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Division of Allergy, Immunology, and Transplantation (DAIT)

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Some Reported Allergic Reactions to mRNA COVID-19 Vaccines Were Likely Stress Responses

February 27, 2023

Some responses to the mRNA COVID-19 vaccines reported as severe allergic reactions were likely a recently described, non-allergic condition called immunization stress-related response (ISRR), according to a study by investigators. The symptoms of ISRR can closely mimic those of a severe allergic reaction known as anaphylaxis, a potentially life-threatening, systemic allergic reaction in which the immune system releases a dangerous flood of chemicals.

White card with black text recording two doses of COVID-19 vaccine.

NIAID Researchers Identify Link Between Common Chemicals and Eczema

January 24, 2023

NIAID scientists have found an association between widely used chemicals called diisocyanates and atopic dermatitis, a chronic inflammatory skin disease commonly known as eczema.

Raised red lesions pepper skin of young child's leg

NIAID-Supported Studies Identify Universal Predictors of Antibody Response to Vaccination

January 10, 2023

Two recently published studies explain why some people respond better to vaccines than others and could guide the development of new strategies to enhance the antibody response to vaccination.

hand injects needle of syringe into shoulder muscle

Newly Discovered Species of Gut Bacteria May Cause Some Cases of Rheumatoid Arthritis

January 05, 2023

Research by NIAID grantees strongly suggests that immune responses to a newly discovered species of gut bacteria may cause some cases of a common autoimmune disease called rheumatoid arthritis. The findings were recently published in Science Translational Medicine.

Photo of hand affected by rheumatoid arthritis

Injectable Antiretroviral Medication Proves to be Effective in Preventing HIV Infection in Women

October 19, 2022

Women are disproportionately affected by HIV, with young women in sub-Saharan Africa three times as likely to be infected than young men in the same age group. In 2015, the World Health Organization (WHO) recommended that tenofovir-based pre-exposure prophylaxis (PrEP) be offered to high-risk individuals for prevention. As a result, oral PrEP has been introduced in more than 70 countries, including sub-Saharan Africa.

NIAID Recognizes October as Eczema Awareness Month

October 17, 2022

The National Institute of Allergy and Infectious Diseases, a part of NIH, stands with the scientific community in recognizing October as Eczema Awareness Month and acknowledging the need for continued research into possible cures and therapeutics.

Fernanda Young is a medical doctor in NIAID's Laboratory of Allergic Diseases

First FDA-Approved Treatment for Eosinophilic Esophagitis Has Roots in NIAID-Funded Research

September 15, 2022

The first Food and Drug Administration approval of a treatment for eosinophilic esophagitis, announced in May 2022, marked a vital achievement not only for people with the disease, but also for scientists including a NIAID grantee whose research helped lay a foundation for this milestone.

Illustration of an eosinophil

NIAID-Funded Adjuvant Improves Typhoid Vaccine Candidate in Animal Studies

August 17, 2022

An investigational typhoid vaccine containing a component developed with NIAID funding may overcome some of the shortcomings of available typhoid vaccines, according to a paper published in the journal Vaccine in June.

S. Typhi shown under a microscope

NIAID Research Informs Guideline for Treating People with ANCA-Associated Vasculitis

July 14, 2021

A study funded by the National Institute of Allergy and Infectious Diseases contributes to the evidence for a new guideline on how to induce remission and treat relapse of a rare, severe autoimmune disease called ANCA-associated vasculitis.

Image of vascular branches in the retina

Study of Infants with Severe Lung Infection Identifies Those at Highest Risk for Asthma

June 17, 2021

Nearly a third of infants who are hospitalized with a severe form of a common childhood lung infection called bronchiolitis develop asthma a few years later. However, clinicians have been unable to predict which infants with severe bronchiolitis are at high risk for developing asthma and to understand why. Now, a NIAID-funded study published in the journal Nature Communications has taken a step toward accomplishing this.

SEM of human RSV virions shedding from human lung epithelial cells

NIAID-Funded Research Leads to Approval of Drug for Acute Radiation Injury

February 09, 2021

NIAID-funded research has expanded the toolbox of medical countermeasures available in case a catastrophic event exposes people to high doses of radiation.

Microscopic image showing small, spiky platelets among larger, round red blood cells

New NIAID Study Examines Immune Responses in People Hospitalized with COVID-19

May 01, 2020

A new NIAID-supported study has begun to track the immune responses of people hospitalized with COVID-19 in 10 research sites across the United States.

3D print of a SARS-CoV-2 particle

Addressing Rare Diseases—Gene Therapy and Beyond

February 20, 2020

Information about NIAID’s commitment to addressing rare diseases through gene therapy and beyond.

Zebra-print ribbon, a symbol for awareness of primary immunodeficiencies and other rare diseases, on a plain white surface

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