31 Results

Hepatitis B and C—A Closer Look at NIAID Research to Accelerate Elimination

Viral hepatitis is an inflammatory liver disease caused by infection with any of the known hepatitis viruses—A, B, C, D, and E. Most of the global viral hepatitis burden is from hepatitis B and C, which affect 354 million people and result in 1.1 million deaths annually. The Centers for Disease Control and Prevention estimates that in 2020 there were 14,000 and 50,300 new acute infections of...

Final IAS 2023 Conversations—HIV & STI Prevention, Stigma, and U=U

As the International AIDS Society’s 12th Conference on HIV Science (IAS 2023) conference drew to a close on Wednesday, continued our conversations about the latest research being presented, with updates on post-exposure prophylaxis for STIs (Doxy-PEP), implementation of HIV PrEP, and the effectiveness of U=U.

IAS 2023—HIV Vaccines, bNAbs, and an Update from NIH’s Office of AIDS Research

This blog is cross-posted from 

On Tuesday at the International AIDS Society’s 12th Conference on HIV Science (IAS 2023), continued our conversations about research highlights, including a focus on the latest about HIV vaccines. We also heard an update from the NIH Office of AIDS Research.

NIH’s Carl Dieffenbach, Ph.D., Director of the Division of AIDS at the National...

Conversations at the Opening of IAS 2023

The International AIDS Society’s 12th Conference on HIV Science (IAS 2023) opened Sunday, with thousands of scientists, policy leaders, and advocates gathered to present and discuss the latest advances in HIV research.’s coverage of the conference began with two video conversations looking ahead to the exciting research that will be presented.

IAS Conference Highlights—Heart Disease Prevention for People with HIV, Long-acting HIV Prevention and Treatment

During the first full day of sessions at the International AIDS Society’s 12th Conference on HIV Science (IAS 2023), shared conversations on important study findings about reducing cardiovascular disease among people with HIV and the latest developments with long-acting prevention and treatment options that could one day become safe and effective alternatives to daily oral pills.

Register Now! Live with Leadership—A Conversation Commemorating National HIV Vaccine Awareness Day

Register now to take part in an important conversation about National HIV Vaccine Awareness Day—an annual observation to recognize the many community members, health professionals, and scientists working together to develop a vaccine to prevent HIV. The Live with Leadership conversation will take place on Thursday, May 18, from 2:30–3:00pm ET.

Register Now!

This engaging...

Assessment of PrEP Eligibility Tool Among the General Population in Uganda

To reduce the spread of HIV infection, the World Health Organization (WHO) recommends pre-exposure prophylaxis (PrEP) in populations with an annual HIV infection incidence greater than 3%. Given that the annual HIV incidence in Uganda is estimated at 0.40% (0.46% among females and 0.35% among males), there are people who may have a higher HIV risk and may benefit from PrEP but are not targeted for...

NIH Continues Investment in HIV Prevention, Therapy and Cure with $34 Million Award

The National Institutes of Health has awarded approximately $34 million annually over the next five years to fund six independent Centers for HIV Structural Biology

HIV Research Update from CROI 2022 with NIH’s Dr. Carl Dieffenbach—Cancer Prevention, Aging, and the Future of HIV Prevention & Treatment

As the 2022 virtual Conference on Retroviruses and Opportunistic Infections came to a close, NIAID's Dr. Carl Dieffenbach joined for a video conversation on February 24 to discuss important findings on cancer prevention in people with HIV, research on HIV and aging, and the future of HIV prevention and treatment. Dr. Dieffenbach is the Director of the NIAID Division of AIDS.

NIH’s Dr. Carl Dieffenbach Discusses Highlights of HIV Cure, Treatment and Prevention Research from CROI 2022

In an video conversation on February 16, NIAID's Dr. Carl Dieffenbach discussed some of the pivotal HIV research advances presented this week at the 2022 virtual Conference on Retroviruses and Opportunistic Infections (CROI 2022). Dr. Dieffenbach, who directs the Division of AIDS, covered developments in HIV cure, treatment and prevention research. Watch the conversation and read summaries of the study findings he discussed.

Maternal HIV Drug Resistance Is Associated with Mother-to-Child Transmission

Antiretroviral therapy of pregnant women and antiretroviral treatment of infants have greatly reduced the rate of mother-to-child HIV transmission, also referred to as vertical transmission. Nevertheless, although these improved rates have occurred in some countries, vertical transmission rates remain relatively high in others. This may be due to multiple factors, including access to testing, care...

