Hepatitis C Clinical Research Studies

You can help NIAID advance hepatitis research by volunteering to participate in a clinical study. There is no charge for study-related medical care, including study visits, medications, treatments, and procedures. Volunteers may be compensated for time and travel.

The following are selected studies supported by NIAID and recruiting people with hepatitis C. The links lead to full study titles, descriptions, and contact information. 

Evaluating the Safety and Effectiveness of Interferon-Free Treatment of Hepatitis C Virus Infections in HIV-Coinfected Adults on Antiretroviral Therapy (NCT02194998) 
The purpose of this study is to evaluate the safety, tolerability, and effectiveness of IFN-free HCV treatment in HIV/HCV coinfected adults ages 18-70 years who are taking antiretroviral (ARV) therapy.

Effects of Persistent Innate Immune Activation on Vaccine Efficacy (NCT02429583) 
This study will investigate the effects of chronic HCV infection and corresponding innate immune activation on the immune response to HBV vaccination to enhance our understanding of the immune effects of chronic viral infection, establish factors that determine effective vaccine responses, and help guide vaccination strategies for HCV patients and other individuals with chronic inflammatory disease.

Effects of Chronic Viral Infection on Immune Response to Zoster Vaccination (NCT02590068)  
This study aims to identify the innate and adaptive immune response to zoster vaccination in adults ages 50-70 years. Half of the participants will be individuals with chronic hepatitis C, while the other half with healthy volunteers.

Read about the NIAID role in viral hepatitis research.

Content last reviewed on August 4, 2017