News From NIAID’s HIV Clinical Trials Networks

Funding News Edition: December 16, 2020
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Two weeks ago, NIAID announced the clinical investigators and institutions that will lead our four HIV clinical trials networks over the next seven years to conduct the innovative clinical research needed to accelerate progress against the HIV epidemic. NIAID also awarded grants to 35 institutions selected as HIV clinical trials units (CTUs).

The four networks will direct, coordinate, and conduct NIH-funded clinical research worldwide in close coordination with one another, NIAID, NIH, industry, and non-governmental research organizations. They are:

HIV Vaccine Trials Network (HVTN)—developing a safe, effective, and durable preventive HIV vaccine

HIV Prevention Trials Network (HPTN)—advancing an array of non-vaccine HIV prevention products and strategies to meet the needs and preferences of diverse populations worldwide

AIDS Clinical Trials Group (ACTG)—developing and evaluating potential new treatments and cure strategies for HIV and HIV-related complications and co-infections in adults

International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT)—developing and evaluating potential new treatments and cure strategies for HIV and HIV-related complications and co-infections in infants, children, adolescents, and pregnant and postpartum women

Each network is coordinated by a Leadership and Operations Center (LOC), a Laboratory Center (LC), and a Statistical and Data Management Center (SDMC).

The 35 CTUs will provide scientific and administrative expertise, as well as the infrastructure to conduct clinical trials within the networks. Each CTU supports up to eight clinical research sites. All told, the CTUs support 101 clinical research sites in 18 countries, including 45 sites in the United States.

Learn More

Find the names and institutions of the awardees to lead the networks at NIH Announces Restructured HIV Clinical Trials Networks.

The NIAID webpage HIV/AIDS Clinical Trials Units and Clinical Research Sites lists the principal investigators and institutions of the CTU awards and displays a map of the corresponding HIV/AIDS clinical research sites.

Every seven years, NIH competitively renews its funding of the HIV/AIDS clinical trials networks. The purpose and approach driving that process is described at Refining the HIV Clinical Trials Enterprise.

How To Participate

If you are an HIV/AIDS researcher interested in collaborating with NIAID and its partners, go to HIV/AIDS Information for Researchers to explore available funding opportunities, networks, and resources available to you.

Contact Us

Email us at for help navigating NIAID’s grant and contract policies and procedures.

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