The Consortium of Food Allergy Research (CoFAR) was established in fiscal year (FY) 2005 to support clinical research on food allergy. It was renewed in FY 2010 to continue several promising clinical studies from the original consortium and expanded to include research on the genetic causes underlying food allergy and the mechanisms of food allergy-associated eosinophilic esophagitis.
Main Areas of Focus
- To identify the mechanisms underlying the development of new food allergy and the mechanisms of loss of food allergy (i.e., emergence of oral tolerance to food allergens)
- To develop immune intervention strategies for the treatment of food allergy
- To identify the role of food allergy in EoE, and compare the genetic markers of EoE with those of food allergy involving immunoglobulin E, the primary antibody associated with allergic reactions
- To identify the genes associated with food allergy