University of California, San Francisco
Project Title: Defining HIV Evolution at the Innate Immune Interface
Award Year: 2024
Biography
Dr. Tenthorey is broadly interested in how the innate immune system is built to withstand the evolutionary pressures of many different kinds of viral infections, including HIV. Jeannette embarked on her training in host-pathogen biology as undergraduate at Reed College and cut her teeth in biochemistry as a research technician with Dave Morgan at UCSF. As a Ph.D. student working with Russell Vance at UC Berkeley, Jeannette combined her love of infectious disease and biochemistry to investigate the structural mechanism of an innate immune sensor of intracellular bacterial pathogens. She completed her training in evolutionary biology as a postdoc with Harmit Malik at the Fred Hutchinson Cancer Center, where she probed the evolutionary landscape of an anti-retroviral protein to understand how it evolves to combat retroviral infection. Jeannette returned to UCSF in April 2023 to start her own lab.