The 2001 International Maternal Pediatric Adolescent AIDS Clinical Trial Network (IMPAACT) Study on Rifapentine and Isoniazid for Tuberculosis Prevention in Pregnant Women

Tuberculosis (TB) has a significant impact on maternal and infant health and is one of the leading causes of maternal death worldwide. Pregnant and postpartum women with latent TB are at a higher risk of developing active TB and pregnancy complications due to TB infection can result in babies with low birth weight, premature birth, and stillbirth. Additionally, maternal TB more than doubles the...

Two HIV Treatment Drugs Tested in Pregnant and Postpartum Women with HIV

For pregnant women living with HIV, antiretroviral treatment (ART) is recommended to treat the infection in the mother and prevent mother-to-child HIV transmission. However, pregnancy may affect the way antiretroviral drugs are metabolized and may result in rendering the drug less effective. Studies that address the pharmacokinetics (rates of distribution, absorption, metabolism, and excretion) of...

NIAID Observes HIV Vaccine Awareness Day 2021

While implementation of highly effective HIV treatment and prevention tools has reduced the HIV pandemic worldwide, development of a safe and even modestly effective vaccine would hasten progress toward a durable end of the HIV pandemic. Today, on HIV Vaccine Awareness Day, NIAID acknowledges both the progress that has been made in HIV vaccine development and the challenges that remain. We also reflect on how advances in HIV vaccinology paved the way for COVID-19 vaccine development.

Efficacy and Safety of Three Different ART Regimens during Pregnancy

Viral suppression of HIV during pregnancy is important for both maternal health and prevention of mother-to-child transmission. Antiretroviral therapy (ART) is an effective method to manage HIV, but rigorous studies on the safety and efficacy of different ART regimens in pregnant women have been limited. To address this, a recent phase 3 trial was conducted to compare three ART regimens...

World TB Day 2021—The Clock is Ticking

On World TB Day, the National Institute of Allergy and Infectious Diseases (NIAID) joins the World Health Organization and others in acknowledging the need for continued, concerted efforts to combat tuberculosis.

HIV Prevention Study Conducted in Different Geographic Regions Among At-risk Women, Men, and Transgender People

Although the spread of HIV has slowed down thanks to risk-reduction measures, prevention efforts, and oral antiretroviral preexposure prophylaxis (PrEP), there are more than 1.5 million new cases of the human immunodeficiency virus (HIV) each year worldwide. The Antibody Mediated Prevention trials included two clinical trial cohorts, to test the ability of the monoclonal antibody VRC01 to prevent...

Final HIV Prevention & Treatment Research Highlights from CROI 2021

NIH’s Dr. Carl Dieffenbach joined for a conversation about the latest HIV prevention and treatment research presented there.

HIV and COVID-19, Potential New HIV Prevention Tools, and More—Research Highlights from CROI 2021

NIH’s Dr. Carl Dieffenbach shared highlights from HIV research presented at the 2021 virtual Conference on Retroviruses and Opportunistic Infections.

Lower Incidence of HIV Infection among Women in Epidemic Settings with Initiation and Flexible Access to PrEP

Despite major advances in testing and treating HIV, including highly effective oral pre-exposure prophylaxis, there were 1.7 million new cases of HIV in 2019.  Fifty-nine percent of these occurred in sub-Saharan Africa, where a high proportion of newly infected individuals are women. In order to see if facilitating PrEP delivery decreased HIV transmission in these areas, a flexible care delivery...

NIAID-Supported Research Unveils Characteristics of Key Steps in HIV Life Cycle

New NIAID-funded research answers longstanding questions about key steps in HIV life cycle.

NIH Awards Will Advance HIV Implementation Research in U.S. Communities

NIH has awarded approximately $10 million to support implementation science research which aims to reduce new HIV diagnoses in the United States.

Large NIH Clinical Trial Illuminates Long-Term Health Effects of HIV

Initial data from a large NIH-supported clinical trial offer a detailed look at the health status of people aging with HIV around the world.

NIAID and Partners to Develop Antibody-Based Products for HIV Prevention and Treatment

NIAID and IAVI, a nonprofit scientific research organization, are collaborating to develop antibody-based products for HIV prevention and treatment.

Final HIV Research Highlights from AIDS 2020

In his final interview with at AIDS 2020: Virtual, NIAID's Dr. Carl Dieffenbach discussed HIV vaccine development, a new partnership to expedite development of HIV antibody combination products, NIH’s engagement in the Ending the HIV Epidemic initiative, and a look to what’s on the horizon in HIV research in the year ahead.


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