Seasonal influenza, or flu, is a highly contagious respiratory illness caused by influenza viruses that infect the nose, throat and lungs. The two main types of influenza viruses—types A and B—are the viruses that typically spread in people (human influenza viruses) and cause annual flu outbreaks. Each year, influenza causes millions of illnesses worldwide and, in the United States, results in thousands of hospitalizations and deaths. Influenza is especially dangerous for people 65 years and older, young children and people with certain health conditions, such as heart disease or asthma.
An influenza pandemic occurs when a new influenza virus emerges that is able to infect and spread easily from person to person and to which most of the global population does not have immunity. The last known influenza pandemic occurred in 2009 with the emergence of the H1N1 influenza virus. Research to find new and improved ways to diagnose, treat and prevent seasonal influenza and novel influenza viruses with pandemic potential is essential to protecting the public health.
Highlights
Features of H5N1 Influenza Viruses in Dairy Cows May Facilitate Infection, Transmission in Mammals
A series of experiments with highly pathogenic H5N1 avian influenza (HPAI H5N1) viruses circulating in infected U.S. dairy cows found that the viruses may differ from previous HPAI H5N1 viruses and that they may possess features that could facilitate infection and transmission among mammals, although currently they do not appear capable of respiratory transmission.
NIAID Research Agenda for 2024 H5N1 Influenza
NIAID has mobilized its intramural and extramural-supported research infrastructure to provide scientific support to the U.S. Department of Agriculture (USDA) and the Department of Health and Human Services (HHS).
Infectious H5N1 Influenza Virus in Raw Milk Rapidly Declines with Heat Treatment
NIAID scientists found that levels of infectious H5N1 influenza virus in raw milk rapidly declined with heat treatment in a lab setting; however, small, detectable amounts of virus remained in raw milk samples with high virus levels when treated at 72 degrees Celsius for 15 seconds.
News Releases
NIAID Now Blog
Funded Research News
- T Cells May Offer Some Protection in an H5N1 “Spillover” Scenario
September 16, 2024
Volunteer for Clinical Trials
Find out how you can make a difference by participating in clinical research to find new and improved ways to understand, detect, treat and prevent influenza.
Find featured NIAID influenza studies.
Visit ClinicalTrials.gov for a full list of influenza studies funded by NIH.
Related Public Health and Government Information
To learn about risk factors for the flu and current prevention and treatment strategies visit the MedlinePlus flu site.