Researchers adapted a diagnostic test originally developed for prion diseases to detect a protein associated with Alzheimer’s disease and chronic traumatic encephalopathy. Read more.
Electron micrograph of clusters of tau protein.
Scientists reported that a drug initially developed to treat neurological diseases benefited a subset of patients with rare hypereosinophilic syndromes. Read more.
Cartoon image of an eosinophil, a type of white blood cell.
Researchers found that a rheumatoid arthritis drug vastly reduces symptoms of rare immune diseases like CANDLE and SAVI syndromes. Read more.
NIH clinicians treat Isaac Barchus, a young man living with CANDLE syndrome.
NIAID launched a partnership with Children’s National Health System to advance treatment strategies for pediatric patients with allergic, immunologic and infectious diseases, including rare conditions like primary immune deficiency diseases. Read more.
NIAID Director Anthony S. Fauci, M.D., (right) and Children’s president and CEO Kurt Newman, M.D., (left) at the inaugural Children’s National-NIAID symposium.
A NIAID-supported study found that exercise can exacerbate symptoms of mastocytosis, a rare immune disease in which an excess of mast cells causes inflammatory symptoms. Read more.
NIAID staff do a warm-up before taking a run or brisk walk.
Scientists helped a young man with a rare genetic form of Crohn’s disease find a medication that worked for his severe symptoms. Read more.
The features shown in this biopsy of a 19-year-old man’s colon—including severe inflammation, erosion of tissues and loss of important immune cells—usually indicate graft-versus-host disease. NIAID researchers discovered the cause of the patient’s symptoms was actually a rare genetic variant of Crohn’s disease.