The STAT3base contains a listing of STAT3 mutations in human HIES identified in the Laboratory of Clinical Immunology and Microbiology as well as those published in the literature.
More information about this resource is available at Database of Mutations Causing Human Hyper IgE Syndrome
Main Areas of Focus
- To demonstrate critical regions of the protein and sites of recurrent mutations resulting in HIES.
Tools
- Schematic of mutations causing HIES
- Distribution of STAT3 mutations causing HIES
- Clinical features list