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NIAID Clinical Trials Data Repository, AccessClinicalData@NIAID, is an NIAID cloud-based, secure data platform that enables sharing of and access to anonymized individual, patient level clinical data sets from NIAID sponsored clinical trials to harness the power of data to generate new knowledge
The specimen repositories are a collaboration between the ACTG and IMPAACT clinical trial networks to make the large body of specimens collected for HIV research available to investigators.
The NIAID-funded Bioinformatics Resource Centers provide data-driven, production-level, sustainable computational platforms to enable sharing and access to data, portable computational tools, and standards that support interoperability for the infectious diseases research community.
The Chicago Center for Functional Annotation (CCFA) is defining gene function on multiple scales, using a multi-disciplinary set of cellular, genetic, molecular, and biochemical approaches.
Clinical Study Support Team (CSST) is a deployable team with the primary objective of developing and fostering overseas relationships through the support of research studies and clinical trials involving pathogens of high consequence.
The RSC Public Website, run by the DAIDS Regulatory Support Center (RSC) contractor, has been used in the DAIDS community for over 10 years and is a primary platform to communicate updates to templates, process changes, and other information needed by the RSC research community.
FLUTE is a Functional Genomics Center funded by NIAID, with the goal of discovering the roles of genes from Mtb with previously unknown functions. In addition FLUTE aims to establish an efficient pathway for identifying gene function that could serve as a paradigm for other bacterial species.
GUNK center is part of the NIAID Functional Genomics Program. This center was created to investigate the role of previously uncharacterized genes of A. baumannii in its ability to cause human disease. Three projects have been established to:
Heterogeneity in Human Immune Cells is a website providing interactive figures (iFigs) for a recent study of protein expression heterogeneity in human immune cells conducted by Dr.
The HIV Database & Analysis Unit provides an integrated repository of HIV sequence and immunology published data, by curating & maintaining a relational database with searchable web access for the scientific community; and (ii) develop web-based computation analysis methods and tools for
The Immcantation framework is developed as a start-to-finish analytical ecosystem for large-scale characterization of B cell receptor (BCR) and T cell receptor (TCR) repertoires from high-throughput adaptive immune receptor repertoire sequencing (AIRR-seq) datasets.
ImmPort is a Web portal that contains data from NIAID-funded immunology studies, including basic research and clinical trials. The portal provides online tools that allow users to analyze the data and visualize the results.
This free resource offers easy searching of experimental data characterizing antibody and T cell epitopes studied in humans, non-human primates, and other animal species.
The ImmuneSpace database is currently composed of 21 studies covering 10 types of assays and 2,500 total participants.
The Microbicide Trials Network (MTN) is a NIAID-funded worldwide collaborative clinical trials network focused on preventing the sexual transmission of HIV. The MTN accepts concepts for new protocols, ancillary study proposals, secondary data analysis requests, and dataset requests.
The Multicenter AIDS Cohort Study (MACS) is an ongoing prospective study of the natural and treated histories of HIV-1 infection in homosexual and bisexual men conducted by sites located in Baltimore, Chicago, Pittsburgh and Los Angeles.
The MACS collects and stores a variety of biological specimens. Inventory may be housed at the national level or a subset at the local level. The MACS Center for the Coordination and Analysis of MACS (CAMACS) coordinates and facilitates completion of specimen requests.
The portal brings together some exciting features including: links to BCBB’s training resources; a section of scripts, code, and programs created by NIAID researchers downloadable from GitHub; and a curated calendar of events with entries focused on bioinformatics and computational biology.
This core serves as a national resource for the long-term care and study of animals after irradiation, since 2007. The Radiation Late Effects Program facilitates the conduct of late-stage preclinical studies of mitigators of radiation damage in nonhuman primates.
The Orfeome Project is part of the NIAID-supported Functional Genomics Program.