Apply for Funds To Develop Pediatric Radiation Medical Countermeasures, Animal Models, and Biodosimetry Tools

Funding News Edition: August 19, 2020
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NIAID’s Radiation and Nuclear Countermeasures Program (RNCP) seeks to advance the study of pediatric medical countermeasures (MCMs) and biodosimetry tools through a new Notice of Special Interest (NOSI): Notice of Availability of Funds for Administrative Supplements for Pediatric Radiation/Nuclear Animal Models, MCM, Biodosimetry Development.

Scientific Areas of Interest

The NOSI encourages existing RNCP grant awardees to propose research that advances pediatric MCM and biodosimetry tool development to mitigate the effects of Acute Radiation Syndrome and Delayed Effects of Acute Radiation Exposure. Applicants should propose research in the following areas:

  • Radiation MCM development and testing for possible pediatric use
  • Pediatric radiation/nuclear animal model development
  • Radiation biomarkers and/or biodosimetry tools developed using pediatric samples for reference and validation

Although NIAID’s RNCP sponsors research and product development focusing on drugs administered post-irradiation, the primary focus has been on adults. Most MCMs lack pediatric components due to limited availability of pediatric models. In addition, pediatric samples needed to validate biodosimetry tools for this special population are difficult to obtain.

NIAID and the Biomedical Advanced Research and Development Authority hosted a workshop on “Pediatric Radiation and Chemical Medical Countermeasures: Policy and Regulatory Considerations” in 2015. This workshop highlighted the limited advancement in this area and the need for funding focused on developing MCMs and biodosimetry tools.

Administrative Supplements

Applicants will be awarded administrative supplements to meet additional costs associated with pediatric model development, sample collection, and analysis within the scope of the approved award.

We strongly encourage applicants to discuss their supplement project proposals with their NIAID program official before submitting to ensure that the proposed research is within the scope of the approved award. Your application should contribute to a greater understanding of the health and well-being of the pediatric population after a radiation incident.

How To Apply

Apply to this initiative using the following funding opportunity announcement referenced in the NOSI: Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp, Clinical Trial Optional).

You will need to identify the NOSI in your application. To do so, include “NOT-Al-20-061” (without quotation marks) in the Agency Routing Identifier field (box 4B) of the SF 424 R&R form. Note that applicants must follow all instructions in the SF 424 (R&R) Application Guide  and PA-18-591. Applications without this information in box 4B will not be considered. 

There is one annual due date over three years–November 1, 2020, 2021, and 2022. The proposed supplement budget cannot exceed $100,000 in total costs.

Contact Information

Direct questions to RNCP’s Dr. Lanyn Taliaferro, NIAID’s scientific/research contact.

Contact Us

Email us at deaweb@niaid.nih.gov for help navigating NIAID’s grant and contract policies and procedures.

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