National Institutes of Health (NIH) and Colorado State University (CSU) scientists have provided experimental evidence supporting dromedary camels as the primary reservoir, or carrier, of Middle East respiratory syndrome coronavirus (MERS-CoV). The study, designed by scientists from CSU and NIH's National Institute of Allergy and Infectious Diseases, involved three healthy camels exposed through the eyes, nose and throat to MERS-CoV isolated from a patient. Each camel developed a mild upper respiratory tract infection consistent with what scientists have observed throughout the Middle East.
The researchers theorize that vaccinating camels could reduce the risk of MERS-CoV transmission to people and other camels; NIAID and others are supporting research to develop candidate vaccines for potential use in people and camels. The MERS outbreak, which began in 2012, continues throughout the Middle East. Since the outbreak began, NIAID researchers have focused on understanding how the virus causes disease and how it can be treated effectively. As of July 23rd, the World Health Organization has reported a total of 837 human cases of MERS-CoV infection, including at least 291 deaths.
D Adney et al. Replication and Shedding of MERS-CoV in Upper Respiratory Tract of Inoculated Dromedary Camels. Emerging Infectious Diseases DOI: 10.3201/eid2012.141280 (2014).
Vincent Munster, Ph.D., chief of the Virus Ecology Unit in the NIAID Laboratory of Virology, is available for interviews.
To schedule interviews, please contact Ken Pekoc, (301) 402-1663, firstname.lastname@example.org.