specimen requests.
The portal brings together some exciting features including: links to BCBB’s training resources; a section of scripts, code, and programs created by NIAID researchers downloadable from GitHub; and a curated calendar of events with entries focused on bioinformatics and computational biology.
This core serves as a national resource for the long-term care and study of animals after irradiation, since 2007. The Radiation Late Effects Program facilitates the conduct of late-stage preclinical studies of mitigators of radiation damage in nonhuman primates.
The Orfeome Project is part of the NIAID-supported Functional Genomics Program.
The primary objective of the Clinical Studies Support Team (CSST) is to develop and foster overseas relationships through the support of research studies and clinical trials.
The PapillomaVirus Episteme (PaVE) provides highly organized and curated papillomavirus genomics information and tools to the scientific community for research on the Papillomaviridae family of viruses. The PaVE consists of a database and web applications that support the storage, annotation, analysis, and exchange of information. To the extent possible, the PaVE adopts an open source software approach and emphasizes integration and reuse of existing tools.
The Primary Immunodeficiency (PI) Diseases Registry collects validated data on all PI diagnoses from patients who give Informed Consent. The de-identified data in the registry is freely disseminated to those with research questions about PI diseases.
This Gene Set Enrichment-type test designed for analysis of microarray and RNASeq data is designed to provide a faster, more accurate, and easier to understand test for gene expression studies. QuSAGE extends previous methods with a complete probability density function (PDF).
The Structural Genomics Centers for Infectious Diseases provide the research community with: 3-D protein structures and protein-ligand complexes; Sequence-verified clones and peptides; Services that deliver requested 3-D structure determination; and Molecular screening of proteins in complex with inhibitors, cofactors and substrate analogs
The Systems Biology Consortium for Infectious Diseases is a community of systems biologists who integrate experimental biology, computational tools and modeling across temporal and spatial scales to improve our understanding of infectious disease
The NIAID TB Portals Program is a multi-national collaboration for tuberculosis (TB) data sharing and analysis to advance TB research.
TrialShare is a transformative approach to data-sharing that enables clinical trial transparency.