NIAID has helped colleagues at Houston Methodist Hospital establish a “layered” big-data approach to analyze microbial genetic changes that can make some bacteria extremely dangerous to people.
Researchers have identified immunologic factors that predispose certain children to recurrent tonsil infections. While nearly everyone is exposed to strep bacteria during childhood, only some children develop recurrent tonsillitis. New findings uncover immune responses linked to recurrent tonsillitis and suggest a potential strategy for development of a vaccine to prevent strep infections.
PATRIC is one of six NIAID-funded Bioinformatics Resource Centers (BRCs) for Infectious Diseases and focuses on bacterial species. The BRCs compile large datasets in a standardized way, allowing scientists to perform analyses more efficiently. This can include assessing the function of specific genes, identifying markers for diagnosing a particular bacterial infection, or discovering new bacterial resistance mechanisms.
NIAID supports biomedical research to combat the growing public health threat of antimicrobial resistance. Check out NIAID’s image library of antimicrobial-resistant microbes and related graphics.
NIAID makes many resources available to researchers, such as reagents, model organisms, and tissue samples. Now it’s even easier to find these resources on our site using the Resources for Researchers feature.