Chief, Humoral Immunology Core
Vaccine Research Center
Education:
Ph.D., 1998, Cornell University, Ithaca, NY
Biography
Nicole Doria-Rose, PhD is Chief of the Humoral Immunology Core at the Vaccine Research Center, National Institutes of Health, USA. She obtained her PhD from Cornell University in 1998 followed by post-doctoral work at the Seattle Biomedical Research Institute. Her research focus is the identification and characterization of broadly neutralizing antibodies from HIV-infected patients, with an emphasis on patients followed from the time of infection. She developed a high-throughput method for culturing and screening single B cells for antibody discovery, and with this method her team isolated the most potently HIV-neutralizing antibody yet known. At the Vaccine Research Center, she leads a program that evaluates the immune responses to HIV-1 infection and to novel immunogens, and investigates the clinical use of broadly neutralizing antibodies for prevention of HIV-1. She also led a team to develop a neutralization assay for SARS-CoV-2, the virus that causes COVID-19, and provided data in support of the mRNA vaccines now in use worldwide.