Yes. When receiving an application, NIH staff make sure the key parts are there, such as the face page, budget page, and Research Plan.
Later, before the scientific review officer (SRO) sends your application to reviewers, he or she looks at it more thoroughly to make sure it's complete. The SRO will also verify that your application is responsive to any requirements specific to a given funding opportunity announcement. Read SROs Assess Completeness, Assign Reviewers to learn more.