Type 1 Diabetes

NIAID is committed to advancing the understanding of autoimmune diseases such as type 1 diabetes and to conducting clinical studies to develop effective prevention and treatment strategies. The following are selected studies supported by NIAID and recruiting people with type 1 diabetes or their relatives. The links lead to full study titles, descriptions, site locations and contact information.

Pathway to Prevention Study (NCT00097292)
The goal of this study is to enhance the understanding of the demographic, immunologic, and metabolic characteristics of individuals at risk for developing type 1 diabetes. Individuals 1 to 45 years old who have an immediate family member with type 1 diabetes (such as a child, parent, or sibling) or individuals 1 to 20 years old who have an extended family member with type 1 diabetes (such as a cousin, niece, nephew, aunt, uncle, grandparent, or half-sibling) may be eligible to volunteer.

Type 1 Diabetes Extension Study (T1DES) (NCT02734277)
The goal of this study is to further the understanding of the immunologic mechanisms underlying maintenance and loss of beta cell function by evaluating the relationship between longitudinal changes in beta cell function and changes over time in biomarkers known to be associated with a response to immune modulating treatments which were used in prior clinical trials. Participants in selected new-onset type 1 diabetes studies conducted by the Immune Tolerance Network may be eligible to volunteer.


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Participating in Research

Watch a series of short informational videos about participating in clinical trials. These videos are intended to help potential participants understand how research works, what questions they should consider asking, and things to think about when deciding whether or not to participate in a study.