West Africa International Center of Excellence for Malaria Research

Multidisciplinary Research for Malaria Control and Prevention in West Africa

Principal Investigator: Seydou Doumbia, M.D., Ph.D.
Lead Institution: University of Sciences, Techniques, and Technology of Bamako, Mali

Seydou Doumbia

Seydou Doumbia, M.D., Ph.D.

Award date: 2017

Project Leads

  • Nafomon Sogoba, University of Sciences, Techniques, and Technology of Bamako
  • Mahamadou Diakite, University of Sciences, Techniques, and Technology of Bamako
  • Sekou Fantamad Traore, University of Sciences, Techniques, and Technology of Bamako

Collaborating Institutions

  • Tulane University, New Orleans, LA
  • University of Georgia, Athens, GA
  • University of Miami, Miami, FLA
  • London School of Hygiene and Tropical Medicine, London, UK
  • University of Copenhagen, Denmark
  • Wellcome Trust Sanger Institute, Hinxton Cambridge, UK
  • Malaria Immunology Section, Laboratory of Malaria and Vector Research, NIAID

Research Areas

The overall goal of this ICEMR is to understand the variable effectiveness of current malaria control interventions in different ecological settings of West Africa.  This goal will be accomplished by performing field and laboratory studies of the epidemiology, entomology (transmission), immunology and pathogenesis of malaria to characterize and understand:

  • The heterogeneity of malaria infection, disease and transmission
  • The effects of control strategies on malaria transmission and pathogenesis
  • The major obstacles to improving malaria control and potentially eliminating malaria, including drug and insecticide resistance

Regional Impact

Sub-Saharan Africa continues to carry a disproportionately high share of the global malaria burden. of malaria deaths. Moreover, incidence remains high but stable in some settings while rebounding in others after a long period of decrease associated with intensive deployment of malaria control tools. This Center proposes to link the different aspects of malaria transmission and disease into a unified whole, adding the ability to distinguish the contributions of different malaria control interventions on parasite population and immune responses as well as the seasonal and geographical distribution of anopheline mosquitoes. Understanding the factors relating entomological and epidemiological patterns of transmission will provide more definitive guidelines for malaria control efforts in Mali and in West Africa.

View Associated sites for the Mali ICEMR in a larger map

Map description: Associated sites for the Mali ICEMR: Dangassa, Dioro, Sirakorola

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Featured Research

 

Content last reviewed on June 27, 2017