Clinical Islet Transplantation Consortium (CITC)

The Clinical Islet Transplantation Consortium is a network of clinical centers and a data coordinating center established in 2004 to conduct studies of islet transplantation in patients with type 1 diabetes.

Main Areas of Focus

  • To improve the isolation and viability of islets
  • To reduce complications of the islet transplant procedure (e.g., bleeding and clotting in the blood vessels of the liver)
  • To reduce the side effects of immunosuppression
  • To achieve good blood sugar control without hypoglycemia
  • To follow the fate of islets after transplantation and determining why donor islets sometimes fail
  • To evaluate new ways to safely prevent immune rejection of donor tissues
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