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July 14, 2021
A study funded by the National Institute of Allergy and Infectious Diseases contributes to the evidence for a new guideline on how to induce remission and treat relapse of a rare, severe autoimmune disease called ANCA-associated vasculitis.
February 24, 2020
Identifying predictors of autoimmune disease flare-ups could aid treatment for these conditions by allowing doctors to intervene before symptoms worsen. Recognizing immune system attributes that forecast a healthy person’s response to vaccination or infection would help researchers develop new vaccines. A new NIAID study connects these seemingly distinct avenues of research.
February 24, 2020
Medicine has recognized rare autoinflammatory diseases for just over 20 years, and while early diagnosis and treatment can improve patient outcomes, similar symptoms across different diseases can make them difficult to diagnose and manage. Now, NIAID scientists and their colleagues have developed an integrated approach that combines next-generation genetic sequencing with advanced diagnostic techniques to characterize inflammatory responses. In doing so, investigators discovered three new autoinflammatory diseases.
September 06, 2019
NIAID-funded scientists studying autoimmune diseases have identified an unexpected protective function for a type of immune cell normally known to destroy cancerous or infected cells. In a mouse model of multiple sclerosis, these cells helped reduce the severity of the disease and could one day become useful therapeutic targets in treating autoimmune diseases in humans.
May 31, 2019
Celiac disease is an autoimmune disease in which gluten in the diet triggers an immune response that damages the small intestine. In people with this disease, eating gluten activates CD4+ T cells, a type of immune cell that helps to promote immune responses. Celiac disease is one of only a few autoimmune diseases in which a specific triggering substance has been identified. Therefore, studying this disease may provide crucial insights into the development of autoimmune disease more broadly.
April 02, 2019
NIAID has many opportunities available through training programs, whether you are a high school student or an early-career scientist or anything in between. Trainees conduct research focused on infectious, immunologic, and allergic diseases in NIAID laboratories, providing a unique scientific research training environment in basic, translational, and clinical research.
February 26, 2019
Bone marrow transplants can be necessary for treating cancer and many other illnesses, but the process can be grueling. By using an antibody-drug combination to kill existing bone marrow stem cells, NIAID scientists were able to drastically improve bone marrow and skin transplant outcomes in mice.