March 19, 2021
A study to identify prenatal and early childhood markers of high risk for food allergy and atopic dermatitis, or eczema, as well as biological pathways that lead to these conditions, has begun. The observational study of children from birth to age 3 years will examine the origins of allergic disease by integrating interdisciplinary analyses of data from more than 260 biological and environmental samples and survey responses from each of 2,500 families.
September 9, 2020
An experimental treatment for eczema safely reduced disease severity and increased quality of life for children as young as 3 years old, NIH study shows.
August 14, 2020
New NIH-supported research shows how two common variations in the KIF3A gene cause an impaired skin barrier that allows increased water loss from the skin.
April 23, 2019
Scratching the skin triggers a series of immune responses culminating in an increased number of activated mast cells—immune cells involved in allergic reactions—in the small intestine, according to research conducted in mice. This newly identified skin-gut communication helps illuminate the relationship between food allergy and atopic dermatitis (a type of eczema), a disease characterized by dry, itchy skin.
February 20, 2019
Atopic dermatitis, a common inflammatory skin condition also known as allergic eczema, affects nearly 20 percent of children, 30 percent of whom develop food allergies. Scientists have now found that children with both atopic dermatitis and food allergy have structural and molecular differences in the top layers of healthy-looking skin near the eczema lesions, whereas children with atopic dermatitis alone do not.