Video—What Is Chronic Granulomatous Disease?

NIAID Now | July 29, 2019

Credit: NIAID

Bleach is a household staple for cleaning and sanitizing items from clothes to countertops. Within the human body, the immune system also harnesses the power of this disinfectant. White blood cells that ingest harmful bacteria and fungi produce bleach and other toxic chemicals to kill the pathogens and eliminate infection.

In chronic granulomatous disease, or CGD, this process does not occur as it should, leaving people with the condition susceptible to frequent and sometimes life-threatening bacterial and fungal infections. CGD is one of the many primary immune deficiency diseases—genetic disorders that impair the immune system—studied by NIH researchers.

In a new video, NIH scientists provide an overview of CGD, describe its symptoms and prevalence, and discuss how treatments for the condition have advanced. They also explain how studying CGD has not only helped people with this rare disease but also yielded insights into more common conditions.

Watch the video: 


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