Southeast Asia Malaria Research Center
Co-Principal Investigators: Liwang Cui, Ph.D. and Jetsumon Sattabongkot, Ph.D.
Lead Institution: University of South Florida, Tampa
Award date: original award in 2010; renewed in 2017
- Myat Phone Kyaw, Myanmar Medical Association (Saranath Lawpoolsri - Co-leader, Mahidol University)
- Jetsumon Sattabongkot, Mahidol University (Daibin Zhong – Co-Leader, University of California, Irvine)
- Liwang Cui, Pennsylvania State University
- Baomin Wang, China Agricultural University
- China Agricultural University, Beijing, China
- China Medical University, Shenyang, China
- Myanmar Medical Association, Yangon, Myanmar
- Kunming Medical University, Yunnan Province, China
- Mahidol University, Bangkok, Thailand
- University of California, Irvine, CA
The central goal of the Southeast Asia ICEMR is to improve understanding of how mobile human populations, parasite drug resistance, and mosquito biology contribute to continuous malaria transmission at international borders so that innovative control strategies can be developed. The Center will achieve this goal by:
- Obtaining detailed knowledge of the malaria epidemiology through surveillance to enable targeted malaria control
- Identifying the roles of major vector species in malaria transmission and determining genetics of insecticide resistance and biting behavior change
- Determining the dynamics and mechanisms of antimalarial drug resistance
- Developing point-of-care tools for monitoring antimalarial drug quality to ensure that quality drugs are deployed
There were 1.5 million confirmed cases of malaria in Southeast Asia in 2015, according to the World Health Organization. The regional ICEMR will bring together diverse expertise from the United States, China, Myanmar and Thailand to address urgent problems that are relevant to both regional and global malaria control.
View Associated sites for the Southeast Asia ICEMR in a larger map
Map description: Associated sites in China (Yunan Province), Thailand (Tha Song Yang), Myanmar (Chin State, Mon State, Kayin State, Kachin State)
Select Publications from the 2010 Award
- Chang X et al. Multiple resistances and complex mechanisms of Anopheles sinensis mosquito: a major obstacle to mosquito-borne diseases control and elimination in China. PLoS Negl Trop Dis. 2014. 8, e2889.
- Yuan L et al. Therapeutic responses of Plasmodium vivax malaria to chloroquine and primaquine treatment in northeastern Myanmar. Antimicrob Agents Chemother. 2015. 59, 1230-1235.
- Lo E et al. Molecular inference of sources and spreading patterns of Plasmodium falciparum malaria parasites in internally displaced persons settlements in Myanmar-China border area. Infect Genet Evol. 2015. 33, 189-196.
- Wang Y et al. Clinical efficacy of dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria at the China-Myanmar border. 2015. Am J Trop Med Hyg. 93, 577-583.