The Childhood Asthma in Urban Settings (CAUSE) network focuses on understanding how the environment, allergens, and genetics interact with the body’s immune system to cause asthma and aggravate its symptoms.
Main Areas of Focus
- To understand the underlying mechanisms of candidate therapies
- To develop and validate biomarkers to measure disease stage, progression, and therapeutic effect of candidate treatments
- To assess how possible genetic and epigenetic (changes in gene expression or observable trait that are not caused by changes in DNA sequence) factors influence disease development, progression, and severity
- To define the development and unique mechanisms associated with asthma onset and severity in children living in urban settings
- To identify environmental factors associated with asthma in urban settings
See CAUSE clinical trials that are currently recruiting participants
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