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October 01, 2019
A new study published today online in Emerging Infectious Diseases suggests that transmission of a protozoan parasite from insects may also cause leishmaniasis-like symptoms in people. The parasite, however, does not respond to treatment with standard leishmaniasis drugs. The research was conducted by scientists at the Federal Universities of Sergipe and São Carlos, the University of São Paulo, and the Oswaldo Cruz Foundation, all in Brazil, along with investigators at the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S.
October 17, 2018
A surge in Lassa fever cases in Nigeria in 2018 does not appear to be linked to a single virus strain or increased human-to-human transmission, according to a genomic analysis published in The New England Journal of Medicine. Multiple institutions collaborated on the report, including the African Center of Excellence for Genomics of Infectious Diseases at Redeemer’s University in Ede, Nigeria; the Broad Institute of MIT and Harvard in Cambridge, Massachusetts; the Scripps Research Institute in La Jolla, California; and Tulane University in New Orleans, among others.
August 22, 2018
The Central Africa region is experiencing rapid urbanization and economic growth, and infrastructure development. These changes, while generally positive and welcome, also make the region more vulnerable to explosive infectious disease outbreaks, according to an international group of scientists.
August 16, 2018
Vaccinations have begun in a first-in-human trial of an experimental live, attenuated Zika virus vaccine developed by NIAID scientists.
August 10, 2018
Despite promising advances, important scientific questions remain unanswered in the effort to develop a safe and effective Ebola vaccine, according to members of an international Ebola research consortium. In a Viewpoint published in The Lancet, the experts review the current field of Ebola vaccine candidates and clinical trials and highlight key gaps in knowledge that need to be addressed by future research.
November 08, 2017
River blindness, or onchocerciasis, is a disease caused by a parasitic worm found primarily in Africa. The worm (Onchocerca volvulus) is transmitted to humans as immature larvae through bites of infected black flies. Symptoms of infection include intense itching and skin nodules. Left untreated, infections in the eye can cause vision impairment that leads to blindness. Mass distribution of ivermectin is currently used to treat onchocerciasis. However, this treatment can be fatal when a person has high blood levels of another filarial worm, Loa loa.
November 21, 2016
Scientists have sequenced the genome of the parasitic worm responsible for causing onchocerciasis—an eye and skin infection more commonly known as river blindness.